Identification and characterization of the MUC2 (human intestinal mucin) gene 5′-flanking region: promoter activity in cultured cells

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine V. Unitarian theory of the origin of the four epithelial cell types

1974 • 1,697 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

A Novel, Erythroid Cell-Specific Murine Transcription Factor that Binds to the CACCC Element and is Related to the Krüppel Family of Nuclear Proteins†

1993 • 703 citations

Heterogeneity of mucin gene expression in normal and neoplastic tissues.

1993 • 671 citations

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine II. Mucous cells

1974 • 618 citations

Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes

1992 • 577 citations

Molecular Cloning of Human Intestinal Mucin cDNAs

1989 • 544 citations

Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression.

1992 • 533 citations

Fine Structure Genetic Analysis of a β-Globin Promoter

1986 • 479 citations

Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization.

1993 • 455 citations

COMMON THEMES IN ASSEMBLY AND FUNCTION OF EUKARYOTIC TRANSCRIPTION COMPLEXES

1995 • 434 citations

Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.

1994 • 428 citations

A Homeodomain Protein Related to caudal Regulates Intestine-Specific Gene Transcription

1994 • 399 citations

Human colonic adenocarcinoma cells

1976 • 375 citations

Human gastric mucin. Identification of a unique species by expression cloning.

1993 • 370 citations

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene

1990 • 367 citations

Localization of mucin (MUC2 and MUC3) messenger RNA and peptide expression in human normal intestine and colon cancer

1994 • 284 citations

The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region.

1992 • 270 citations

Isolation of a Gene Encoding a Functional Zinc Finger Protein Homologous to Erythroid Krüppel-Like Factor: Identification of a New Multigene Family

1995 • 260 citations

Human Mucin Genes Assigned to 11p15.5: Identification and Organization of a Cluster of Genes

1996 • 225 citations

Alu: Structure, Origin, Evolution, Significance, and Function of One-Tenth of Human DNA

1996 • 190 citations

MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism.

1991 • 187 citations

Synergistic activation of the HTLV1 LTR Ets-responsive region by transcription factors Ets1 and Sp1.

1993 • 180 citations

Effects of sodium butyrate on human colonic adenocarcinoma cells. Induction of placental-like alkaline phosphatase.

1987 • 153 citations

Studies of intestinal stem cells using normal, chimeric, and transgenic mice ¹

1992 • 153 citations

Mucin gene expression in colonic tissues and cell lines.

1992 • 144 citations

Cooperation of GATA-1 and Sp1 can result in synergistic transcriptional activation or interference.

1993 • 116 citations

Cloning of GT Box-Binding Proteins: A Novel Spl Multigene Family Regulating T-Cell Receptor Gene Expression

1992 • 114 citations

Human mucin glycoproteins: varied structures predict diverse properties and specific functions

1995 • 101 citations

Human bronchus and intestine express the same mucin gene.

1991 • 94 citations

A Regulatory Element in Intron 1 of the Cystic Fibrosis Transmembrane Conductance Regulator Gene

1996 • 94 citations

Intestinal epithelial cell differentiation: new insights from mice, flies and nematodes

1995 • 89 citations

Molecular cloning of the amino-terminal region of a rat MUC 2 mucin gene homologue. Evidence for expression in both intestine and airway.

1994 • 79 citations

A simplification of the nuclear run-off transcription assay.

1989 • 75 citations

Discrimination Among Potential Activators of the β-Globin CACCC Element by Correlation of Binding and Transcriptional Properties

1993 • 74 citations

Regulation of parathyroid hormone-related protein (PTHrP) gene expression. Sp1 binds through an inverted CACCC motif and regulates promoter activity in cooperation with Ets1.

1994 • 74 citations

Molecular cloning of rat intestinal mucin. Lack of conservation between mammalian species.

1991 • 66 citations

The core polypeptide of cystic fibrosis tracheal mucin contains a tandem repeat structure. Evidence for a common mucin in airway and gastrointestinal tissue.

1990 • 64 citations

Regulated expression of an intestinal mucin gene in HT29 colonic carcinoma cells

1993 • 63 citations

Characterization of an Enhancer Element in the Human Apolipoprotein C-III Gene That Regulates Human Apolipoprotein A-I Gene Expression in the Intestinal Epithelium

1995 • 62 citations

Two GC Boxes (Sp1 Sites) Are Involved in Regulation of the Activity of the Epithelium-specific MUC1 Promoter

1996 • 60 citations

Purification and characterization of sialyl-Le(a)-carrying mucins of human bile; evidence for the presence of MUC1 and MUC3 apoproteins.

1994 • 55 citations

Regulation of lineage-specific transcription of the sucrase-isomaltase gene in transgenic mice and cell lines

1995 • 37 citations

Molecular Cloning of the Rat Intestinal Trefoil Factor Gene

1995 • 36 citations

Members of the Caudal Family of Homeodomain Proteins Repress Transcription from the Human Apolipoprotein B Promoter in Intestinal Cells

1996 • 36 citations

Altered glycosylation of mucin glycoproteins in colonic neoplasia

1992 • 24 citations

The establishment and characterization of two new cell lines derived from a single human colonic adenocarcinoma

1987 • 17 citations

Characterization of the nuclear proteins binding the CACCC element of a glucocorticoid‐responsive enhancer in the tyrosine aminotransferase gene

1993 • 12 citations

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