Effects of Angiotensin-Converting Enzyme Inhibition and Angiotensin II AT1 Receptor Antagonism on Cardiac Parameters in Left Ventricular Hypertrophy

Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure

1991 • 8,296 citations

Effect of Captopril on Mortality and Morbidity in Patients with Left Ventricular Dysfunction after Myocardial Infarction

1992 • 5,885 citations

Angiotensin II receptors and angiotensin II receptor antagonists.

1993 • 1,843 citations

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure

1993 • 1,775 citations

Bioregulation of kinins: kallikreins, kininogens, and kininases.

1992 • 1,732 citations

Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators.

1993 • 1,240 citations

The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.

1995 • 918 citations

Hoe 140 a new potent and long acting bradykinin‐antagonist: in vivo studies

1991 • 841 citations

Influence of chronic captopril therapy on the infarcted left ventricle of the rat.

1985 • 824 citations

Two putative active centers in human angiotensin I-converting enzyme revealed by molecular cloning.

1988 • 741 citations

Remodeling of the rat right and left ventricles in experimental hypertension.

1990 • 676 citations

Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors.

1995 • 642 citations

Hoe 140 a new potent and long acting bradykinin‐antagonist: in vitro studies

1991 • 598 citations

Cardiomyopathy of Overload

1990 • 566 citations

Collagen remodeling of the pressure-overloaded, hypertrophied nonhuman primate myocardium.

1988 • 557 citations

A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin

1970 • 533 citations

Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure.

1991 • 466 citations

Anti-Aldosterone Treatment and the Prevention of Myocardial Fibrosis in Primary and Secondary Hyperaldosteronism

1993 • 432 citations

Converting Enzyme Inhibition Specifically Prevents the Development and Induces Regression of Cardiac Hypertrophy in Rats

1989 • 344 citations

Limitation of experimental infarct size by an angiotensin-converting enzyme inhibitor.

1982 • 321 citations

Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells

1991 • 288 citations

The angiotensin AT2 receptor stimulates protein tyrosine phosphatase activity and mediates inhibition of particulate guanylate cyclase

1992 • 252 citations

A specific B₂‐bradykinin receptor antagonist HOE 140 abolishes the antihypertrophic effect of ramipril

1992 • 236 citations

Angiotensin II stimulates collagen synthesis in cultured vascular smooth muscle cells

1991 • 230 citations

Regulation of fibrillar collagen types I and III and basement membrane type IV collagen gene expression in pressure overloaded rat myocardium.

1990 • 226 citations

Reduction of infarct size by local angiotensin-converting enzyme inhibition is abolished by a bradykinin antagonist

1990 • 204 citations

Book Review: The Coronary Arteries

1965 • 198 citations

Angiotensin-converting enzyme inhibition improves cardiac function. Role of bradykinin.

1994 • 185 citations

Patterns of myocardial fibrosis*1

1989 • 182 citations

Angiotensin II Receptor Blockade After Myocardial Infarction in Rats

1992 • 178 citations

Cellular Distribution of Angiotensin-Converting Enzyme After Myocardial Infarction

1995 • 157 citations

Effects of Losartan on Angiotensin and Bradykinin Peptides and Angiotensin-Converting Enzyme

1995 • 145 citations

Angiotensin II receptor binding following myocardial infarction in the rat

1994 • 136 citations

Effect of early onset angiotensin converting enzyme inhibition on myocardial capillaries.

1992 • 116 citations

The angiotensin AT2 receptor: searching for signal-transduction pathways and physiological function

1995 • 111 citations

Blockade of Bradykinin B ₂ Receptors Prevents the Increase in Capillary Density Induced by Chronic Angiotensin-Converting Enzyme Inhibitor Treatment in Stroke-Prone Spontaneously Hypertensive Rats

1997 • 108 citations

Effects of the angiotensin converting enzyme inhibitor, ramipril, in isolated ischaemic rat heart are abolished by a bradykinin antagonist

1988 • 108 citations

Cardiac and Vascular Effects of Long-term Losartan Treatment in Stroke-Prone Spontaneously Hypertensive Rats

1996 • 92 citations

Angiotensin-Converting Enzyme Inhibition in Infarct-Induced Heart Failure in Rats: Bradykinin Versus Angiotensin II

1994 • 91 citations

Angiotensin II and left ventricular growth in newborn pig heart

1991 • 79 citations

Effects of angiotensin II and angiotensin II antagonist saralasin on cell growth and renin in 3T3 and SV3T3 cells

1979 • 73 citations

The effects of long-term pressure-overload and aging on the myocardium

1981 • 70 citations

Reduction of myocardial infarct size by ramiprilat is independent of angiotensin II synthesis inhibition

1993 • 69 citations

HOE 140, a new highly potent and long-acting bradykinin antagonist in conscious rats

1991 • 69 citations

Inhibition of angiotensin converting enzyme: mechanism and substrate dependence

1984 • 67 citations

Converting enzyme inhibitors in cardiovascular therapy: current status and future potential

1994 • 61 citations

Exercise-induced myocardial capillary growth in the spontaneously hypertensive rat

1985 • 60 citations

Left Ventricular Hypertrophy

1991 • 56 citations

Angiotensin II Receptor Blockade After Myocardial Infarction in Rats: Effects on Hemodynamics, Myocardial DNA Synthesis, and Interstitial Collagen Content

1992 • 52 citations

Angiotensin receptors

1996 • 51 citations

Hemodynamic and neurohumoral effects of the angiotensin II antagonist losartan in patients with heart failure.

1994 • 49 citations

Protein-Tyrosine-Phosphatase Inhibition by Angiotensin-II in Rat Pheochromocytoma Cells Through Type-2 Receptor, at(2)

1994 • 47 citations

Distribution and metabolism of angiotensin I and II in the blood vessel wall.

1992 • 45 citations

Capillary neoformation in the rat heart-stereological studies on papillary muscles in hypertrophy and physiologic growth

1990 • 45 citations

LONG‐TERM ANGIOTENSIN II ANTAGONISM IN SPONTANEOUSLY HYPERTENSIVE RATS: EFFECTS ON BLOOD PRESSURE AND CARDIOVASCULAR AMPLIFIERS

1992 • 41 citations

Energetic changes of myocardium as an adaptation to chronic hemodynamic overload and thyroid gland activity

1985 • 34 citations

Left Ventricular Hypertrophy

1991 • 27 citations

Effect of Low-Dose Treatment with Perindopril on Cardiac Function in Stroke-Prone Spontaneously Hypertensive Rats

1994 • 26 citations

Signals for the Remodeling of the Cardiac Interstitium in Systemic Hypertension

1991 • 21 citations

Angiotensin II receptor antagonists and the kidney

1994 • 19 citations

Remodelling of the heart in DOCA-salt hypertensive rats by propranolol and by an alpha-2 agonist, rilmenidine

1989 • 17 citations

Effect on the myocardial energy metabolism of angiotensin-converting enzyme inhibition in chronic heart failure

1990 • 15 citations