A Family of Human RNA-binding Proteins Related to theDrosophila Bruno Translational Regulator
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Abstract
References (87)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
Molecular cloning: A laboratory manual
1990 • 85,659 citations
Antibodies, a laboratory manual
1989 • 12,929 citations
Methods in yeast genetics
1979 • 7,824 citations
The Genome Sequence of Drosophila melanogaster
2000 • 5,882 citations
Methods in Yeast Genetics: A Laboratory Course Manual
1990 • 1,922 citations
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 • 1,873 citations
Methods in Yeast Genetics — A Laboratory Course Manual
1991 • 1,257 citations
Disruption of Splicing Regulated by a CUG-Binding Protein in Myotonic Dystrophy
1998 • 800 citations
RNA recognition: towards identifying determinants of specificity
1991 • 739 citations
RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein
1998 • 738 citations
Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors
1993 • 663 citations
Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein
1996 • 652 citations
Induction of germ cell formation by oskar
1992 • 643 citations
Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues.
1995 • 576 citations
FCA, a Gene Controlling Flowering Time in Arabidopsis, Encodes a Protein Containing RNA-Binding Domains
1997 • 544 citations
A nuclear localization domain in the hnRNP A1 protein.
1995 • 510 citations
A three-hybrid system to detect RNA-protein interactions in vivo.
1996 • 499 citations
Recognition of Polyadenylate RNA by the Poly(A)-Binding Protein
1999 • 494 citations
RNA binding specificity of hnRNP A1: significance of hnRNP A1 high-affinity binding sites in pre-mRNA splicing.
1994 • 481 citations
HNS, a nuclear-cytoplasmic shuttling sequence in HuR
1998 • 465 citations
Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in drosophila
1986 • 463 citations
Translational regulation of oskar mRNA by Bruno, an ovarian RNA-binding protein, is essential
1995 • 451 citations
Identification of a (CUG)n Triplet Repeat RNA-Binding Protein and Its Expression in Myotonic Dystrophy
1996 • 444 citations
Expansion of a CUG trinucleotide repeat in the 3′ untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts
1997 • 443 citations
Themes in RNA-protein recognition
1999 • 379 citations
The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins
1996 • 330 citations
Recruitment of Nanos to hunchback mRNA by Pumilio
1999 • 328 citations
Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA
1999 • 315 citations
A conserved family of elav-like genes in vertebrates.
1995 • 309 citations
RNA-binding proteins as regulators of gene expression
1997 • 263 citations
Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems
1999 • 251 citations
Sequential expression and role of Hu RNA-binding proteins during neurogenesis
1997 • 240 citations
Embryonic Lethal Abnormal Visual RNA-Binding Proteins Involved in Growth, Differentiation, and Posttranscriptional Gene Expression
1997 • 233 citations
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation
1998 • 227 citations
Dorsal-ventral patterning and differentiation of noggin-induced neural tissue in the absence of mesoderm
1995 • 215 citations
Translational repressorbruno plays multiple roles in development and is widely conserved
1997 • 213 citations
The RNP domain: a sequence-specific RNA-binding domain involved in processing and transport of RNA
1995 • 211 citations
ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells
1999 • 203 citations
Ectopic Expression of Hel-N1, an RNA-Binding Protein, Increases Glucose Transporter (GLUT1) Expression in 3T3-L1 Adipocytes
1997 • 200 citations
Transposon-facilitated DNA sequencing.
1991 • 199 citations
The complex pathology of trinucleotide repeats
1997 • 191 citations
Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein.
1988 • 180 citations
hnRNP A1 Selectively Interacts Through its Gly-rich Domain with Different RNA-binding Proteins
1996 • 179 citations
EDEN and EDEN-BP, a cis element and an associated factor that mediate sequence-specific mRNA deadenylation in Xenopus embryos
1998 • 175 citations
Multiple RRMs Contribute to RNA Binding Specificity and Affinity for Polypyrimidine Tract Binding Protein
1997 • 168 citations
Gene expression in the embryonic nervous system of Xenopus laevis.
