Effect of antioxidants, resveratrol, quercetin, andN-acetylcysteine, on the functions of cultured rat hepatic stellate cells and kupffer cells

Cancer Cell Cycles

1996 • 5,379 citations

Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

1997 • 4,867 citations

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

NF-κB: Ten Years After

1996 • 3,008 citations

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

Cyclins and cancer II: Cyclin D and CDK inhibitors come of age

1994 • 2,122 citations

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1994 • 1,999 citations

SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins

1991 • 1,931 citations

Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine

1993 • 1,665 citations

The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

1993 • 1,444 citations

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase).

1991 • 1,041 citations

Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

1989 • 978 citations

Biologically active products of stimulated liver macrophages (Kupffer cells)

1990 • 926 citations

The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease

1995 • 885 citations

Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression.

1992 • 653 citations

Phospholipid signaling

1995 • 561 citations

Requirement for MAP Kinase (ERK2) Activity in Interferon α- and Interferon β-Stimulated Gene Expression Through STAT Proteins

1995 • 549 citations

Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression.

1995 • 536 citations

Cell Cycle Control of DNA Replication

1996 • 512 citations

N-Acetylcystei ne: Pharmacological Considerations and Experimental and Clinical Applications

1996 • 448 citations

Differential Activation of Mitogen-Activated Protein Kinases by H ₂ O ₂ and O ₂ ⁻ in Vascular Smooth Muscle Cells

1995 • 416 citations

The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances

1993 • 391 citations

Dimerization of B-type Platelet-derived Growth Factor Receptors Occurs After Ligand Binding and Is Closely Associated with Receptor Kinase Activation

1989 • 366 citations

Viewpoint: Putting the Cell Cycle in Order

1996 • 357 citations

Book Review Ethical Problems in Dialysis and Transplantation (Developments in Nephrology. Vol. 33.) Edited by Carl M. Kjellstrand and John B. Dossetor. 235 pp., illustrated. Boston, Kluwer Academic, 1992. $108.50. 0-7923-1625-8

1993 • 329 citations

Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture.

1994 • 300 citations

Beyond alcohol: Beverage consumption and cardiovascular mortality

1995 • 294 citations

Expression of the gene of the α-smooth muscle-actin isoform in rat liver and in rat fat-storing (ITO) cells

1990 • 283 citations

Ordering the Cell Death Pathway

1996 • 231 citations

Cytokines and cellular crosstalk involved in the activation of fat-storing cells.

1995 • 224 citations

The stellate cell (Ito-cell, fat-storing cell, lipocyte, perisinusoidal cell) of the liver

1992 • 212 citations

Ligand-induced dimerization of the platelet-derived growth factor receptor

1989 • 190 citations

Inhibition of rat hepatic lipocyte activation in culture by interferon-γ

1992 • 185 citations

Interferon alfa and gamma inhibit proliferation and collagen synthesis of human ito cells in culture

1995 • 181 citations

Novel insights into the biology and physiology of the Ito cell

1995 • 181 citations

Differential Stimulation of ERK and JNK Activities by Ultraviolet B Irradiation and Epidermal Growth Factor in Human Keratinocytes

1997 • 150 citations

Molecular and cellular aspects of iron-induced hepatic cirrhosis in rodents.

1995 • 138 citations

N-acetylcysteine and alpha-tocopherol reverse the inflammatory response in activated rat Kupffer cells.

1997 • 81 citations

Interferon-gamma-mediated activation of STAT1alpha regulates growth factor-induced mitogenesis.

1996 • 76 citations

Regulation of platelet-derived growth factor secretion and gene expression in human liver fat-storing cells

1994 • 67 citations

Liver transplantation: Viral hepatitis

1995 • 59 citations

Acetaldehyde regulates the gene expression of matrix-metalloproteinase-1 and -2 in human fat-storing cells

1994 • 47 citations

[17] Redox regulation of activation of NF-κB transcription factor complex: Effects of N-acetylcysteine

1995 • 45 citations

Regulation of Differentiated Phenotype of Rat Hepatic Lipocytes by Retinoids in Primary Culture

1995 • 41 citations

Closing in on the signals of hepatic fibrosis

1997 • 37 citations

Induction of ?-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture Wong L, Yamasaki G, Johnson RL, Friedman SL. J Clin Invest 1994;94:1563?1569

1995 • 35 citations

Inhibition of myofibroblastic transformation of cultured rat hepatic stellate cells by methylxanthines and dibutyryl cAMP

1996 • 32 citations

Effect of pentoxifylline on the fibrogenic functions of cultured rat liver fat-storing cells and myofibroblasts

1996 • 32 citations

Efficacy of N-acetylcysteine as a hepatoprotective agent in liver transplantation: An experimental study

1997 • 29 citations

Glutathione regulation in rat hepatic stellate cells

1997 • 21 citations

Prostaglandin E suppression of platelet-derived-growth-factor-induced Ito cell mitogenesis occurs independent of raf perinuclear translocation and nuclear proto-oncogene expression

1994 • 17 citations

Mechanism that regulates nitric oxide production by lipopolysaccharide-stimulated rat Kupffer cells.

1996 • 11 citations

Regulation of Alpha‐Smooth Muscle Actin Expression in Adult Cardiomyocytes through a Tyrosine Kinase Signal Transduction Pathway^a

1995 • 4 citations