Age-dependent silencing of globin transgenes in the mouse

Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ.

1988 • 487 citations

Inactivation of gene expression in plants as a consequence of specific sequence duplication.

1994 • 462 citations

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

1987 • 440 citations

The basics of basal transcription by RNA polymerase II

1994 • 409 citations

Transformation of white locus DNA in Drosophila: Dosage compensation, zeste interaction, and position effects

1984 • 388 citations

A major positive regulatory region located far upstream of the human alpha-globin gene locus.

1990 • 337 citations

Enhancers increase the probability but not the level of gene expression.

1995 • 293 citations

Epigenetic changes in the expression of the maize A1 gene inPetunia hybrida: Role of numbers of integrated gene copies and state of methylation

1990 • 289 citations

An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes.

1989 • 280 citations

Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice.

1992 • 218 citations

Improved FACS‐Gal: Flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs

1991 • 192 citations

Transcriptional enhancers act in cis to suppress position-effect variegation.

1996 • 187 citations

Position effect variegation in the mouse

1974 • 184 citations

Conversion of Normal Behavior to Shiverer by Myelin Basic Protein Antisense cDNA in Transgenic Mice

1988 • 182 citations

Characterization of the Major Regulatory Element Upstream of the Human a-Globin Gene Cluster

1991 • 175 citations

Position-dependent variegation of globin transgene expression in mice.

1995 • 159 citations

Developmental regulation of human gamma-globin genes in transgenic mice.

1993 • 100 citations

Copy Number and Orientation Determine the Susceptibility of a Gene to Silencing by Nearby Heterochromatin in Drosophila

1996 • 94 citations

Position effect and related phenomena

1992 • 91 citations

Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice.

1992 • 73 citations

Modulation of transfected gene expression mediated by changes in chromatin structure

1982 • 72 citations

Analysis of the human alpha-globin gene cluster in transgenic mice.

1993 • 65 citations

A single beta-globin locus control region element (5' hypersensitive site 2) is sufficient for developmental regulation of human globin genes in transgenic mice.

1992 • 57 citations

Random activation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element.

1995 • 52 citations

Mosaic expression of a tyrosinase fusion gene in albino mice yields a heritable striped coat color pattern in transgenic homozygotes.

1991 • 52 citations

Analysis of a 70 kb segment of DNA containing the human ζ and α-globin genes linked to their regulatory element (HS-40) in transgenic mice

1994 • 45 citations

Clonal coat color variation due to a transforming gene expressed in melanocytes of transgenic mice.

1991 • 42 citations

Limited transcription of rat elastase I transgene repeats in transgenic mice.

1988 • 35 citations

The developmental regulation of the human ζ-globin gene in transgenic mice employing β-galactosidase as a reporter gene

1992 • 33 citations

Developmental Regulation of Human γ-Globin Genes in Transgenic Mice

1993 • 28 citations

Mosaic expression of an Hprt transgene integrated in a region of Y heterochromatin

1994 • 25 citations

Position effect variegation in yeast

1994 • 25 citations

Analysis of the Developmental and Transcriptional Potentiation Functions of 5′HS2 of the Murine β-Globin Locus Control Region in Transgenic Mice

1994 • 14 citations

Cited By (0)

Loading...