Branching Morphogenesis of theDrosophilaTracheal System

A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF

2001 • 2,481 citations

HIF-1, O2, and the 3 PHDs

2001 • 917 citations

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

1998 • 865 citations

sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways

1998 • 745 citations

Ternary complex factors: growth factor regulated transcriptional activators

1994 • 686 citations

Tube Morphogenesis

2003 • 657 citations

branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching

1996 • 631 citations

Building epithelial architecture: insights from three-dimensional culture models

2002 • 584 citations

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

2002 • 539 citations

Genetic Control of Branching Morphogenesis

1999 • 499 citations

Sprouty, an Intracellular Inhibitor of Ras Signaling

1999 • 462 citations

breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells.

1992 • 419 citations

In Situ Activation Pattern of Drosophila EGF Receptor Pathway During Development

1997 • 372 citations

Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development

1999 • 367 citations

Development of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events

1996 • 365 citations

Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless

2001 • 325 citations

An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo

1995 • 312 citations

trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila.

1996 • 264 citations

Tubulogenesis in Drosophila: a requirement for the trachealess gene product.

1996 • 264 citations

Sprouty is a general inhibitor of receptor tyrosine kinase signaling

1999 • 261 citations

Role of heparan sulfate in fibroblast growth factor signalling: a structural view

2001 • 261 citations

Nitric Oxide Contributes to Behavioral, Cellular, and Developmental Responses to Low Oxygen in Drosophila

1999 • 257 citations

Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila

1999 • 254 citations

Oxygen Regulation of Airway Branching in Drosophila Is Mediated by Branchless FGF

1999 • 247 citations

Control of the Hypoxic Response in Drosophila melanogaster by the Basic Helix-Loop-Helix PAS Protein Similar

2002 • 236 citations

FGF Is an Essential Mitogen and Chemoattractant for the Air Sacs of the Drosophila Tracheal System

2002 • 228 citations

The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension.

1991 • 217 citations

Genetic control of epithelial tube size in the Drosophila tracheal system

2000 • 201 citations

Developmental function of Elf-1: an essential transcription factor during embryogenesis in Drosophila.

1991 • 191 citations

The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development

1997 • 185 citations

The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system

1996 • 185 citations

The ubiquitin ligase Hyperplastic discs negatively regulateshedgehoganddecapentaplegicexpression by independent mechanisms

2002 • 174 citations

Genetic control of epithelial tube fusion during Drosophila tracheal development

1996 • 174 citations

Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor Escargot

1996 • 170 citations

The Drosophila Protein Dof Is Specifically Required for FGF Signaling

1998 • 166 citations

mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family

2002 • 165 citations

drifter, a Drosophila POU-domain transcription factor, is required for correct differentiation and migration of tracheal cells and midline glia.

1995 • 164 citations

Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration.

1994 • 156 citations

In Vivo Imaging Reveals Different Cellular Functions for FGF and Dpp Signaling in Tracheal Branching Morphogenesis

2002 • 156 citations

Regulated Breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system.

1996 • 146 citations

The PAS domain confers target gene specificity of DrosophilabHLH/PAS proteins

1997 • 138 citations

Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis.

1994 • 137 citations

Transcriptional regulation of breathless FGF receptor gene by binding of TRACHEALESS/dARNT heterodimers to three central midline elements in Drosophila developing trachea

1997 • 134 citations

Heartbroken is a specific downstream mediator of FGF receptor signalling in Drosophila

1998 • 131 citations

The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered

1996 • 130 citations

Evidence for Direct Interaction between Sprouty and Cbl

2001 • 127 citations

Dual function of the region-specific homeotic gene spalt during Drosophila tracheal system development

1996 • 126 citations

Grainy head controls apical membrane growth and tube elongation in response to Branchless/FGF signalling

2002 • 126 citations

Genetic dissection of pointed, a Drosophila gene encoding two ETS-related proteins.

1993 • 124 citations

The transcription factors KNIRPS and KNIRPS RELATED control cell migration and branch morphogenesis during Drosophila tracheal development

1998 • 122 citations

Drosophila Heparan Sulfate 6-O-Sulfotransferase (dHS6ST) Gene

2001 • 121 citations

Interplay of Notch and FGF signaling restricts cell fate and MAPK activation in the Drosophila trachea

1999 • 118 citations

The Nonreceptor Protein Tyrosine Phosphatase Corkscrew Functions in Multiple Receptor Tyrosine Kinase Pathways inDrosophila

1996 • 114 citations

The plakin Short Stop and the RhoA GTPase are required for E-cadherin-dependent apical surface remodeling during tracheal tube fusion

2002 • 112 citations

DPP controls tracheal cell migration along the dorsoventral body axis of the Drosophila embryo

1997 • 108 citations

The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development

1994 • 107 citations

ventral veinless, the gene encoding the Cf1a transcription factor, links positional information and cell differentiation during embryonic and imaginal development in Drosophila melanogaster

1995 • 106 citations

The Physiology of Insect Tracheoles

1983 • 105 citations

Interactions between the EGF receptor and DPP pathways establish distinct cell fates in the tracheal placodes

