Visualization of Myc/Max/Mad Family Dimers and the Competition for Dimerization in Living Cells

Missing Pieces in the NF-κB Puzzle

2002 • 3,560 citations

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

1997 • 2,062 citations

Visualization of Interactions among bZIP and Rel Family Proteins in Living Cells Using Bimolecular Fluorescence Complementation

2002 • 1,516 citations

The Myc/Max/Mad Network and the Transcriptional Control of Cell Behavior

2000 • 1,307 citations

Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

1997 • 945 citations

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

1993 • 786 citations

Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

2003 • 767 citations

Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A

1997 • 739 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity

1993 • 711 citations

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

1997 • 654 citations

Oncogenic activity of the c-Myc protein requires dimerization with Max

1993 • 543 citations

Correlation of Two-Hybrid Affinity Data with In Vitro Measurements

1995 • 536 citations

X-Ray Structures of Myc-Max and Mad-Max Recognizing DNA

2003 • 506 citations

The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc

2000 • 479 citations

An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3

1995 • 372 citations

Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter

2001 • 334 citations

Switch from Myc/Max to Mad1/Max binding and decrease in histone acetylation at the telomerase reverse transcriptase promoter during differentiation of HL60 cells

2001 • 319 citations

Small-molecule antagonists of Myc/Max dimerization inhibit Myc-induced transformation of chicken embryo fibroblasts

2002 • 314 citations

A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation.

1993 • 294 citations

Max: functional domains and interaction with c-Myc.

1992 • 280 citations

Function and regulation of the transcription factors of the Myc/Max/Mad network

2001 • 244 citations

Regulation of tumor suppressors by nuclear-cytoplasmic shuttling

2003 • 231 citations

The basic region/helix – loop – helix/leucine zipper domain of Myc proto-oncoproteins: Function and regulation

1999 • 206 citations

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

1989 • 198 citations

Design and properties of a Myc derivative that efficiently homodimerizes

1998 • 182 citations

The crystal structure of an intact human Max–DNA complex: new insights into mechanisms of transcriptional control

1997 • 162 citations

Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc.

1994 • 159 citations

Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis.

1995 • 146 citations

Gene-target recognition among members of the Myc superfamily and implications for oncogenesis

2000 • 138 citations

MondoA, a Novel Basic Helix-Loop-Helix–Leucine Zipper Transcriptional Activator That Constitutes a Positive Branch of a Max-Like Network

2000 • 129 citations

Sequential expression of the MAD family of transcriptional repressors during differentiation and development

1998 • 129 citations

Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1.

1994 • 125 citations

Identification and Characterization of Specific DNA-binding Complexes Containing Members of the Myc/Max/Mad Network of Transcriptional Regulators

1998 • 116 citations

An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity

2003 • 110 citations

DNA specificity enhanced by sequential binding of protein monomers

1999 • 102 citations

Cell growth inhibition by the Mad/Max complex through recruitment of histone deacetylase activity

1997 • 99 citations

MXI1, a putative tumor suppressor gene, suppresses growth of human glioblastoma cells.

1997 • 98 citations

A 13-Amino Acid Amphipathic α-Helix Is Required for the Functional Interaction between the Transcriptional Repressor Mad1 and mSin3A

1999 • 62 citations

Mutational analysis of Max: role of basic, helix-loop-helix/leucine zipper domains in DNA binding, dimerization and regulation of Myc-mediated transcriptional activation.

1992 • 53 citations

The leucine zippers of the HLH-LZ proteins Max and c-Myc preferentially form heterodimers

1995 • 51 citations

Both the helix-loop-helix and the leucine zipper motifs of c-Myc contribute to its dimerization specificity with Max.

1993 • 38 citations

Dynamic in vivo interactions among Myc network members

2001 • 34 citations

Analysis of the Myc and Max Interaction Specificity with λ Repressor-HLH Domain Fusions

1995 • 24 citations

Interfacial Asparagine Residues within an Amide Tetrad Contribute to Max Helix-Loop-Helix Leucine Zipper Homodimer Stability

2000 • 8 citations

NOVEL EXPRESSION PATTERNS OF THE MYC/MAX/MAD TRANSCRIPTION FACTOR NETWORK IN DEVELOPING MURINE PROSTATE GLAND

2001 • 6 citations