Patterns of viral replication correlate with outcome in simian immunodeficiency virus (SIV)-infected macaques: effect of prior immunization with a trivalent SIV vaccine in modified vaccinia virus Ankara

Statistical principles in experimental design.

1962 • 27,228 citations

The Statistical Analysis of Failure Time Data.

1981 • 10,224 citations

Multivariate Statistical Methods

2008 • 5,797 citations

Statistical Principles in Experimental Design

1992 • 4,547 citations

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

Viral dynamics in human immunodeficiency virus type 1 infection

1995 • 3,277 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

The Statistical Analysis of Failure Time Data

1982 • 2,300 citations

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1993 • 1,822 citations

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

1993 • 1,450 citations

High Levels of HIV-1 in Plasma During All Stages of Infection Determined By Competitive PCR

1993 • 1,263 citations

Virologic and Immunologic Characterization of Long-Term Survivors of Human Immunodeficiency Virus Type 1 Infection

1995 • 1,044 citations

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

1992 • 1,025 citations

Absence of Intact nef Sequences in a Long-Term Survivor with Nonprogressive HIV-1 Infection

1995 • 1,008 citations

Studies in Subjects with Long-Term Nonprogressive Human Immunodeficiency Virus Infection

1995 • 750 citations

General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes

1984 • 652 citations

Nonreplicating vaccinia vector efficiently expresses recombinant genes.

1992 • 598 citations

Cellular Proteins Bound to Immunodeficiency Viruses: Implications for Pathogenesis and Vaccines

1992 • 570 citations

NYVAC: A highly attenuated strain of vaccinia virus

1992 • 473 citations

Mapping of deletions in the genome of the highly attenuated vaccinia virus MVA and their influence on virulence

1991 • 470 citations

Decreased virulence of recombinant vaccinia virus expression vectors is associated with a thymidine kinase-negative phenotype

1985 • 447 citations

Protection of Macaques Against SIV Infection by Subunit Vaccines of SIV Envelope Glycoprotein gp160

1992 • 340 citations

Quantitative competitive polymerase chain reaction for accurate quantitation of HIV DNA and RNA species.

1993 • 319 citations

Lymphoid Germinal Centers Are Reservoirs of Human Immunodeficiency Virus Type 1 RNA

1991 • 301 citations

A recombinant vector derived from the host range-restricted and highly attenuated MVA strain of vaccinia virus stimulates protective immunity in mice to influenza virus

1994 • 291 citations

Immunopathogenic events in acute infection of rhesus monkeys with simian immunodeficiency virus of macaques

1994 • 251 citations

Necropsy Findings in Rhesus Monkeys Experimentally Infected with Cultured Simian Immunodeficiency Virus (SIV)/Delta

1988 • 232 citations

Passage history, properties and applicability of the attenuated vaccinia virus strain MVA

1975 • 230 citations

In vitro mutagenesis of the promoter region for a vaccinia virus gene: evidence for tandem early and late regulatory signals

1985 • 219 citations

Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication

1995 • 211 citations

Evaluation of antiviral drugs and neutralizing antibodies to human immunodeficiency virus by a rapid and sensitive microtiter infection assay

1988 • 205 citations

Inhibition of human immunodeficiency virus replication in acutely infected CD4+ cells by CD8+ cells involves a noncytotoxic mechanism

1991 • 173 citations

A Distribution-Free Test for Tumor-Growth Curve Analyses with Application to an Animal Tumor Immunotherapy Experiment

1981 • 172 citations

Viral DNA and mRNA expression correlate with the stage of human immunodeficiency virus (HIV) type 1 infection in humans: evidence for viral replication in all stages of HIV disease

1992 • 166 citations

Spectrum of disease in macaque monkeys chronically infected with SIV/SMM

1989 • 158 citations

HTLV-III expression in infected lymph nodes and relevance to pathogenesis of lymphadenopathy.

1986 • 155 citations

Pathogenic diversity of simian immunodeficiency viruses

1994 • 153 citations

A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge

1994 • 142 citations

Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV

1990 • 136 citations

Virus strategies for evasion of the host response to infection

1994 • 116 citations

Variable course of primary simian immunodeficiency virus infection in lymph nodes: relation to disease progression

1994 • 83 citations

Studies on the Specificity of the Vaccine Effect Elicited by Inactivated Simian Immunodeficiency Virus

1993 • 77 citations

Immune response of rhesus macaques to recombinant simian immunodeficiency virus gp130 does not protect from challenge infection

1993 • 77 citations

Long–term protection against SIV–induced disease in macaques vaccinated with a live attenuated HIV–2 vaccine

1995 • 66 citations

Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines

1994 • 64 citations

Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge.

1992 • 63 citations

Prolonged Clinical Latency and Survival of Macaques Given a Whole Inactivated Simian Immunodeficiency Virus Vaccine

1994 • 44 citations

Distribution of SIV in Lymph Nodes of Serially Sacrificed Rhesus Monkeys

1995 • 37 citations

Immunization with whole inactivated vaccine protects from infection by SIV grown in human but not macaque cells

1994 • 35 citations

Ultrastructural analysis of germinal centers in lymph nodes of patients with HIV-1-induced persistent generalized lymphadenopathy: evidence for persistence of infection.

1989 • 23 citations

An interactive computer program for the analysis of growth curves

1987 • 9 citations

Deleted Work

1955 • 0 citations