RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

AU-rich elements: characterization and importance in mRNA degradation

1995 • 1,936 citations

mRNA stability in mammalian cells

1995 • 1,258 citations

Nucleocytoplasmic transport: signals, mechanisms and regulation

1997 • 987 citations

Regulation of Lymphokine Messenger RNA Stability by a Surface-Mediated T Cell Activation Pathway

1989 • 910 citations

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the invivo stability of ARE-containing mRNAs

1998 • 852 citations

INTERRELATIONSHIPS OF THE PATHWAYS OF mRNA DECAY AND TRANSLATION IN EUKARYOTIC CELLS

1996 • 653 citations

Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein

1996 • 652 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

Purification, characterization, and cDNA cloning of an AU-rich element RNA-binding protein, AUF1.

1993 • 533 citations

When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells.

1995 • 515 citations

A Hierarchy of Hu RNA Binding Proteins in Developing and Adult Neurons

1997 • 367 citations

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.

1993 • 356 citations

Modulation of the Fate of Cytoplasmic mRNA by AU-Rich Elements: Key Sequence Features Controlling mRNA Deadenylation and Decay

1997 • 352 citations

Glyceraldehyde-3-phosphate Dehydrogenase Selectively Binds AU-rich RNA in the NAD+-binding Region (Rossmann Fold)

1995 • 345 citations

Life and death in the cytoplasm: messages from the 3′ end

1997 • 335 citations

A conserved family of elav-like genes in vertebrates.

1995 • 309 citations

Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay

1997 • 302 citations

mRNA Decay Mediated by Two Distinct AU-Rich Elements from c-fos and Granulocyte-Macrophage Colony-Stimulating Factor Transcripts: Different Deadenylation Kinetics and Uncoupling from Translation

1995 • 276 citations

Selective Degradation of Early-Response-Gene mRNAs: Functional Analyses of Sequence Features of the AU-Rich Elements

1994 • 253 citations

Sequential expression and role of Hu RNA-binding proteins during neurogenesis

1997 • 240 citations

Embryonic Lethal Abnormal Visual RNA-Binding Proteins Involved in Growth, Differentiation, and Posttranscriptional Gene Expression

1997 • 233 citations

Nuclear export of proteins and RNAs

1997 • 209 citations

Association of heterogeneous nuclear ribonucleoprotein A1 and C proteins with reiterated AUUUA sequences.

1993 • 208 citations

The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA

1997 • 206 citations

Ectopic Expression of Hel-N1, an RNA-Binding Protein, Increases Glucose Transporter (GLUT1) Expression in 3T3-L1 Adipocytes

1997 • 200 citations

Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function

1994 • 184 citations

Transcription-Dependent and Transcription-Independent Nuclear Transport of hnRNP Proteins

1991 • 184 citations

Purification, Characterization, and cDNA Cloning of an AU-Rich Element RNA-Binding Protein, AUF1

1993 • 177 citations

Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements.

1994 • 165 citations

Purification and Properties of HuD, a Neuronal RNA-binding Protein

1996 • 163 citations

Functional Characterization of a Non-AUUUA AU-Rich Element from the c-jun Proto-Oncogene mRNA: Evidence for a Novel Class of AU-Rich Elements

1996 • 154 citations

Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.

1994 • 153 citations

A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy

1998 • 148 citations

The Elav-like Proteins Bind to a Conserved Regulatory Element in the 3′-Untranslated Region of GAP-43 mRNA

1997 • 142 citations

U-rich sequence-binding proteins (URBPs) interacting with a 20-nucleotide U-rich sequence in the 3' untranslated region of c-fos mRNA may be involved in the first step of c-fos mRNA degradation.

1992 • 135 citations

AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity.

1995 • 126 citations

Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation

1996 • 122 citations

Cyclosporin A inhibits growth of autocrine tumour cell lines by destabilizing interleukin-3 mRNA

1994 • 110 citations

Hel-N1: an Autoimmune RNA-Binding Protein with Specificity for 3' Uridylate-Rich Untranslated Regions of Growth Factor mRNAs

1993 • 108 citations

Two Different RNA Binding Activities for the AU-Rich Element and the Poly(A) Sequence of the Mouse Neuronal Protein mHuC

1996 • 100 citations

Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function.

1994 • 86 citations

Developmental expression of AUF1 and HuR, two c-myc mRNA binding proteins

1998 • 72 citations

From Transcript to Protein

1996 • 71 citations

A novel strategy for the immunological tagging of cdna constructs

1993 • 53 citations

Interrelationships of the Pathways of mRNA Decay and Translation in Eukaryotic Cells

1996 • 50 citations

Purification of an AU-Rich RNA Binding Protein from Sarcophaga peregrina (Flesh Fly) and Its Identification as a Thiolase1

1993 • 39 citations

U-Rich Sequence-Binding Proteins (URBPs) Interacting with a 20-Nucleotide U-Rich Sequence in the 3′ Untranslated Region of c-fos mRNA May Be Involved in the First Step of c-fos mRNA Degradation

1992 • 35 citations

Short- and long-term mechanisms of tau regulation in PC12 cells

1995 • 26 citations