Transcriptional Regulators of the Schizosaccharomyces pombe fbp1 Gene Include Two Redundant Tup1p-like Corepressors and the CCAAT Binding Factor Activation Complex

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1994 • 63,397 citations

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformaion of Escherichia coli

1987 • 2,493 citations

Heterologous modules for efficient and versatile PCR-based gene targeting inSchizosaccharomyces pombe

1998 • 2,230 citations

Transcriptional activation by recruitment

1997 • 1,163 citations

The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE).

1996 • 1,050 citations

Cyclic AMP and the induction of eukaryotic gene transcription.

1988 • 1,041 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Yeast MIG1 repressor is related to the mammalian early growth response and Wilms' tumour finger proteins.

1990 • 488 citations

Msn2p, a zinc finger DNA-binding protein, is the transcriptional activator of the multistress response in Saccharomyces cerevisiae.

1996 • 476 citations

Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast

1995 • 474 citations

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

1996 • 460 citations

Identification and characterization of HAP4: a third component of the CCAAT-bound HAP2/HAP3 heteromer.

1989 • 432 citations

Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast.

1996 • 419 citations

Regulation of gene expression by oxygen in Saccharomyces cerevisiae

1992 • 404 citations

The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.

1996 • 365 citations

Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast.

1995 • 356 citations

Glucose repression in the yeast Saccharomyces cerevisiae

1992 • 347 citations

Functional dissection of the yeast Cyc8–Tupl transcriptional co-repressor complex

1994 • 338 citations

Activation and Regulation of the Spc1 Stress-Activated Protein Kinase in Schizosaccharomyces pombe

1996 • 300 citations

Cloning of yeast HAP5: a novel subunit of a heterotrimeric complex required for CCAAT binding.

1995 • 276 citations

A family of immunologically related transcription factors that includes multiple forms of ATF and AP-1.

1988 • 259 citations

Distinct TPR motifs of Cyc8 are involved in recruiting the Cyc8-Tup1 corepressor complex to differentially regulated promoters.

1995 • 258 citations

Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase.

1995 • 257 citations

Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site, UAS2, in an interdependent manner

1987 • 255 citations

Transcriptional Coregulators in Development

1999 • 242 citations

DNA damage and cell cycle regulation of ribonucleotide reductase

1993 • 241 citations

Importance of a Flanking AT-Rich Region in Target Site Recognition by the GC Box-Binding Zinc Finger Protein MIGl

1994 • 219 citations

Two Homologous Zinc Finger Genes Identified by Multicopy Suppression in a SNF1 Protein Kinase Mutant of Saccharomyces cerevisiae

1993 • 218 citations

The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex.

1991 • 216 citations

Molecular analysis of SSN6, a gene functionally related to the SNF1 protein kinase of Saccharomyces cerevisiae.

1987 • 192 citations

The S.pombe mei2 gene encoding a crucial molecule for commitment to meiosis is under the regulation of cAMP.

1988 • 187 citations

Characterization of Three Related Glucose Repressors and Genes They Regulate in Saccharomyces cerevisiae

1998 • 182 citations

The Mcs4 response regulator coordinately controls the stress-activated Wak1-Wis1-Sty1 MAP kinase pathway and fission yeast cell cycle.

1997 • 181 citations

Repressors and Upstream Repressing Sequences of the Stress-Regulated ENA1 Gene in Saccharomyces cerevisiae: bZIP Protein Sko1p Confers HOG-Dependent Osmotic Regulation

1999 • 181 citations

Discrete Roles of the Spc1 Kinase and the Atf1 Transcription Factor in the UV Response of Schizosaccharomyces pombe

1997 • 176 citations

YEAST TRANSCRIPTIONAL REGULATORY MECHANISMS

1995 • 173 citations

Two homologous zinc finger genes identified by multicopy suppression in a SNF1 protein kinase mutant of Saccharomyces cerevisiae.

1993 • 162 citations

Two Zinc-Finger-Containing Repressors Are Responsible for Glucose Repression of SUC2 Expression

1996 • 162 citations

Characterization of a fission yeast gene, gpa2, that encodes a G alpha subunit involved in the monitoring of nutrition.

1992 • 159 citations

Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway.

1991 • 154 citations

Cloning of the pka1 gene encoding the catalytic subunit of the cAMP-dependent protein kinase in Schizosaccharomyces pombe

1994 • 150 citations

Importance of a flanking AT-rich region in target site recognition by the GC box-binding zinc finger protein MIG1.

1994 • 144 citations

Adenylyl cyclase is dispensable for vegetative cell growth in the fission yeast Schizosaccharomyces pombe.

1990 • 137 citations

Glucose Monitoring in Fission Yeast via the gpa2 Gα, the git5 Gβ and the git3 Putative Glucose Receptor

2000 • 135 citations

The wis1 protein kinase is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombe.

