Shared usage of the chemokine receptor CXCR4 by the feline and human immunodeficiency viruses

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

Amino acid substitution matrices from protein blocks.

1992 • 5,998 citations

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

1996 • 2,735 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

1996 • 2,326 citations

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase.

1986 • 2,118 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1996 • 1,973 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1996 • 1,678 citations

CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5

1996 • 1,058 citations

Identification of the Envelope V3 Loop as the Primary Determinant of Cell Tropism in HIV-1

1991 • 871 citations

CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

1996 • 669 citations

Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp!20 gene

1991 • 525 citations

Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution

1992 • 501 citations

High efficiency gene transfer into mammalian cells

1984 • 498 citations

Primary, syncytium-inducing human immunodeficiency virus type 1 isolates are dual-tropic and most can use either Lestr or CCR5 as coreceptors for virus entry

1996 • 365 citations

A seven-transmembrane domain receptor involved in fusion and entry of T-cell-tropic human immunodeficiency virus type 1 strains

1996 • 348 citations

Fusogenic mechanisms of enveloped-virus glycoproteins analyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusion-dependent reporter gene activation

1994 • 343 citations

Small amino acid changes in the V3 hypervariable region of gp120 can affect the T-cell-line and macrophage tropism of human immunodeficiency virus type 1.

1992 • 317 citations

Immunologic abnormalities in pathogen-free cats experimentally infected with feline immunodeficiency virus

1990 • 291 citations

Specific cell surface requirements for the infection of CD4-positive cells by human immunodeficiency virus types 1 and 2 and by simian immunodeficiency virus

1991 • 257 citations

In vivo lymphocyte tropism of feline immunodeficiency virus

1993 • 201 citations

Feline immunodeficiency virus: a neurotropic lentivirus.

1990 • 186 citations

Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent

1997 • 183 citations

Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity

1997 • 177 citations

Molecular cloning of feline immunodeficiency virus.

1989 • 167 citations

Infection of peritoneal macrophages in vitro and in vivo with feline immunodeficiency virus

1989 • 149 citations

Establishment of a feline T-lymphoblastoid cell line highly sensitive for replication of feline immunodeficiency virus

1989 • 144 citations

Lymphocyte population changes in cats naturally infected with feline immunodeficiency virus

1990 • 139 citations

Frequent infection of peripheral blood CD8-positive T-lymphocytes with HIV-1

1996 • 124 citations

Proviral burden and infection kinetics of feline immunodeficiency virus in lymphocyte subsets of blood and lymph node

1996 • 102 citations

A single mutation within the V3 envelope neutralization domain of feline immunodeficiency virus determines its tropism for CRFK cells

1995 • 80 citations

The CD4-independent tropism of human immunodeficiency virus type 2 involves several regions of the envelope protein and correlates with a reduced activation threshold for envelope-mediated fusion

1997 • 79 citations

Impairment of T Cell Receptor-Dependent Stimulation in CD4+ Lymphocytes after Contact with Membrane-Bound HIV-1 Envelope Glycoprotein

1994 • 78 citations

HIV-2 and SIV Infection of Nonprimate Cell Lines Expressing Human CD4: Restrictions to Replication at Distinct Stages

1994 • 71 citations

Productive infection of T-helper lymphocytes with feline immunodeficiency virus is accompanied by reduced expression of CD4

1991 • 65 citations

A monoclonal antibody which blocks infection with feline immunodeficiency virus identifies a possible non-CD4 receptor

1993 • 61 citations

The "V3" domain is a determinant of simian immunodeficiency virus cell tropism

1994 • 54 citations

Inhibition of feline immunodeficiency virus infection by CD9 antibody operates after virus entry and is independent of virus tropism.

1997 • 47 citations

A determinant of feline immunodeficiency virus involved in Crandell feline kidney cell tropism

1995 • 45 citations

Radiocarbon dating evidence on the impact of atmospheric pollution on upland peats

1979 • 42 citations

Virus neutralization reveals antigenic variation among feline immunodeficiency virus isolates

1994 • 41 citations

Feline immunodeficiency virus can infect a human cell line (MOLT-4) but establishes a state of latency in the cells

1996 • 40 citations

Differences in Feline Immunodeficiency Virus Host Cell Range Correlate with Envelope Fusogenic Properties

1995 • 37 citations

Simian immunodeficiency virus infection of CD8+ lymphocytes in vivo

1996 • 36 citations

Spontaneous substitutions in the vicinity of the V3 analog affect cell tropism and pathogenicity of simian immunodeficiency virus

1994 • 34 citations

Suppression of virus burden by immunization with feline immunodeficiency virus Env protein

1996 • 31 citations

Humoral and Cytotoxic T Cell Immune Responses to Internal and External Structural Proteins of Simian Virus 5 Induced by Immunization with Solid Matrix-Antibody-Antigen Complexes

1988 • 30 citations

Feline CD 4 molecules expressed on feline non-lymphoid cell lines are not enough for productive infection of highly lymphotropic feline immunodeficiency virus isolates

1993 • 30 citations

cDNA cloning and eukaryotic expression of feline CD9

1995 • 17 citations