1988 • 166 citations
Gene elav of Drosophila melanogaster: A prototype for neuronal‐specific RNA binding protein gene family that is conserved in flies and humans
1993 • 166 citations
ELAV, a Drosophila neuron-specific protein, mediates the generation of an alternatively spliced neural protein isoform
1996 • 163 citations
Purification and Properties of HuD, a Neuronal RNA-binding Protein
1996 • 163 citations
Specific isoforms of Squid, a Drosophila hnRNP, perform distinct roles in Gurken localization during oogenesis
1999 • 159 citations
Altered phosphorylation and intracellular distribution of a (CUG) n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice
1997 • 155 citations
Multiple RNA binding domains (RBDs) just don't add up
1995 • 139 citations
Renaturation of complementary DNA strands mediated by purified mammalian heterogeneous nuclear ribonucleoprotein A1 protein: implications for a mechanism for rapid molecular assembly.
1990 • 139 citations
Messenger ribonucleoprotein complexes containing human ELAV proteins: interactions with cytoskeleton and translational apparatus
1998 • 136 citations
Cis and trans effects of the myotonic dystrophy (DM) mutation in a cell culture model
1999 • 135 citations
Transcriptional abnormality in myotonic dystrophy affects DMPK but not neighboring genes
1997 • 135 citations
Effect of Myotonic Dystrophy Trinucleotide Repeat Expansion on DMPK Transcription and Processing
1995 • 133 citations
Absence of Myotonic Dystrophy Protein Kinase (DMPK) mRNA as a Result of a Triplet Repeat Expansion in Myotonic Dystrophy
1993 • 126 citations
Cytoplasmic localization is required for the mammalian ELAV‐like protein HuD to induce neuronal differentiation
1999 • 117 citations
Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophy
1999 • 117 citations
cDNAs with long CAG trinucleotide repeats from human brain
1997 • 103 citations
NOMENCLATURE
1997 • 103 citations
Two Different RNA Binding Activities for the AU-Rich Element and the Poly(A) Sequence of the Mouse Neuronal Protein mHuC
1996 • 100 citations
Two RNA-binding Domains Determine the RNA-binding Specificity of Nucleolin
1997 • 97 citations
The mec-8 gene of C. elegans encodes a protein with two RNA recognition motifs and regulates alternative splicing of unc-52 transcripts
1996 • 87 citations
TIA-1: Structural and Functional Studies on a New Class of Cytolytic Effector Molecule
1995 • 81 citations
New insights into the auxiliary domains of eukaryotic RNA binding proteins
1994 • 78 citations
The role ofelav-like genes, a conserved family encoding RNA-binding proteins, in growth and development
1997 • 70 citations
Multiple Sequence Elements and a Maternal mRNA Product Control cdk2 RNA Polyadenylation and Translation during Early Xenopus Development
1994 • 68 citations
Vegetal localization of the maternal mRNA encoding an EDEN-BP/Bruno-like protein in zebrafish
2000 • 68 citations
Translational regulation of oskar mRNA occurs independent of the cap and poly(A) tail in Drosophila ovarian extracts
1999 • 66 citations
Requirement of RBP9, a Drosophila Hu Homolog, for Regulation of Cystocyte Differentiation and Oocyte Determination during Oogenesis
1999 • 58 citations
Apontic binds the translational repressor Bruno and is implicated in regulation of oskar mRNA translation
1999 • 57 citations
HnRNP proteins and the nuclear export of mRNA
1997 • 47 citations
Developmentally-regulated expression of mNapor encoding an apoptosis-induced ELAV-type RNA binding protein
1999 • 44 citations
Embryo Deadenylation Element-Dependent Deadenylation Is Enhanced by a cis Element Containing AUU Repeats
1998 • 42 citations
ETR-1, a homologue of a protein linked to myotonic dystrophy, is essential for muscle development in Caenorhabditis elegans
1999 • 42 citations
Three new members of the RNP protein family inXenopus
1993 • 42 citations
Sex-lethal Interactions with Protein and RNA
1997 • 41 citations
Activities of the Sex-lethal protein in RNA binding and protein:protein interactions
1998 • 41 citations
Fluorescent differential display analysis of gene expression in apoptotic neuroblastoma cells
1998 • 39 citations
[5] Yeast three-hybrid system to detect and analyze interactions between RNA and protein
1999 • 38 citations
Myotonic dystrophy: discussion of molecular mechanism.
1996 • 37 citations
Protein-RNA and Protein-Protein Interactions of the Drosophila Sex-Lethal Mediated by Its RNA-Binding Domains
1996 • 32 citations
(CTG)n repeats markedly inhibit differentiation of the C2C12 myoblast cell line: implications for congenital myotonic dystrophy
1999 • 20 citations
Misexpression of the RNA-binding protein ELRB in Xenopus presumptive neurectoderm induces proliferation arrest and programmed cell death.
1999 • 8 citations