Structural Determinants of Integrin Recognition by Talin

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Integrins: A family of cell surface receptors

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Cation-π interactions in structural biology

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Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

2002 • 1,571 citations

Crystal Structure of the Extracellular Segment of Integrin αVβ3

2001 • 1,256 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling

2002 • 1,134 citations

Structural Basis of Collagen Recognition by Integrin α2β1

2000 • 945 citations

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

1993 • 891 citations

The Talin Head Domain Binds to Integrin β Subunit Cytoplasmic Tails and Regulates Integrin Activation

1999 • 697 citations

Structure of the ERM Protein Moesin Reveals the FERM Domain Fold Masked by an Extended Actin Binding Tail Domain

2000 • 594 citations

Breaking the Integrin Hinge

1996 • 567 citations

A Structural Mechanism of Integrin αIIbβ3 “Inside-Out” Activation as Regulated by Its Cytoplasmic Face

2002 • 511 citations

The Phosphotyrosine Interaction Domains of X11 and FE65 Bind to Distinct Sites on the YENPTY Motif of Amyloid Precursor Protein

1996 • 480 citations

Integrins and Actin Filaments: Reciprocal Regulation of Cell Adhesion and Signaling

2000 • 476 citations

Controlling basal expression in an inducible T7 expression system by blocking the target T7 promoter with lac repressor

1991 • 451 citations

The Phosphotyrosine Binding-like Domain of Talin Activates Integrins

2002 • 400 citations

Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain

2000 • 380 citations

ERM-Merlin and EBP50 Protein Families in Plasma Membrane Organization and Function

2000 • 375 citations

Conformation, Localization, and Integrin Binding of Talin Depend on Its Interaction with Phosphoinositides

2001 • 316 citations

Sequence and domain structure of talin

1990 • 314 citations

Identification of amino acid sequences in the integrin beta 1 cytoplasmic domain implicated in cytoskeletal association

1992 • 285 citations

Integrin β Cytoplasmic Domains Differentially Bind to Cytoskeletal Proteins

1998 • 282 citations

Colocalization of calcium-dependent protease II and one of its substrates at sites of cell adhesion

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Crystal Structure of the DNA Binding Domain of the Heat Shock Transcription Factor

1994 • 269 citations

Integrins isolated from Rous sarcoma virus-transformed chicken embryo fibroblasts.

1989 • 256 citations

Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site

1996 • 250 citations

Calpain Cleavage Promotes Talin Binding to the β3Integrin Cytoplasmic Domain

2001 • 219 citations

Disruption of thetalin gene arrests mouse development at the gastrulation stage

2000 • 208 citations

Crystal Structure of the Vinculin Tail Suggests a Pathway for Activation

1999 • 190 citations

Disruption of the Talin Gene Compromises Focal Adhesion Assembly in Undifferentiated but Not Differentiated Embryonic Stem Cells

1998 • 182 citations

Layilin, A Novel Talin-binding Transmembrane Protein Homologous with C-type Lectins, is Localized in Membrane Ruffles

1998 • 152 citations

NMR Analysis of Structure and Dynamics of the Cytosolic Tails of Integrin αIIbβ3 in Aqueous Solution

2001 • 117 citations

Identification of a Talin-binding Site in the Integrin β3 Subunit Distinct from the NPLY Regulatory Motif of Post-ligand Binding Functions

1999 • 81 citations

The generation of phase-sensitive 2D 15N1H spectra using gradient pulses for coherence-transfer-pathway selection

1992 • 67 citations

Effects of Mutations in the Cytoplasmic Domain of Integrin β1 to Talin Binding and Cell Spreading

1999 • 42 citations

Identification of Residues within the SHC Phosphotyrosine Binding/Phosphotyrosine Interaction Domain Crucial for Phosphopeptide Interaction

1996 • 36 citations