In vitro activation and substrates of recombinant, baculovirus expressed human protein kinase Cμ

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Protein kinase C isoenzymes: divergence in signal transduction?

1993 • 1,237 citations

Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.

1993 • 966 citations

Protein kinase C - a question of specificity

1994 • 958 citations

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

1994 • 749 citations

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin

1992 • 728 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol ester

1995 • 643 citations

Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3.

1994 • 553 citations

PKCu is a novel, atypical member of the protein kinase C family.

1994 • 519 citations

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid.

1995 • 506 citations

The Marcks brothers: A family of protein kinase C substrates

1992 • 474 citations

The protein kinase C family

1992 • 399 citations

Lipid second messengers

1994 • 357 citations

PH domain: the first anniversary

1994 • 318 citations

The influence of basic residues on the substrate specificity of protein kinase C.

1987 • 287 citations

Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes.

1993 • 275 citations

A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells.

1994 • 236 citations

Calcium · calmodulin-dependent protein kinase II and calcium · phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide

1987 • 173 citations

Expression and Characterization of PKD, a Phorbol Ester and Diacylglycerol-stimulated Serine Protein Kinase

1995 • 170 citations

Calcium-Independent Activation of Hypothalamic Type I Protein Kinase C by Unsaturated Fatty Acids

1988 • 120 citations

Expression and properties of two distinct classes of the phorbol ester receptor family, four conventional protein kinase C types, and a novel protein kinase C.

1990 • 104 citations

Characterization of Activators and Inhibitors of Protein Kinase Cμ

1995 • 89 citations

The Myristoylated Alanine‐Rich C‐Kinase Substrate (MARCKS) is Sequentially Phosphorylated by Conventional, Novel and Atypical Isotypes of Protein Kinase C

1995 • 89 citations

Potentiation of diacylglycerol‐induced activation of protein kinase C by lysophospholipids

1993 • 88 citations

A method for measuring protein kinase C activity in permeabilized T lymphocytes by using peptide substrates. Evidence for multiple pathways of kinase activation

1990 • 81 citations

Protein kinase C activation potently down-regulates the expression of its major substrate, 80K, in Swiss 3T3 cells.

1991 • 62 citations

[55] Expression of protein kinase c isotypes using baculovirus vectors

1991 • 43 citations

Interaction of protein kinase C with phosphoinositides

1991 • 28 citations

DNA strand separation, renaturation and hybridization

1994 • 9 citations