Lymphoma models for B cell activation and tolerance. X. Anti-mu-mediated growth arrest and apoptosis of murine B cell lymphomas is prevented by the stabilization of myc.

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

Thymocyte apoptosis induced by p53-dependent and independent pathways

1993 • 2,322 citations

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1985 • 1,782 citations

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

1989 • 1,031 citations

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1989 • 990 citations

Apoptotic cell death induced by c-myc is inhibited by bcl-2

1992 • 981 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Role for c-myc in Activation-Induced Apoptotic Cell Death in T Cell Hybridomas

1992 • 705 citations

A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1

1987 • 696 citations

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

1991 • 576 citations

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1991 • 541 citations

Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product

1991 • 326 citations

Anti‐immunoglobulin antibodies induce apoptosis in immature B cell lymphomas

1990 • 253 citations

Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation.

1984 • 234 citations

Inhibition of c-myc expression by phosphorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer.

1991 • 177 citations

Inhibitory effects of antisense oligodeoxynucleotides targeting c-myc mRNA on smooth muscle cell proliferation and migration.

1993 • 165 citations

Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product.

1991 • 120 citations

Lymphoma models for B cell activation and tolerance. III. Cell cycle dependence for negative signalling of WEHI-231 B lymphoma cells by anti-mu.

1986 • 112 citations

Specific regulation of c-myc oncogene expression in a murine B-cell lymphoma.

1984 • 100 citations

Abrogation by c-myc of Gl phase arrest induced by RB protein but not by p53

1992 • 99 citations

A simple and fast method to extract RNA from tissue culture cells.

1990 • 88 citations

Transforming growth factor beta 1 regulation of c-myc expression, pRB phosphorylation, and cell cycle progression in keratinocytes.

1992 • 81 citations

Enhanced translation and increased turnover of c-myc proteins occur during differentiation of murine erythroleukemia cells.

1990 • 79 citations

Lymphoma models for B-cell activation and tolerance

1985 • 69 citations

Up-regulation of c-fos expression is a component of the mIg signal transduction mechanism but is not indicative of competence for proliferation.

1988 • 62 citations

Anti-immunoglobulin treatment of murine B-cell lymphomas induces active transforming growth factor beta but pRB hypophosphorylation is transforming growth factor beta independent.

1992 • 55 citations

Transcription of three c-myc exons is enhanced in chicken bursal lymphoma cell lines.

1985 • 49 citations

Antigen receptor-induced cell cycle arrest in WEHI-231 B lymphoma cells depends on the duration of signaling before the G1 phase restriction point.

1990 • 48 citations

Changes in phosphorylation of myc oncogene and RB antioncogene protein products during growth arrest of the murine lymphoma WEHI 231 cell line.

1991 • 34 citations

Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product

1991 • 19 citations

Lymphoma models for B cell activation and tolerance. V. Anti-Ig mediated growth inhibition is reversed by phorbol myristate acetate but does not involve changes in cytosolic free calcium.

1987 • 19 citations

Enhanced Translation and Increased Turnover of c-myc Proteins Occur during Differentiation of Murine Erythroleukemia Cells

1990 • 18 citations

Efficient subcloning of DNA fragments amplified by crude oligonucleotides.

1990 • 11 citations

Antigen Receptor-Induced Cell Cycle Arrest in WEHI-231 B Lymphoma Cells Depends on the Duration of Signaling before the G₁ Phase Restriction Point

1990 • 10 citations

Synergy between TGF‐β and Anti‐IgM in Growth Inhibition of CD5⁺ B‐Cell Lymphomas^a

1992 • 7 citations