Crystal Structure of the Extracellular Segment of Integrin αVβ3 in Complex with an Arg-Gly-Asp Ligand

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1998 • 15,791 citations

Ligand Binding to Integrins

2000 • 1,332 citations

Crystal Structure of the Extracellular Segment of Integrin αVβ3

2001 • 1,256 citations

Structural Basis of Collagen Recognition by Integrin α2β1

2000 • 945 citations

Crystal structure of the A domain from the a subunit of integrin CR3 (CD11 b/CD18)

1995 • 893 citations

N-Methylated Cyclic RGD Peptides as Highly Active and Selective α_Vβ₃Integrin Antagonists

1999 • 803 citations

Ribbon models of macromolecules

1987 • 519 citations

Two conformations of the integrin A-domain (I-domain): a pathway for activation?

1995 • 400 citations

A novel divalent cation-binding site in the a domain of the ?2 integrin CR3 (CD11b/CD18) is essential for ligand binding

1993 • 383 citations

Integrin Structure

2000 • 371 citations

Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.

1995 • 308 citations

Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies

1993 • 206 citations

Three-dimensional structure of echistatin, the smallest active RGD protein

1991 • 199 citations

Locking in alternate conformations of the integrin αLβ2 I domain with disulfide bonds reveals functional relationships among integrin domains

2001 • 184 citations

Identification of a novel anti‐integrin monoclonal antibody that recognises a ligand‐induced binding site epitope on the β1 subunit

1995 • 151 citations

An Isoleucine-based Allosteric Switch Controls Affinity and Shape Shifting in Integrin CD11b A-domain

2000 • 142 citations

Two Functional States of the CD11b A-Domain: Correlations with Key Features of Two Mn2+-complexed Crystal Structures

1998 • 127 citations

A highly conserved sequence of the Arg-Gly-Asp-binding domain of the integrin beta 3 subunit is sensitive to stimulation

1991 • 60 citations

Echistatin: the refined structure of a disintegrin in solution by ¹ H NMR and restrained molecular dynamics

1994 • 33 citations