Expression Directed from HIV Long Terminal Repeats in the Central Nervous System of Transgenic Mice

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Detection of AIDS Virus in Macrophages in Brain Tissue from AIDS Patients with Encephalopathy

1986 • 1,694 citations

The AIDS dementia complex: I. Clinical features

1986 • 1,679 citations

A soluble protein characteristic of the nervous system

1965 • 1,678 citations

The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex

1988 • 1,244 citations

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.

1986 • 1,242 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

Isolation of HTLV-III from Cerebrospinal Fluid and Neural Tissues of Patients with Neurologic Syndromes Related to the Acquired Immunodeficiency Syndrome

1985 • 1,103 citations

Selective Tropism of Lymphadenopathy Associated Virus (LAV) for Helper-Inducer T Lymphocytes

1984 • 976 citations

Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA

1984 • 973 citations

Dual Infection of the Central Nervous System by AIDS Viruses with Distinct Cellular Tropisms

1987 • 831 citations

The Reservoir for HIV-1 in Human Peripheral Blood Is a T Cell That Maintains Expression of CD4

1989 • 732 citations

Genetic Variation in HTLV-III/LAV Over Time in Patients with AIDS or at Risk for AIDS

1986 • 570 citations

The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice

1988 • 532 citations

Inhibition of Entry of HIV-1 in Neural Cell Lines by Antibodies Against Galactosyl Ceramide

1991 • 523 citations

Neocortical damage during HIV infection

1991 • 456 citations

Extensive variation of human immunodeficiency virus type-1 in vivo

1988 • 415 citations

Soluble CD4 blocks the infectivity of diverse strains of HIV and SIV for T cells and monocytes but not for brain and muscle cells

1989 • 405 citations

Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes

1991 • 385 citations

Loss of neurons in the frontal cortex in AIDS brains

1990 • 355 citations

ISOLATION OF AIDS-ASSOCIATED RETROVIRUSES FROM CEREBROSPINAL FLUID AND BRAIN OF PATIENTS WITH NEUROLOGICAL SYMPTOMS

1985 • 345 citations

Determination of the leukaemogenicity of a murine retrovirus by sequences within the long terminal repeat

1984 • 321 citations

Brain pathology induced by infection with the human immunodeficiency virus (HIV)

1987 • 315 citations

Human immunodeficiency virus can productively infect cultured human glial cells.

1987 • 307 citations

CD4-independent infection of human neural cells by human immunodeficiency virus type 1

1989 • 297 citations

HIV antigen in the brains of patients with the AIDS dementia complex

1987 • 289 citations

AIDS subacute encephalitis. Identification of HIV-infected cells.

1987 • 286 citations

VIP: Molecular biology and neurobiological function

1989 • 249 citations

Human T-cell lymphotropic virus type III infection of the central nervous system. A preliminary in situ analysis

1986 • 238 citations

Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus.

1989 • 233 citations

Morphology and distribution of HIV-1 gp41-positive microglia in subacute AIDS encephalitis

1990 • 212 citations

A specific histochemical marker (lectinRicinus communis agglutinin-1) for normal human microglia, and application to routine histopathology

1986 • 208 citations

Development of Disease and Virus Recovery in Transgenic Mice Containing HIV Proviral DNA

1988 • 185 citations

Human Immunodeficiency Virus in Brain Biopsies of Patients with AIDS and Progressive Encephalopathy

1987 • 176 citations

Immunohistochemical localization of human and simian immunodeficiency viral antigens in fixed tissue sections.

1987 • 170 citations

Human T-Cell Lymphotropic Virus Type III Infection of the Central Nervous System

1986 • 154 citations

Tissue-Specific Expression in Transgenic Mice of a Fused Gene Containing RSV Terminal Sequences

1986 • 154 citations

The adrenal cortex and rheumatoid arthritis.

1951 • 146 citations

Microglia in the giant cell encephalitis of acquired immune deficiency syndrome: proliferation, infection and fusion

1988 • 140 citations

Naturally occurring mutations within HIV-1 V3 genomic RNA lead to antigenic variation dependent on a single amino acid substitution

1991 • 140 citations

CD4-independent, productive infection of a neuronal cell line by human immunodeficiency virus type 1

1990 • 137 citations

Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines.

1987 • 132 citations

Tissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequences

1985 • 130 citations

Human immunodeficiency virus type 1 in spinal cords of acquired immunodeficiency syndrome patients with myelopathy: expression and replication in macrophages.

1989 • 128 citations

Prominent cortical atrophy with neuronal loss as correlate of human immunodeficiency virus encephalopathy

1991 • 67 citations

Infection of human fetal dorsal root ganglion glial cells with human immunodeficiency virus type 1 involves an entry mechanism independent of the CD4 T4A epitope

1989 • 65 citations

NON-CYTOCIDAL NATURAL VARIANTS OF HUMAN IMMUNODEFICIENCY VIRUS ISOLATED FROM AIDS PATIENTS WITH NEUROLOGICAL DISORDERS

1987 • 64 citations

The Human Immunodeficiency Virus Long Terminal Repeat Is Preferentially Expressed in Langerhans Cells in Transgenic Mice

1989 • 64 citations

The visna virus long terminal repeat directs expression of a reporter gene in activated macrophages, lymphocytes, and the central nervous systems of transgenic mice

1989 • 58 citations

Construction of recombinants between molecular clones of murine retrovirus MCF 247 and Akv: determinant of an in vitro host range property that maps in the long terminal repeat

1985 • 44 citations

HIV replicates in cultured human brain cells.

1987 • 39 citations

The long terminal repeat is not a major determinant of the cellular tropism of human immunodeficiency virus type 1

1991 • 36 citations

Examination of brains of AIDS cases for human immunodeficiency virus and human cytomegalovirus nucleic acids.

1989 • 19 citations

Expression of a human immunodeficiency virus type 1 long terminal repeat/simian virus 40 early region fusion gene in transgenic mice

1991 • 14 citations