Inhibition of human immunodeficiency virus replication in acutely infected CD4+ cells by CD8+ cells involves a noncytotoxic mechanism

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

1968 • 1,363 citations

"Panning" for lymphocytes: a method for cell selection.

1978 • 1,319 citations

Quantitation of Human Immunodeficiency Virus Type 1 in the Blood of Infected Persons

1989 • 1,090 citations

CD8 ⁺ Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication

1986 • 1,010 citations

HIV-specific cytotoxic T lymphocytes in seropositive individuals

1987 • 797 citations

Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.

1985 • 545 citations

AIDS virus-specific cytotoxic T lymphocytes in lung disorders

1987 • 539 citations

Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

1988 • 509 citations

Characterization of the AIDS-associated retrovirus reverse transcriptase and optimal conditions for its detection in virions

1985 • 449 citations

Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes.

1987 • 372 citations

Interferon-α But Not AZT Suppresses HIV Expression in Chronically Infected Cell Lines

1989 • 339 citations

Lymphokine and nonlymphokine mRNA levels in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A.

1986 • 293 citations

A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytes.

1989 • 258 citations

A diffusible lymphokine produced by CD8+ T lymphocytes suppresses HIV replication.

1989 • 221 citations

CD8+ T cells inhibit HIV replication in naturally infected CD4+ T cells. Evidence for a soluble inhibitor.

1990 • 196 citations

Amplification of HTLV-III/LAV infection by antigen-induced activation of T cells and direct suppression by virus of lymphocyte blastogenic responses.

1987 • 194 citations

Suppression of simian immunodeficiency virus replication in vitro by CD8+ lymphocytes.

1988 • 157 citations

A novel addition to the T cell repertory. Cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells.

1990 • 133 citations

In vitro anti-human immunodeficiency virus activities of tumor necrosis factor-alpha and interferon-gamma.

1988 • 132 citations

HIV-infected humans, but not chimpanzees, have circulating cytotoxic T lymphocytes that lyse uninfected CD4+ cells.

1990 • 131 citations

Phenotypic heterogeneity of cerebrospinal fluid-derived HIV-specific and HLA-restricted cytotoxic T-cell clones

1988 • 129 citations

Group-specific, major histocompatibility complex class I-restricted cytotoxic responses to human immunodeficiency virus 1 (HIV-1) envelope proteins by cloned peripheral blood T cells from an HIV-1-infected individual.

1988 • 129 citations

Antibody 3G8, specific for the human neutrophil Fc receptor, reacts with natural killer cells.

1984 • 119 citations

Optimal conditions for recovery of the human immunodeficiency virus from peripheral blood mononuclear cells

1988 • 113 citations

CD8+ T lymphocyte control of HIV replication in cultured CD4+ cells varies among infected individuals

1989 • 93 citations

Regulation of cytolytic activity in CD3- and CD3+ killer cell clones by monoclonal antibodies (anti-CD16, anti-CD2, anti-CD3) depends on subclass specificity of target cell IgG-FcR.

1987 • 85 citations

CD8+ lymphocytes suppress HIV production by autologous CD4+ cells without eliminating the infected cells from culture

1990 • 83 citations

Interference with human immunodeficiency virus (HIV) replication by CD8+ T cells in peripheral blood leukocytes of asymptomatic HIV carriers in vitro

1990 • 76 citations

Negative regulation of human immune deficiency virus replication in monocytes. Distinctions between restricted and latent expression in THP- 1 cells

1990 • 67 citations

MT-4 plaque formation can distinguish cytopathic subtypes of the human immunodeficiency virus (HIV)

1988 • 63 citations

The human LT system. XI. Identification of LT and "TNF-like" forms from stimulated natural killers, specific and nonspecific cytotoxic human T cells in vitro.

1986 • 53 citations

Long-term cultivation of T-cell subsets from patients with acquired immune deficiency syndrome

1985 • 47 citations

Inactivation of HIV-1 by trypsin and its use in demonstrating specific virus infection of cells

1991 • 41 citations