The crystal structure of an intact human Max–DNA complex: new insights into mechanisms of transcriptional control

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1993 • 3,564 citations

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

Improved Fourier coefficients for maps using phases from partial structures with errors

1986 • 1,897 citations

Max: A Helix-Loop-Helix Zipper Protein That Forms a Sequence-Specific DNA-Binding Complex with Myc

1991 • 1,650 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

myc FUNCTION AND REGULATION

1992 • 790 citations

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

1993 • 786 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity

1993 • 711 citations

Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1995 • 587 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

1992 • 458 citations

Crystal structure of MyoD bHLH domain-DNA complex: Perspectives on DNA recognition and implications for transcriptional activation

1994 • 448 citations

Crystal structure of transcription factor E47: E-box recognition by a basic region helix-loop-helix dimer.

1994 • 420 citations

Structure and function of the b/HLH/Z domain of USF.

1994 • 390 citations

Packing of α-helices: Geometrical constraints and contact areas

1978 • 366 citations

Myc—Max—Mad: a transcription factor network controlling cell cycle progression, differentiation and death

1994 • 365 citations

Structure of proteins: packing of alpha-helices and pleated sheets.

1977 • 333 citations

Max: functional domains and interaction with c-Myc.

1992 • 280 citations

An Essential E Box in the Promoter of the Gene Encoding the mRNA Cap-Binding Protein (Eukaryotic Initiation Factor 4E) Is a Target for Activation by c-myc

1996 • 232 citations

Casein kinase II inhibits the DNA-binding activity of Max homodimers but not Myc/Max heterodimers.

1992 • 230 citations

Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

1989 • 198 citations

TFEB has DNA-binding and oligomerization properties of a unique helix-loop-helix/leucine-zipper family.

1991 • 174 citations

Molecular Characterization of Helix-Loop-Helix Peptides

1992 • 166 citations

Mad Proteins Contain a Dominant Transcription Repression Domain

1996 • 163 citations

Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc.

1994 • 159 citations

Use of dynamic light scattering to assess crystallizability of macromolecules and macromolecular assemblies

1994 • 131 citations

Alternative Forms of Max as Enhancers or Suppressors of Myc-Ras Cotransformation

1992 • 130 citations

Base preferences for DNA binding by the bHLH-Zip protein USF: effects of MgCl₂on specificity and comparison with binding of Myc family members

1994 • 126 citations

Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc.

1996 • 113 citations

Multiple oligomeric states regulate the DNA binding of helix-loop-helix peptides.

1993 • 103 citations

Transcription activation by Myc and Max: flanking sequences target activation to a subset of CACGTG motifs in vivo.

1993 • 90 citations

Identification of casein kinase II phosphorylation sites in Max: effects on DNA-binding kinetics of Max homo- and Myc/Max heterodimers.

1993 • 80 citations

Myc/Max and other helix-loop-helix/leucine zipper proteins bend DNA toward the minor groove.

1992 • 79 citations

High affinity DNA-binding Myc analogs: Recognition by an α helix

1993 • 75 citations

Isolation of phosphorylated calmodulin from rat liver and identification of the in vivo phosphorylation sites.

1994 • 66 citations

c-Myc and Max transregulate the mouse ornithine decarboxylase promoter through interaction with two downstream CACGTG motifs.

1995 • 57 citations

Mutational analysis of Max: role of basic, helix-loop-helix/leucine zipper domains in DNA binding, dimerization and regulation of Myc-mediated transcriptional activation.

1992 • 53 citations

The leucine zippers of the HLH-LZ proteins Max and c-Myc preferentially form heterodimers

1995 • 51 citations

DEMON/ANGEL: a suite of programs to carry out density modification

1995 • 49 citations

The dimerization stability of the HLH-LZ transcription protein family is modulated by the leucine zippers: A CD and NMR study of TFEB and c-Myc

1994 • 43 citations

Do basic region-leucine zipper proteins bend their DNA targets ... does it matter?

1996 • 31 citations

Max activity is affected by phosphorylation at two NH2-terminal sites.

1994 • 28 citations

Anti-cooperative Biphasic Equilibrium Binding of Transcription Factor Upstream Stimulatory Factor to Its Cognate DNA Monitored by Protein Fluorescence Changes

1995 • 24 citations