Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1)

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1990 • 2,129 citations

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

1994 • 685 citations

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase.

1992 • 629 citations

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.

1998 • 621 citations

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1994 • 621 citations

Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump.

1996 • 569 citations

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies.

1986 • 561 citations

Multidrug Resistance Protein (MRP)-mediated Transport of Leukotriene C4 and Chemotherapeutic Agents in Membrane Vesicles

1996 • 555 citations

ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein.

1994 • 435 citations

Structural, mechanistic and clinical aspects of MRP1

1999 • 408 citations

Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione.

1998 • 392 citations

Functional Multidrug Resistance Protein (MRP1) Lacking the N-terminal Transmembrane Domain

1998 • 318 citations

Interactions of the Human Multidrug Resistance Proteins MRP1 and MRP2 with Organic Anions

2000 • 313 citations

ATP-dependent 17β-Estradiol 17-(β-D-Glucuronide) Transport by Multidrug Resistance Protein (MRP)

1996 • 265 citations

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.

1996 • 262 citations

Membrane topology distinguishes a subfamily of the ATP‐binding cassette (ABC) transporters

1997 • 237 citations

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

2000 • 226 citations

Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein

1996 • 209 citations

MgADP Antagonism to Mg2+-independent ATP Binding of the Sulfonylurea Receptor SUR1

1997 • 169 citations

Mechanisms of multidrug resistance in HL60 cells

1989 • 140 citations

Anti‐cancer drugs and glutathione stimulate vanadate‐induced trapping of nucleotide in multidrug resistance‐associated protein (MRP)

1997 • 118 citations

ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells

1999 • 94 citations

Drug-stimulated Nucleotide Trapping in the Human Multidrug Transporter MDR1

1998 • 85 citations

Drug-stimulated ATPase activity of the human P-glycoprotein

1995 • 80 citations

Multidrug Resistance Protein

1998 • 80 citations

Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP)

1998 • 74 citations

Stimulation of ATPase Activity of Purified Multidrug Resistance-associated Protein by Nucleoside Diphosphates

1998 • 32 citations

Deleted Work

1955 • 0 citations

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