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A Molecular and Cellular Theory of Depression

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BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra

1991 • 1,487 citations

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1995 • 1,354 citations

Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

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Distribution of Brain-Derived Neurotrophic Factor (BDNF) Protein and mRNA in the Normal Adult Rat CNS: Evidence for Anterograde Axonal Transport

1997 • 1,093 citations

A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity

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Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

1990 • 899 citations

Anterograde transport of brain-derived neurotrophic factor and its role in the brain

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The changing scene of neurotrophic factors

1991 • 827 citations

Emotional memory systems in the brain

1993 • 805 citations

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1991 • 610 citations

Opposing Roles for Endogenous BDNF and NT-3 in Regulating Cortical Dendritic Growth

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Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs

1992 • 564 citations

Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity

1978 • 550 citations

Widespread Expression of BDNF But Not NT3 by Target Areas of Basal Forebrain Cholinergic Neurons

1990 • 529 citations

Pharmacological characterization of dopamine systems in the nucleus accumbens core and shell

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The contribution of the amygdala to normal and abnormal emotional states

1993 • 418 citations

Enhancement of Locomotor Activity and Conditioned Reward to Cocaine by Brain-Derived Neurotrophic Factor

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Limbic motor circuits and neuropsychiatry

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Neurotrophin trafficking by anterograde transport

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Induction of depolarization block in midbrain dopamine neurons by repeated administration of haloperidol: analysis using in vivo intracellular recording.

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Prefrontal cortical dopamine depletion enhances the responsiveness of mesolimbic dopamine neurons to stress

1990 • 308 citations

Activity‐dependent and hormonal regulation of neurotrophin mRNA levels in brain–implications for neuronal plasticity

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Endogenous brain-derived neurotrophic factor is anterogradely transported in primary sensory neurons

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Spontaneous orofacial movements induced in rodents by very long-term neuroleptic drug administration: phenomenology, pathophysiology and putative relationship to tardive dyskinesia

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Dopaminergic Modulation of Glutamate Release in Striatum as Measured by Microdialysis

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Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations

1994 • 203 citations

Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine

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TrkB Signaling Modulates Spine Density and Morphology Independent of Dendrite Structure in Cultured Neonatal Purkinje Cells

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Bilateral regulation of glutamate tissue and extracellular levels in caudate-putamen by midbrain dopamine neurons

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Dopaminergic stimulation up‐regulates the in vivo expression of brain‐derived neurotrophic factor (BDNF) in the striatum

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The effects of haloperidol on synaptic patterns in the rat striatum

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Brain-derived neurotrophic factor and neurotrophin-3 mRNAs are expressed in ventral midbrain regions containing dopaminergic neurons

1992 • 123 citations

Regional, reversible ultrastructural changes in rat brain with chronic neuroleptic treatment

1989 • 118 citations

Actions of clozapine and haloperidol on the extracellular levels of excitatory amino acids in the prefrontal cortex and striatum of conscious rats

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Chapter 28 Theories of basal forebrain organization and the “emotional motor system”

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Intrastriatal Infusions of Brain-Derived Neurotrophic Factor: Retrograde Transport and Colocalization with Dopamine Containing Substantia Nigra Neurons in Rat

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Ultrastructural correlates of haloperidol‐induced oral dyskinesias in rat striatum

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Alterations in mRNA levels of D2 receptors and neuropeptides in striatonigral and striatopallidal neurons of rats with neuroleptic‐induced dyskinesias

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Pharmacological and neurochemical differences between acute and tardive vacuous chewing movements induced by haloperidol

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Haloperidol-Induced Plasticity of Axon Terminals in Rat Substantia Nigra

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A Clinical Guide to Antipsychotic Drugs

1992 • 68 citations

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Effect of haloperidol and clozapine on the density of “perforated” synapses in caudate, nucleus accumbens, and medial prefrontal cortex

1992 • 63 citations

An improved procedure for the immunohistochemical localization of nerve growth factor-like immunoreactivity

1994 • 62 citations

The effects of chronic haloperidol administration on GABA‐immunoreactive. Axon terminals in rat medial prefrontal cortex

1994 • 61 citations

Acute versus chronic haloperidol: relationship between tolerance to catalepsy and striatal and accumbens dopamine, GABA and acetylcholine release

1994 • 53 citations

DIFFERENTIAL EXPRESSION OF c-fos mRNA IN RAT PREFRONTAL CORTEX, STRIATUM, N. ACCUMBENS AND LATERAL SEPTUM AFTER TYPICAL AND ATYPICAL ANTIPSYCHOTICS: AN IN SITU HYBRIDIZATION STUDY

1996 • 49 citations

Striatal Extracellular Dopamine Levels in Rats with Haloperidol-Induced Depolarization Block of Substantia Nigra Dopamine Neurons

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Correlation of vacuous chewing movements with morphological changes in rats following 1-year treatment with haloperidol

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Neurotrophic factors in memory disorders

1994 • 26 citations

Optimal Effectiveness of BDNF for Fetal Nigral Transplants Coincides with the Ontogenic Appearance of BDNF in the Striatum

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Optimal effectiveness of BDNF for fetal nigral transplants coincides with the ontogenic appearance of BDNF in the striatum.

1998 • 24 citations

Neuroleptics cause stimulation of dopamine D1 receptors and their desensitization after chronic treatment

1994 • 19 citations

Effects of chronic neuroleptic treatment on dopamine release: Insights from studies using 3-methoxytyramine

1996 • 17 citations

Coadministration of haloperidol and SCH-23390 prevents the increase in "perforated" synapses due to either drug alone.

1992 • 17 citations

Changes in striatal dopamine release and metabolism during and after subchronic haloperidol administration in rats

1992 • 16 citations

Morphological Changes in Met⁵‐enkephalin‐immunoreactive Synaptic Boutons in the Rat Neostriatum after Haloperidol Decanoate Treatment

1996 • 9 citations

The Effects of Acute and Chronic Haloperidol Treatment on Dopamine Release Mediated by the Medial Forebrain Bundle in the Striatum and Nucleus Accumbens

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Dopamine release and uptake kinetics in the putamen of non-human primate striatum in vitro: Species and region differences

2000 • 4 citations