Disruption of Splicing Regulated by a CUG-Binding Protein in Myotonic Dystrophy

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

α-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere

1994 • 1,008 citations

Identification of a (CUG)n Triplet Repeat RNA-Binding Protein and Its Expression in Myotonic Dystrophy

1996 • 444 citations

Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle.

1991 • 372 citations

The roles of heterogeneous nuclear ribonucleoproteins (hnRNP) in RNA metabolism

1996 • 205 citations

Relationship Between Parental Trinucleotide GCT Repeat Length and Severity of Myotonic Dystrophy in Offspring

1993 • 193 citations

The expression cassette determines the functional activity of ribozymes in mammalian cells by controlling their intracellular localization.

1997 • 192 citations

Novel Proteins with Binding Specificity for DNA CTG Repeats And RNA Cug Repeats: Implications for Myotonic Dystrophy

1996 • 192 citations

Myotonic dystrophy: evidence for a possible dominant-negative RNA mutation

1995 • 172 citations

Altered phosphorylation and intracellular distribution of a (CUG) _n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout mice

1997 • 155 citations

Transcriptional abnormality in myotonic dystrophy affects DMPK but not neighboring genes

1997 • 135 citations

Effect of Myotonic Dystrophy Trinucleotide Repeat Expansion on DMPK Transcription and Processing

1995 • 133 citations

Clones of Human Satellite Cells Can Express in Vitro both Fast and Slow Myosin Heavy Chains

1994 • 120 citations

A Single Troponin T Gene Regulated by Different Programs in Cardiac and Skeletal Muscle Development

1984 • 113 citations

Muscle-Specific Splicing Enhancers Regulate Inclusion of the Cardiac Troponin T Alternative Exon in Embryonic Skeletal Muscle

1996 • 98 citations

Cardiac involvement in a large kindred with myotonic dystrophy. Quantitative assessment and relation to size of CTG repeat expansion.

1995 • 67 citations

Myotonic dystrophy: Molecular windows on a complex etiology

1998 • 54 citations

In vitro splicing of cardiac troponin T precursors. Exon mutations disrupt splicing of the upstream intron.

1992 • 51 citations

Cardiac Involvement in a Large Kindred With Myotonic Dystrophy

1995 • 47 citations

Myotonic dystrophy: discussion of molecular mechanism.

1996 • 37 citations