1991 • 133 citations

Multiple modes of activation of the stress-responsive MAP kinase pathway in fission yeast

1997 • 131 citations

Schizosaccharomyces pombe gad7⁺ encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation

1996 • 130 citations

Mcs4 mitotic catastrophe suppressor regulates the fission yeast cell cycle through the Wik1-Wis1-Spc1 kinase cascade.

1997 • 129 citations

The N-terminal TPR region is the functional domain of SSN6, a nuclear phosphoprotein of Saccharomyces cerevisiae.

1990 • 124 citations

Schizosaccharomyces pombe pcr1⁺ Encodes a CREB/ATF Protein Involved in Regulation of Gene Expression for Sexual Development

1996 • 116 citations

Nrg1 Is a Transcriptional Repressor for Glucose Repression ofSTA1Gene Expression inSaccharomyces cerevisiae

1999 • 110 citations

Hrs1/Med3 Is a Cyc8-Tup1 Corepressor Target in the RNA Polymerase II Holoenzyme

2000 • 105 citations

Isolation and characterization of mutants constitutive for expression of the fbp1 gene of Schizosaccharomyces pombe.

1990 • 104 citations

The Saccharomyces cerevisiae Hap5p Homolog from Fission Yeast Reveals Two Conserved Domains That Are Essential for Assembly of Heterotetrameric CCAAT-Binding Factor

1997 • 84 citations

Six git genes encode a glucose-induced adenylate cyclase activation pathway in the fission yeast Schizosaccharomyces pombe

1993 • 82 citations

AAR1/TUP1 Protein, with a Structure Similar to That of the β Subunit of G Proteins, Is Required for a1-α2 and α2 Repression in Cell Type Control of Saccharomyces cerevisiae

1991 • 82 citations

sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase.

1995 • 81 citations

The organized chromatin domain of the repressed yeast a cell-specific gene STE6 contains two molecules of the corepressor Tup1p per nucleosome

2000 • 77 citations

Protein Kinase A and Mitogen-Activated Protein Kinase Pathways Antagonistically Regulate Fission Yeast fbp1 Transcription by Employing Different Modes of Action at Two Upstream Activation Sites

2000 • 77 citations

The wis1 signal transduction pathway is required for expression of cAMP-repressed genes in fission yeast

1996 • 76 citations

A transcriptionally regulated expression vector for the fission yeast Schizosaccharomyces pombe

1989 • 75 citations

The Schizosaccharomyces pombe homolog of Saccharomyces cerevisiae HAP2 reveals selective and stringent conservation of the small essential core protein domain.

1991 • 74 citations

The Ssn6-Tup1 repressor complex of Saccharomyces cerevisiae is involved in the osmotic induction of HOG-dependent and -independent genes

1998 • 69 citations

The Fission Yeast Mitotic Regulatorwin1⁺Encodes an MAP Kinase Kinase Kinase That Phosphorylates and Activates Wis1 MAP Kinase Kinase in Response to High Osmolarity

1998 • 67 citations

Isolation and Characterization of an Invertase and Its Repressor Genes fromSchizosaccharomyces pombe

1998 • 61 citations

Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein alpha subunit encoded by gpa2 (git8).

1994 • 60 citations

Regulation of the Mts1-Mts2-Dependentade6-M26 Meiotic Recombination Hot Spot and Developmental Decisions by the Spc1 Mitogen-Activated Protein Kinase of Fission Yeast

1998 • 56 citations

Flocculation of Saccharomyces cerevisiae tup1 mutants

1984 • 52 citations

Isolation of the fructose-1,6-bisphosphatase gene of the yeast Schizosaccharomyces pombe. Evidence for transcriptional regulation.

1985 • 52 citations

The Fission Yeast git5 Gene Encodes a Gβ Subunit Required for Glucose-Triggered Adenylate Cyclase Activation

2000 • 51 citations

Onset of gluconate-H+ symport in Schizosaccharomyces pombe is regulated by the kinases Wis1 and Pka1, and requires the gti1+ gene product

1997 • 48 citations

Multiple regulatory proteins mediate repression and activation by interaction with the yeast Mig1 binding site

1998 • 47 citations

AAR1/TUP1 protein, with a structure similar to that of the beta subunit of G proteins, is required for a1-alpha 2 and alpha 2 repression in cell type control of Saccharomyces cerevisiae.

1991 • 42 citations

Conservation of Histone Binding and Transcriptional Repressor Functions in aSchizosaccharomyces pombeTup1p Homolog

1999 • 40 citations

The Schizosaccharomyces pombe pyp1 protein tyrosine phosphatase negatively regulates nutrient monitoring pathways

1996 • 37 citations

Gene Regulation by the Yeast Ssn6-Tup1 Corepressor

1998 • 36 citations

In Vivo Functions of Histone Acetylation/Deacetylation in Tup1p Repression and Gcn5p Activation

1998 • 34 citations

A sequence resembling a peroxisomal targeting sequence directs the interaction between the tetratricopeptide repeats of Ssn6 and the homeodomain of α2

2000 • 17 citations