Negative Regulation of T Cell Proliferation and Interleukin 2 Production by the Serine Threonine Kinase Gsk-3

CD28/B7 SYSTEM OF T CELL COSTIMULATION

1996 • 2,726 citations

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

A molecular mechanism for the effect of lithium on development.

1996 • 2,270 citations

Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells

1996 • 1,299 citations

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

1989 • 1,010 citations

Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in insulin and growth-factor signalling

1993 • 877 citations

Nuclear Export of NF-ATc Enhanced by Glycogen Synthase Kinase-3

1997 • 754 citations

Versatile retroviral vectors for potential use in gene therapy.

1994 • 690 citations

CD5 Expression Is Developmentally Regulated By T Cell Receptor (TCR) Signals and TCR Avidity

1998 • 643 citations

Activation of the Wnt Signaling Pathway: A Molecular Mechanism for Lithium Action

1997 • 627 citations

Mitogen inactivation of glycogen synthase kinase-3β in intact cells via serine 9 phosphorylation

1994 • 578 citations

A Role for CD5 in TCR-Mediated Signal Transduction and Thymocyte Selection

1995 • 437 citations

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction.

1997 • 403 citations

Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

1996 • 396 citations

Direct Regulation of ZAP-70 by SHP-1 in T Cell Antigen Receptor Signaling

1996 • 390 citations

T cell antigen receptor signal transduction

1997 • 390 citations

Tissue Hyperplasia and Enhanced T-Cell Signalling via ZAP-70 in c-Cbl-Deficient Mice

1998 • 371 citations

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

1998 • 343 citations

DIFFERENTIAL SIGNALING BY LYMPHOCYTE ANTIGEN RECEPTORS

1997 • 273 citations

Cabin 1, A Negative Regulator for Calcineurin Signaling in T Lymphocytes

1998 • 235 citations

Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase.

1996 • 214 citations

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

1999 • 179 citations

Nucleocytoplasmic Shuttling Factors Including Ran and CRM1 Mediate Nuclear Export of NFAT In Vitro

1998 • 175 citations

Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness.

1996 • 174 citations

GSK3: a SHAGGY frog story

1996 • 150 citations

Mature T cell reactivity altered by peptide agonist that induces positive selection.

1996 • 148 citations

Dynamics of Oxidation of a Fe ²⁺ -Bearing Aluminosilicate (Basaltic) Melt

1996 • 148 citations

Csk controls antigen receptor-mediated development and selection of T-lineage cells

1998 • 138 citations

Structurally Related Receptors and Antagonists Compete for Secreted Wnt Ligands

1997 • 127 citations

The Dynamics of Protein Kinase B Regulation during B Cell Antigen Receptor Engagement

1999 • 124 citations

Regulation and functions of the glycogen synthase kinase-3 subfamily.

1994 • 103 citations

Tau phosphorylation in transgenic mice expressing glycogen synthase kinase-3β transgenes

1997 • 99 citations

T-cell Activation Leads to Rapid Stimulation of Translation Initiation Factor eIF2B and Inactivation of Glycogen Synthase Kinase-3

1996 • 95 citations

The tyrosine phosphatase SHP-1 influences thymocyte selection by setting TCR signaling thresholds

1999 • 77 citations

Degree of TCR Internalization and Ca2+ Flux Correlates with Thymocyte Selection

1998 • 50 citations

Prevention of autoimmune disease by retroviral-mediated gene therapy.

1995 • 45 citations