Mucin Gene Expression during Differentiation of Human Airway Epithelia In Vitro

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

1990 • 994 citations

Epithelial Mucin Genes

1995 • 982 citations

Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells.

1996 • 499 citations

Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7).

1993 • 461 citations

Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization.

1993 • 455 citations

Cloning and sequencing of a human pancreatic tumor mucin cDNA.

1990 • 435 citations

Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.

1994 • 428 citations

Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs

1991 • 405 citations

Human gastric mucin. Identification of a unique species by expression cloning.

1993 • 370 citations

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene

1990 • 367 citations

A serum-free method for culturing normal human bronchial epithelial cells at clonal density

1985 • 344 citations

Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease

1997 • 284 citations

Expression of secretory mucin genes by human conjunctival epithelia.

1996 • 253 citations

MUC5AC, but not MUC2, is a prominent mucin in respiratory secretions

1996 • 232 citations

Human Mucin Genes Assigned to 11p15.5: Identification and Organization of a Cluster of Genes

1996 • 225 citations

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

1994 • 222 citations

Respiratory mucins: identification of core proteins and glycoforms

1996 • 184 citations

Identification of Two Glycoforms of the MUC5B Mucin in Human Respiratory Mucus

1997 • 182 citations

Growth and differentiation of human nasal epithelial cells in culture. Serum-free, hormone-supplemented medium and proteoglycan synthesis.

1985 • 169 citations

Chromosomal localization of a human mucin gene (MUC8) and cloning of the cDNA corresponding to the carboxy terminus.

1997 • 151 citations

Intracellular Cl- activity and cellular Cl- pathways in cultured human airway epithelium

1989 • 150 citations

MUC5B and MUC7 Are Differentially Expressed in Mucous and Serous Cells of Submucosal Glands in Human Bronchial Airways

1998 • 148 citations

Developmental Expression of Mucin Genes in the Human Respiratory Tract

1997 • 147 citations

Rat tracheal epithelial cell differentiation in vitro

1993 • 136 citations

Degenerate 87-base-pair tandem repeats create hydrophilic/hydrophobic alternating domains in human mucin peptides mapped to 11p15

1993 • 133 citations

A novel human airway mucin cDNA encodes a protein with unique tandem-repeat organization

1994 • 130 citations

Evidence for Different Human Tracheobronchial Mucin Peptides Deduced from Nucleotide cDNA Sequences

1991 • 122 citations

Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Phenotypic Analysis of Cell Cultures of Human Tracheal Epithelium, Tracheobronchial Glands, and Lung Carcinomas

1993 • 117 citations

Culture of human nasal epithelial cells on collagen matrix supports. A comparison of bioelectric properties of normal and cystic fibrosis epithelia.

1985 • 109 citations

Human Mucin Genes MUC2, MUC3,MUC4, MUC5AC, MUC5B, andMUC6 Express Stable and Extremely Large mRNAs and Exhibit a Variable Length Polymorphism

1998 • 108 citations

Regulation of the secretory phenotype of human airway epithelium by retinoic acid, triiodothyronine, and extracellular matrix.

1997 • 102 citations

Developmental expression of mucin genes MUC1 and MUC2

1994 • 98 citations

Airway Mucus: Basic Mechanisms and Clinical Perspectives

1997 • 98 citations

Growth and differentiation factors in tracheobronchial epithelium

1991 • 90 citations

Dexamethasone suppresses mucus production and MUC-2 and MUC-5AC gene expression by NCI-H292 cells

1996 • 89 citations

Characterization of the human cyclophilin gene and of related processed pseudogenes

1990 • 84 citations

Identification and characterization of the MUC2 (human intestinal mucin) gene 5′-flanking region: promoter activity in cultured cells

1997 • 82 citations

Heterogeneity of the composition and thickness of tracheal mucus in rats

1997 • 70 citations

Membrane-Bound (MUC1) and Secretory (MUC2, MUC3, and MUC4) Mucin Gene Expression in Human Lung Cancer

1996 • 70 citations

Structure and Chromosomal Localization of the Human Salivary Mucin Gene, MUC7

1996 • 66 citations

Human mucin genes: genomic organization and expression of MUC4, MUC5AC and MUC5B

1995 • 59 citations

Quantitation of mucin RNA by PCR reveals induction of both MUC2 and MUC5AC mRNA levels by retinoids

1996 • 57 citations

Human Tracheobronchial Submucosal Gland Cells in Culture

1990 • 54 citations

Plasticity in the airway epithelium

1990 • 52 citations

Pattern of mucin gene expression in normal and neoplastic lung tissues

1997 • 47 citations

Regional localization of the intestinal mucin gene MUC3 to chromosome 7q22

1992 • 39 citations

Mucin 4 (MUC4) gene: regional assignment (3q29) and RFLP analysis.

1992 • 38 citations

Localization and up-regulation of Mucin (MUC2) gene expression in human nasal biopsies of patients with cystic fibrosis

1997 • 32 citations

Quantitation of mucin mRNA in respiratory and intestinal epithelial cells.

1994 • 32 citations

Molecular Cloning of Human MUC3 cDNA Reveals a Novel 59 Amino Acid Tandem Repeat Region

1997 • 30 citations

Mucins secreted by a transformed cell line derived from human tracheal gland cells

1997 • 19 citations

Anti‐peptide monoclonal antibodies to intestinal mucin 3

1995 • 17 citations

Rheological Properties and Hydration of Airway Mucus

1997 • 9 citations

Mucus Hypersecretion and Its Role in the Airway Obstruction of Asthma and Chronic Obstructive Pulmonary Disease

1997 • 6 citations

Human tracheal mucins– is MUC5 more prominent in the epithelial surface than in the submucosa?

1995 • 4 citations