Cell-cycle control linked to extracellular environment by MAP kinase pathway in fission yeast

[56] Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

1991 • 3,691 citations

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

1994 • 2,659 citations

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1994 • 1,684 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

1993 • 1,169 citations

A two-component system that regulates an osmosensing MAP kinase cascade in yeast

1994 • 1,091 citations

The MAP kinase cascade is essential for diverse signal transduction pathways

1993 • 1,091 citations

Thiamine-repressible expression vectors pREP and pRIP for fission yeast

1993 • 1,013 citations

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

1994 • 1,005 citations

mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2

1991 • 688 citations

Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines

1995 • 363 citations

Pyp1 and Pyp2 PTPases dephosphorylate an osmosensing MAP kinase controlling cell size at division in fission yeast.

1995 • 356 citations

The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts.

1993 • 305 citations

The decision to enter mitosis

1994 • 270 citations

A conserved kinase cascade for MAP kinase activation in yeast

1993 • 255 citations

MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae.

1994 • 241 citations

Counteractive roles of protein phosphatase 2C (PP2C) and a MAP kinase kinase homolog in the osmoregulation of fission yeast.

1995 • 192 citations

Dephosphorylation and inactivation of the mitogen-activated protein kinase by a mitogen-induced Thr/Tyr protein phosphatase

1993 • 170 citations

Nim1 kinase promotes mitosis by inactivating Wee1 tyrosine kinase

1993 • 161 citations

The wis1 protein kinase is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombe.

1991 • 133 citations

Evidence for communication between nerve growth factor and protein tyrosine phosphorylation

1990 • 107 citations

Protein phosphatase 2C, encoded by ptc1+, is important in the heat shock response of Schizosaccharomyces pombe.

1994 • 70 citations

Negative regulation of mitosis by two functionally overlapping PTPases in fission yeast.

1992 • 66 citations

The fission yeast genes pyp1+ and pyp2+ encode protein tyrosine phosphatases that negatively regulate mitosis.

1992 • 50 citations

Negative regulation of mitosis in fission yeast by catalytically inactive pyp1 and pyp2 mutants.

1994 • 18 citations