Drosophila Heparan Sulfate 6-O-Sulfotransferase (dHS6ST) Gene

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

1995 • 5,971 citations

Mechanisms of angiogenesis

1997 • 5,696 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

DEVELOPMENT IN DROSOPHILA MELANOGASTER

1927 • 2,909 citations

Angiogenesis.

1992 • 2,581 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

1991 • 2,437 citations

Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis

1999 • 1,291 citations

Crystal Structure of a Ternary FGF-FGFR-Heparin Complex Reveals a Dual Role for Heparin in FGFR Binding and Dimerization

2000 • 1,146 citations

Use of dsRNA-Mediated Genetic Interference to Demonstrate that frizzled and frizzled 2 Act in the Wingless Pathway

1998 • 1,116 citations

Comparison of the consensus sequence flanking translational start sites inDrosophilaand vertebrates

1987 • 966 citations

Heparin Structure and Interactions with Basic Fibroblast Growth Factor

1996 • 789 citations

branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching

1996 • 631 citations

Structural Basis for FGF Receptor Dimerization and Activation

1999 • 597 citations

Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4.

1993 • 542 citations

An Essential Heparin-Binding Domain in the Fibroblast Growth Factor Receptor Kinase

1993 • 520 citations

The downstream core promoter element, DPE, is conserved fromDrosophila to humans and is recognized by TAF_II60 of Drosophila

1997 • 487 citations

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

1999 • 474 citations

Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22

1986 • 455 citations

Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase

1998 • 453 citations

Heparan sulfate: a piece of information

1996 • 441 citations

Two-color whole-mount in situ hybridization to vertebrate and Drosophila embryos

1994 • 438 citations

Integral membrane heparan sulfate proteoglycans

1993 • 423 citations

breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells.

1992 • 419 citations

In Situ Activation Pattern of Drosophila EGF Receptor Pathway During Development

1997 • 372 citations

Hedgehog Movement Is Regulated through tout velu–Dependent Synthesis of a Heparan Sulfate Proteoglycan

1999 • 367 citations

Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development

1999 • 367 citations

Control of cell lineage-specific development and transcription by bHLH-PAS proteins

1998 • 347 citations

Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions

1997 • 324 citations

MAP kinase in situ activation atlas during Drosophila embryogenesis

1997 • 314 citations

Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages.

1996 • 303 citations

Structural Analysis of Glycosaminoglycans inDrosophila and Caenorhabditis elegans and Demonstration That tout-velu, a Drosophila Gene Related to EXT Tumor Suppressors, Affects Heparan Sulfate in Vivo

2000 • 287 citations

Miranda Is Required for the Asymmetric Localization of Prospero during Mitosis in Drosophila

1997 • 284 citations

Heparan Sulfate Oligosaccharides Require 6-O-Sulfation for Promotion of Basic Fibroblast Growth Factor Mitogenic Activity

1998 • 276 citations

Tubulogenesis in Drosophila: a requirement for the trachealess gene product.

1996 • 264 citations

trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila.

1996 • 264 citations

The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the TargetedN-Sulfoglucosamine

2000 • 223 citations

Spatially Restricted Expression of pipe in the Drosophila Egg Chamber Defines Embryonic Dorsal–Ventral Polarity

1998 • 208 citations

TFIID sequence recognition of the initiator and sequences farther downstream in Drosophila class II genes.

1994 • 207 citations

Selectively Desulfated Heparin Inhibits Fibroblast Growth Factor-induced Mitogenicity and Angiogenesis

2000 • 174 citations

Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor

1992 • 173 citations

Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor Escargot

1996 • 170 citations

Structural Analysis of Glycosaminoglycans in Animals Bearing Mutations in sugarless, sulfateless, andtout-velu

2000 • 156 citations

Regulated Breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system.

1996 • 146 citations

Transcriptional regulation of breathless FGF receptor gene by binding of TRACHEALESS/dARNT heterodimers to three central midline elements in Drosophila developing trachea

1997 • 134 citations

Promoter elements in Drosophila melanogaster revealed by sequence analysis.

1995 • 120 citations

Generating lineage‐specific markers to study Drosophila development

1991 • 101 citations

Molecular Characterization and Expression of Heparan-sulfate 6-Sulfotransferase

1998 • 101 citations

Purification and Characterization of Heparan Sulfate 6-Sulfotransferase from the Culture Medium of Chinese Hamster Ovary Cells

1995 • 87 citations

A role of Lys⁶¹⁴ in the sulfotransferase activity of human heparan sulfate N‐deacetylase/N‐sulfotransferase

1998 • 55 citations

Stimulation of glycosaminoglycan sulfotransferase from chick embryo cartilage by basic proteins and polyamines

1980 • 37 citations

Preparation and high-performance liquid chromatography of 3′-phosphoadenosine-5′-phospho[35S]sulfate with a predetermined specific activity

1985 • 36 citations

Distinct expression of two Drosophila homologs of fibroblast growth factor receptors in imaginai discs

1993 • 19 citations

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