A partially attenuated simian immunodeficiency virus induces host immunity that correlates with resistance to pathogenic virus challenge

A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12

1938 • 19,183 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

A simple method of estimating 50 per cent end points

1938 • 8,381 citations

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

1993 • 1,822 citations

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1991 • 1,613 citations

Protective Effects of a Live Attenuated SIV Vaccine with a Deletion in the nef Gene

1992 • 1,025 citations

Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids

1985 • 580 citations

Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus

1992 • 496 citations

Pathogenesis of Infectious Disease

1978 • 371 citations

Increasing Viral Burden in CD4+ T Cells from Patients with Human Immunodeficiency Virus (HIV) Infection Reflects Rapidly Progressive Immunosuppression and Clinical Disease

1990 • 281 citations

Prolonged antigen half-life in the lymphoid follicles of specifically immunized mice.

1979 • 186 citations

Localization of simian immunodeficiency virus in the central nervous system of rhesus monkeys.

1991 • 177 citations

Human immunodeficiency virus-specific cytotoxic responses of seropositive individuals: distinct types of effector cells mediate killing of targets expressing gag and env proteins

1989 • 152 citations

Immunization with a live, attenuated simian immunodeficiency virus (SIV) prevents early disease but not infection in rhesus macaques challenged with pathogenic SIV

1990 • 136 citations

Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeys

1993 • 119 citations

Virus-Induced Immunosuppression: Infections with Measles Virus and Human Immunodeficiency Virus

1989 • 113 citations

Cellular localization of simian immunodeficiency virus in lymphoid tissues. I. Immunohistochemistry and electron microscopy.

1989 • 110 citations

Simian immunodeficiency virus (SIV) infection of infant rhesus macaques as a model to test antiretroviral drug prophylaxis and therapy: oral 3'-azido-3'-deoxythymidine prevents SIV infection

1992 • 98 citations

Viral determinants of simian immunodeficiency virus (SIV) virulence in rhesus macaques assessed by using attenuated and pathogenic molecular clones of SIVmac

1993 • 91 citations

Genetic and Biological Comparisons of Pathogenic and Nonpathogenic Molecular Clones of Simian Immunodeficiency Virus (SIV_MAC)

1992 • 91 citations

The Lentiviruses: Maedi/Visna, Caprine Arthritis-Encephalitis, and Equine Infectious Anemia

1988 • 89 citations

The gag-specific cytotoxic T lymphocytes in rhesus monkeys infected with the simian immunodeficiency virus of macaques.

1990 • 87 citations

Titration and Characterization of Two Rhesus-Derived SIV_macChallenge Stocks

1994 • 84 citations

Rhesus Macaques Inoculated With Molecularly Cloned Simian Immunodeficiency Virus

1989 • 83 citations

Interference patterns of human immunodeficiency viruses HIV-1 and HIV-2

1990 • 73 citations

Reduced Virus Load in Rhesus Macaques Immunized with Recombinant gp160 and Challenged with Simian Immunodeficiency Virus

1994 • 64 citations

IL-4 (B cell-stimulatory factor 1) regulates multiple aspects of influenza virus-specific cell-mediated immunity.

1988 • 58 citations

Identification of viral determinants of macrophage tropism for simian immunodeficiency virus SIVmac

1991 • 56 citations

Efficacy of live‐attenuated and whole‐inactivated simian immunodeficiency virus vaccines against vaginal challenge with virulent SIV

1992 • 55 citations

Development of simian immunodeficiency virus isolation, titration, and neutralization assays which use whole blood from rhesus monkeys and an antigen capture enzyme-linked immunosorbent assay

1991 • 52 citations

The Simian Retroviruses SIV and SRV

1994 • 47 citations

Animal Models for Acquired Immunodeficiency Syndrome

1992 • 43 citations

HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II-restricted T lymphocytes.

1993 • 21 citations

Animal Virus Infections That Defy Vaccination: Equine Infectious Anemia, Caprine Arthritis-Encephalitis, Maedi-Visna, and Feline Infectious Peritonitis

1989 • 20 citations

High Concentration of Peripheral Blood Mononuclear Cells Harboring Infectious Virus Correlates with Rapid Progression of Human Immunodeficiency Virus Type 1-Related Diseases

1993 • 14 citations

Human Immunodeficiency Virus: An Agent That Defies Vaccination

1989 • 6 citations