ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

AU-rich elements: characterization and importance in mRNA degradation

1995 • 1,936 citations

Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.

1986 • 1,591 citations

SRα Promoter: an Efficient and Versatile Mammalian cDNA Expression System Composed of the Simian Virus 40 Early Promoter and the R-U5 Segment of Human T-Cell Leukemia Virus Type 1 Long Terminal Repeat

1988 • 1,351 citations

Improved Green Fluorescent Protein by Molecular Evolution Using DNA Shuffling

1996 • 1,212 citations

TRANSLATIONAL CONTROL IN MAMMALIAN CELLS

1991 • 1,041 citations

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the invivo stability of ARE-containing mRNAs

1998 • 852 citations

Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

1984 • 808 citations

A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.

1987 • 767 citations

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

1998 • 738 citations

Hypoxic Stabilization of Vascular Endothelial Growth Factor mRNA by the RNA-binding Protein HuR

1998 • 662 citations

INTERRELATIONSHIPS OF THE PATHWAYS OF mRNA DECAY AND TRANSLATION IN EUKARYOTIC CELLS

1996 • 653 citations

Cloning and Characterization of HuR, a Ubiquitously Expressed Elav-like Protein

1996 • 652 citations

SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat.

1988 • 638 citations

Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons

1992 • 612 citations

HNS, a nuclear-cytoplasmic shuttling sequence in HuR

1998 • 465 citations

NTera 2 Cells: A human cell line which displays characteristics expected of a human committed neuronal progenitor cell

1993 • 435 citations

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

1996 • 394 citations

Neurofilaments are obligate heteropolymers in vivo

1993 • 387 citations

A Hierarchy of Hu RNA Binding Proteins in Developing and Adult Neurons

1997 • 367 citations

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs.

1993 • 356 citations

Modulation of the Fate of Cytoplasmic mRNA by AU-Rich Elements: Key Sequence Features Controlling mRNA Deadenylation and Decay

1997 • 352 citations

The locus elav of Drosophila melanogaster is expressed in neurons at all developmental stages

1988 • 351 citations

Life and death in the cytoplasm: messages from the 3′ end

1997 • 335 citations

A conserved family of elav-like genes in vertebrates.

1995 • 309 citations

Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay

1997 • 302 citations

Why is Hu where? Shuttling of early-response-gene messenger RNA subsets

1999 • 294 citations

The human mid-size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family.

1987 • 278 citations

mRNA Decay Mediated by Two Distinct AU-Rich Elements from c-fos and Granulocyte-Macrophage Colony-Stimulating Factor Transcripts: Different Deadenylation Kinetics and Uncoupling from Translation

1995 • 276 citations

Onconeural antigens and the paraneoplastic neurologic disorders: at the intersection of cancer, immunity, and the brain.

1996 • 273 citations

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments

1993 • 270 citations

ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system

1999 • 244 citations

Sequential expression and role of Hu RNA-binding proteins during neurogenesis

1997 • 240 citations

Embryonic Lethal Abnormal Visual RNA-Binding Proteins Involved in Growth, Differentiation, and Posttranscriptional Gene Expression

1997 • 233 citations

ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation

1998 • 227 citations

Mutant Alleles at the Locus elav in Drosophila melanogaster lead to Nervous System Defects. A Developmental-Genetic Analysis

1985 • 203 citations

Ectopic Expression of Hel-N1, an RNA-Binding Protein, Increases Glucose Transporter (GLUT1) Expression in 3T3-L1 Adipocytes

1997 • 200 citations

Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex.

1992 • 181 citations

Mammalian homologs of Drosophila ELAV localized to a neuronal subset can bind in vitro to the 3' UTR of mRNA encoding the Id transcriptional repressor

1994 • 168 citations

Purification and Properties of HuD, a Neuronal RNA-binding Protein

1996 • 163 citations

Functional Characterization of a Non-AUUUA AU-Rich Element from the c-jun Proto-Oncogene mRNA: Evidence for a Novel Class of AU-Rich Elements

1996 • 154 citations

Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1.

1994 • 153 citations

The Elav-like Proteins Bind to a Conserved Regulatory Element in the 3′-Untranslated Region of GAP-43 mRNA

1997 • 142 citations

Messenger ribonucleoprotein complexes containing human ELAV proteins: interactions with cytoskeleton and translational apparatus

1998 • 136 citations

Hel-N1/Hel-N2 proteins are bound to poly(A)+ mRNA in granular RNP structures and are implicated in neuronal differentiation

1996 • 122 citations

Paraneoplastic Encephalomyelitis Antigens Bind to the AU-rich Elements of mRNA

1995 • 120 citations

Expression of NF-L and NF-M in fibroblasts reveals coassembly of neurofilament and vimentin subunits.

1989 • 114 citations

Hel-N1: an Autoimmune RNA-Binding Protein with Specificity for 3' Uridylate-Rich Untranslated Regions of Growth Factor mRNAs

1993 • 108 citations

Expression of rat neurofilament proteins NF-L and NF-M in transfected non-neuronal cells.

1989 • 89 citations

Transfected rat high-molecular-weight neurofilament (NF-H) coassembles with vimentin in a predominantly nonphosphorylated form

1990 • 88 citations

In vitro selection of an RNA epitope immunologically cross-reactive with a peptide.

1992 • 74 citations

From Transcript to Protein

1996 • 71 citations

Phosphorylation of neurofilament proteins in intact neurons: demonstration of phosphorylation in cell bodies and axons

1988 • 70 citations

Interrelationships of the Pathways of mRNA Decay and Translation in Eukaryotic Cells

1996 • 50 citations

Target specificity of neuronal RNA-binding protein, Mel-N1: direct binding to the 3' untranslated region of its own mRNA

1996 • 48 citations

Translational Control In Mammalian Cells

1991 • 47 citations

Actinomycin prevents the destabilization of neurofilament mRNA in primary sensory neurons.

1992 • 44 citations

Characterization of Interactions between the Neurofilament Triplet Proteins by the Yeast Two-hybrid System

1996 • 43 citations

Regulation of glucose transport as well as glucose transporter and immediate early gene expression in 3T3‐L1 preadipocytes by 8‐bromo‐cAMP

1991 • 42 citations

Binding of a 40-kDa Protein to the N-myc 3ʹ-Untranslated Region Correlates with Enhanced N-myc Expression in Human Neuroblastoma

1996 • 37 citations

Hel-N2: a novel isoform of Hel-N1 which is conserved in rat neural tissue and produced in early embryogenesis

1994 • 28 citations