Molecular cloning of a ligand for the flt3flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific Activity

1962 • 6,970 citations

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1987 • 5,745 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Analysis of membrane and surface protein sequences with the hydrophobic moment plot

1984 • 2,234 citations

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

1990 • 1,763 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1986 • 1,244 citations

Identification of Heregulin, a Specific Activator of p185 ^erbB2

1992 • 963 citations

A Short Polypeptide Marker Sequence Useful for Recombinant Protein Identification and Purification

1988 • 934 citations

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1990 • 870 citations

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant

1991 • 740 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.

1991 • 677 citations

Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.

1992 • 650 citations

The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

1989 • 645 citations

Isolation of a Novel Receptor cDNA Establishes the Existence of Two PDGF Receptor Genes

1989 • 610 citations

A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations

1991 • 606 citations

Neu differentiation factor: A transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit

1992 • 579 citations

CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factor

1983 • 536 citations

In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells

1992 • 520 citations

Triplet repeat mutations in human disease

1992 • 417 citations

cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

1989 • 413 citations

A restricted cytoplasmic region of IL-2 receptor β chain is essential for growth signal transduction but not for ligand binding and internalization

1989 • 370 citations

Cellular and developmental properties of fetal hematopoietic stem cells

1990 • 317 citations

Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family.

1991 • 300 citations

Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains.

1991 • 300 citations

Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor

1993 • 280 citations

Induction of active and adoptive relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein

1992 • 231 citations

Expression of the FMS/KIT-like gene FLT3 in human acute leukemias of the myeloid and lymphoid lineages

1992 • 231 citations

The fibroblast growth factor family.

1990 • 219 citations

Kluyveromyces as a Host for Heterologous Gene Expression: Expression and Secretion of Prochymosin

1990 • 195 citations

Genes with triplet repeats: candidate mediators of neuropsychiatric disorders

1993 • 187 citations

Three-Dimensional Structure of Dimeric Human Recombinant Macrophage Colony-Stimulating Factor

1992 • 174 citations

Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors.

1985 • 173 citations

The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells.

1991 • 157 citations

Developmental abnormalities in Steel17H mice result from a splicing defect in the steel factor cytoplasmic tail.

1992 • 134 citations

Human CD34+ HLA-DR- bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis.

1991 • 132 citations

Human macrophage-colony stimulating factor: Alternative RNA and protein processing from a single gene

1988 • 128 citations

The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGFα into soluble growth factor

1992 • 126 citations

The interaction of monoclonal antibodies with MHC class I antigens on mouse spleen cells. I. Analysis of the mechanism of binding.

1984 • 115 citations

Characterization of the protein encoded by the flt3 (flk2) receptor-like tyrosine kinase gene.

1993 • 111 citations

Cell surface antigens expressed by subsets of pre-B cells and B cells.

1984 • 111 citations

High-level secretion of correctly processed recombinant human interleukin-1β in Kluyveromyces lactis

1991 • 106 citations

Isolation of murine fetal hemopoietic progenitor cells and selective fractionation of various erythroid precursors

1981 • 98 citations

Biochemical characterization and analysis of the transforming potential of the FLT3/FLK2 receptor tyrosine kinase.

1993 • 95 citations

RAPID ISOLATION OF HUMAN CD34 HEMATOPOIETIC STEM CELLS—PURGING OF HUMAN TUMOR CELLS

1992 • 90 citations

Amino acid sequence and post-translational modification of stem cell factor isolated from buffalo rat liver cell-conditioned medium

1991 • 80 citations

Enrichment for CFU-C from murine and human bone marrow using soybean agglutinin

1982 • 46 citations

Thymus reconstitution by c-kit-expressing hematopoietic stem cells purified from adult mouse bone marrow.

1992 • 38 citations

Characterization of the gene-product of the Steel locus

1991 • 26 citations

Depletion of stromal cell elements in human marrow grafts separated by soybean agglutinin

1985 • 26 citations

Scatter factor and its relationship to hepatocyte growth factor and met.

1991 • 21 citations

MALIGNED: a multiple sequence alignment editor

1992 • 20 citations

Biological Activities and Potential Therapeutic Uses of Steel Factor; A New Growth Factor Active on Multiple Hematopoietic Lineages

1992 • 18 citations

Chapter 15 Analysis and Sorting of Hematopoietic Stem Cells from Mouse Bone Marrow

1994 • 8 citations