Interplay of Notch and FGF signaling restricts cell fate and MAPK activation in the Drosophila trachea

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Vasculogenesis

1995 • 1,344 citations

Notch Signaling

1995 • 1,282 citations

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

1997 • 1,239 citations

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

1997 • 1,121 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

The choice of cell fate in the epidermis of Drosophila

1991 • 736 citations

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

1990 • 675 citations

branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching

1996 • 631 citations

Fringe modulates Notch–ligand interactions

1997 • 578 citations

LIN-12/Notch signaling: lessons from worms and flies

1998 • 545 citations

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

1996 • 497 citations

On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster

1983 • 493 citations

Morphogenesis

1999 • 491 citations

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors.

1986 • 427 citations

In Situ Activation Pattern of Drosophila EGF Receptor Pathway During Development

1997 • 372 citations

Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing

1997 • 369 citations

Development of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events

1996 • 365 citations

Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation.

1996 • 316 citations

MAP kinase in situ activation atlas during Drosophila embryogenesis

1997 • 314 citations

Zygotic Drosophila E-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo.

1996 • 289 citations

A nuclear GFP/β‐galactosidase fusion protein as a marker for morphogenesis in living Drosophila

1996 • 269 citations

Delta, a Drosophila neurogenic gene, is transcriptionally complex and encodes a protein related to blood coagulation factors and epidermal growth factor of vertebrates.

1988 • 251 citations

The function of the neurogenic genes during epithelial development in the Drosophila embryo

1992 • 248 citations

Notch signalling mediates segmentation of the Drosophila leg

1998 • 223 citations

Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development

1993 • 222 citations

The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster.

1990 • 222 citations

Reciprocal localization of Nod and kinesin fusion proteins indicates microtubule polarity in the Drosophila oocyte, epithelium, neuron and muscle

1997 • 221 citations

The Drosophila FGF-R homolog is expressed in the embryonic tracheal system and appears to be required for directed tracheal cell extension.

1991 • 217 citations

The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation

1994 • 209 citations

Feedback regulation is central to Delta-Notch signalling required for Drosophila wing vein morphogenesis

1997 • 207 citations

The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system

1996 • 185 citations

The Drosophila gene Serrate encodes an EGF-like transmembrane protein with a complex expression pattern in embryos and wing discs

1991 • 179 citations

Notch signalling regulates veinlet expression and establishes boundaries between veins and interveins in the Drosophila wing

1997 • 178 citations

Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila

1998 • 177 citations

Genetic control of epithelial tube fusion during Drosophila tracheal development

1996 • 174 citations

Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor Escargot

1996 • 170 citations

The involvement of the Notch locus in Drosophila oogenesis

1992 • 166 citations

Identification of a Drosophila homologue of alpha-catenin and its association with the armadillo protein.

1993 • 161 citations

Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration.

1994 • 156 citations

The Expression of Neurogenic Loci in Imaginal Epidermal Cells of Drosophila Melanogaster

1984 • 146 citations

Transcriptional regulation of breathless FGF receptor gene by binding of TRACHEALESS/dARNT heterodimers to three central midline elements in Drosophila developing trachea

1997 • 134 citations

The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes

1992 • 127 citations

Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot.

1994 • 124 citations

The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development

1994 • 107 citations

Generating lineage‐specific markers to study Drosophila development

1991 • 101 citations

Control of imaginal cell development by the escargot gene of Drosophila

1993 • 100 citations

Control of imaginal cell development by the escargot gene of Drosophila

1993 • 83 citations

The Notch pathway helps to pattern the tips of the Drosophila tracheal branches by selecting cell fates

1999 • 75 citations

The pleiotropic function of Delta during postembryonic development of Drosophila melanogaster.

1993 • 74 citations

The pattern of transcription of the neurogenic gene Delta of Drosophila melanogaster

1990 • 72 citations

Proto‐oncogene of int‐3, a mouse Notch homologue, is expressed in endothelial cells during early embryogenesis

1997 • 70 citations

Understanding mammary gland development through the imbalanced expression of growth regulators

1996 • 25 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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