Dissimilar phorbol ester binding properties of the individual cysteine‐rich motifs of protein kinase D

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

Protein Kinase C: Structure, Function, and Regulation

1995 • 1,640 citations

Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol ester

1995 • 643 citations

PKCu is a novel, atypical member of the protein kinase C family.

1994 • 519 citations

Phorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequence.

1989 • 439 citations

Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain.

1994 • 406 citations

Regulation of Phosphoinositide Phospholipases by Hormones, Neurotransmitters, and Other Agonists Linked to G Proteins

1996 • 362 citations

Taxonomy and function of C1 protein kinase C homology domains

1997 • 350 citations

Protein kinase D (PKD) activation in intact cells through a protein kinase C-dependent signal transduction pathway.

1996 • 244 citations

Protein kinase C contains two phorbol ester binding domains.

1991 • 234 citations

Identification and Characterization of Zinc Binding Sites in Protein Kinase C

1991 • 193 citations

Expression and Characterization of PKD, a Phorbol Ester and Diacylglycerol-stimulated Serine Protein Kinase

1995 • 170 citations

Homologous and heterologous mitogenic desensitization of Swiss 3T3 cells to phorbol esters and vasopressin: Role of receptor and postreceptor steps

1984 • 154 citations

Residues in the Second Cysteine-rich Region of Protein Kinase C δ Relevant to Phorbol Ester Binding as Revealed by Site-directed Mutagenesis

1995 • 149 citations

Protein Kinase D Activation by Mutations within Its Pleckstrin Homology Domain

1998 • 142 citations

Two novel protein kinase C-related genes of fission yeast are essential for cell viability and implicated in cell shape control.

1993 • 139 citations

Identification, Cloning, and Sequence of a Major Allergen (Hev b 5) from Natural Rubber Latex (Hevea brasiliensis)

1996 • 137 citations

Non-equivalent Roles for the First and Second Zinc Fingers of Protein Kinase Cδ

1996 • 133 citations

The protein kinase C and protein kinase C related gene families

1995 • 119 citations

Protein Kinase Cα Contains Two Activator Binding Sites That Bind Phorbol Esters and Diacylglycerols with Opposite Affinities

1996 • 114 citations

A phorbol ester binding domain of protein kinase C gamma. Deletion analysis of the Cys2 domain defines a minimal 43-amino acid peptide.

1994 • 105 citations

The regulatory region of protein kinase C gamma. Studies of phorbol ester binding to individual and combined functional segments expressed as glutathione S-transferase fusion proteins indicate a complex mechanism of regulation by phospholipids, phorbol esters, and divalent cations.

1994 • 84 citations

Bryostatin 1 Induces Biphasic Activation of Protein Kinase D in Intact Cells

1997 • 74 citations

In vitro activation and substrates of recombinant, baculovirus expressed human protein kinase Cμ

1996 • 72 citations

Protein kinase D: a novel target for diacylglycerol and phorbol esters

1997 • 68 citations

Protein kinase D (PKD): A novel target for diacylglycerol and phorbol esters

1995 • 57 citations

Differential protein kinase C ligand regulation detected in vivo by a phenotypic yeast assay

1995 • 33 citations