1997 • 97 citations

members only encodes a Drosophila nucleoporin required for Rel protein import and immune response activation

2000 • 93 citations

Control of tracheal tubulogenesis by Wingless signaling

2000 • 91 citations

The Co-ordination of Growth in the Tracheal System of Insects

1958 • 91 citations

Breathless, a Drosophila FGF receptor homolog, is required for the onset of tracheal cell migration and tracheole formation

1995 • 91 citations

stumps, a Drosophila Gene Required for Fibroblast Growth Factor (FGF)-directed Migrations of Tracheal and Mesodermal Cells

1999 • 90 citations

A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila

2001 • 85 citations

Attractive and repulsive functions of Slit are mediated by different receptors in theDrosophilatrachea

2002 • 85 citations

wingless and its signalling pathway have common and separable functions during tracheal development

2000 • 83 citations

Translational readthrough in the hdc mRNA generates a novel branching inhibitor in the Drosophila trachea

1998 • 79 citations

The Notch pathway helps to pattern the tips of the Drosophila tracheal branches by selecting cell fates

1999 • 75 citations

Genetic control of branching morphogenesis during Drosophila tracheal development

2000 • 71 citations

Tracheal development and the von Hippel–Lindau tumor suppressor homolog in Drosophila

2000 • 70 citations

ribbonencodes a novel BTB/POZ protein required for directed cell migration inDrosophila melanogaster

2001 • 70 citations

The Role of the Epidermal Cells in the ‘Migration’ of Tracheoles in Rhodnius Prolixus (Hemiptera)

1959 • 69 citations

ventral veinless, a POU domain transcription factor, regulates different transduction pathways required for tracheal branching in Drosophila

1997 • 67 citations

Dpp and Notch specify the fusion cell fate in the dorsal branches of the Drosophila trachea

1999 • 67 citations

Ligand-dependent activation of breathless FGF receptor gene in Drosophila developing trachea

2002 • 65 citations

Cross-regulatory interactions among tracheal genes support a co-operative model for the induction of tracheal fates in the Drosophila embryo

2000 • 65 citations

EGF signalling regulates cell invagination as well as cell migration during formation of tracheal system in Drosophila

1999 • 64 citations

Interaction between the bHLH-PAS protein Trachealess and the POU-domain protein Drifter, specifies tracheal cell fates

2000 • 62 citations

Cell fate choices in Drosophila tracheal morphogenesis

2000 • 62 citations

The tracheae defective gene encodes a bZIP protein that controls tracheal cell movement during Drosophila embryogenesis

1997 • 61 citations

Drosophila melanogaster SL2 cells contain a hypoxically inducible DNA binding complex which recognises mammalian HIF‐1 binding sites

1996 • 59 citations

Specific tracheal migration is mediated by complementary expression of cell surface proteins

2001 • 59 citations

TheDrosophila ribbongene encodes a nuclear BTB domain protein that promotes epithelial migration and morphogenesis

2001 • 57 citations

Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches

2002 • 56 citations

Function of the Drosophila POU domain transcription factor Drifter as an upstream regulator of Breathless receptor tyrosine kinase expression in developing trachea

1996 • 55 citations

Seven Wnt homologues in Drosophila : A case study of the developing tracheae

2001 • 54 citations

Control of Drosophila tracheal branching by the novel homeodomain gene unplugged, a regulatory target for genes of the bithorax complex

1995 • 53 citations

The hindsight Gene Is Required for Epithelial Maintenance and Differentiation of the Tracheal System in Drosophila

2000 • 44 citations

adrift, a novel bnl-induced Drosophila gene, required for tracheal pathfinding into the CNS

1999 • 42 citations

Specificity of FGF signaling in cell migration inDrosophila

2001 • 41 citations

Single mesodermal cells guide outgrowth of ectodermal tubular structures in Drosophila

2000 • 40 citations

Distinct Variant DNA-Binding Sites Determine Cell-Specific Autoregulated Expression of the Drosophila POU Domain Transcription Factor Drifter in Midline Glia or Trachea

1996 • 40 citations

Regulation of Drosophila Tracheal System Development by Protein Kinase B

2001 • 37 citations

Drosophila tracheal system formation involves FGF‐dependent cell extensions contacting bridge‐cells

2002 • 36 citations

spalt-Induced Specification of Distinct Dorsal and Ventral Domains Is Required for Drosophila Tracheal Patterning

2002 • 34 citations

The Alternative Migratory Pathways of the Drosophila Tracheal Cells Are Associated with Distinct Subsets of Mesodermal Cells

2000 • 33 citations

Hedgehog signaling patterns the tracheal branches

2001 • 31 citations

ThejingZn-finger transcription factor is a mediator of cellular differentiation in theDrosophilaCNS midline and trachea

2002 • 24 citations

Genes that control organ form: lessons from bone and branching morphogenesis.

1997 • 15 citations

Untitled

1997 • 12 citations

Stripe Provides Cues Synergizing with Branchless to Direct Tracheal Cell Migration

2002 • 11 citations

spalt-Induced Specification of Distinct Dorsal and Ventral Domains Is Required for Drosophila Tracheal Patterning

2002 • 3 citations