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beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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Clinical trial of indomethacin in Alzheimer's disease

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β-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease

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Calcium-destabilizing and neurodegenerative effects of aggregated β-amyloid peptide are attenuated by basic FGF

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Functions and mechanisms of interleukin 1 in the brain

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β-Amyloid stimulates glial cells in vitro to produce growth factors that accumulate in senile plaques in Alzheimer's disease

1992 • 291 citations

Is amyloidogenesis during Alzheimer's disease due to an IL-1-/IL-6-mediated ‘acute phase response’ in the brain?

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1989 • 233 citations

IL-1 and TNF-alpha induction of IL-8 and monocyte chemotactic and activating factor (MCAF) mRNA expression in a human astrocytoma cell line.

1991 • 166 citations

Neuroimmune Mechanisms in Alzheimer Disease Pathogenesis

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Synthetic Alzheimer amyloid β/A4 peptides enhance production of complement C3 component by cultured microglial cells

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Neurotoxicity of Human Amylin in Rat Primary Hippocampal Cultures: Similarity to Alzheimer's Disease Amyloid‐β Neurotoxicity

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β-amyloid peptide in vitro toxicity: Lot-to-lot variability

1992 • 116 citations

Astroglia in Alzheimer's disease

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Cerebral amyloidosis, ageing and Alzheimer's disease; A contribution from studies on Down's syndrome

1989 • 112 citations

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1994 • 105 citations

Interleukin-6 secretion from human astrocytoma cells induced by substance P

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Interleukin-1β increases synaptic inhibition in rat hippocampal pyramidal neurons in vitro

1992 • 74 citations

Interleukin‐1 and tumor necrosis factor‐mediated regulation of C3 gene expression in human astroglioma cells

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Regulation of the Release of Interleukin‐6 from Human Astrocytoma Cells

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Dexamethasone regulation of the expression of cytokine mRNAs induced by interleukin‐1 in the astrocytoma cell line U373MG

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Chapter 38: The involvement of astrocytes and an acute phase response in the amyloid deposition of Alzheimer's disease

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Calcium ionophore A23187 induces interleukin‐8 gene expression and protein secretion in human monocytic cells

1993 • 32 citations

Neuronal membrane conductance activated by amyloid β peptide: importance of peptide conformation

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