Gene-target recognition among members of the Myc superfamily and implications for oncogenesis

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

1997 • 4,870 citations

Use of a cDNA microarray to analyse gene expression patterns in human cancer

1996 • 2,002 citations

c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism

1999 • 1,650 citations

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB

1997 • 1,162 citations

Sequence-Specific DNA Binding by the c-Myc Protein

1990 • 893 citations

Proteins of the Myc Network: Essential Regulators of Cell Growth and Differentiation

1996 • 787 citations

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain

1993 • 723 citations

Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity

1993 • 711 citations

Ratio-based decisions and the quantitative analysis of cDNA microarray images

1997 • 539 citations

Myc and Max proteins possess distinct transcriptional activities

1992 • 478 citations

Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements.

1992 • 449 citations

Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays.

1998 • 444 citations

Transient excess of MYC activity can elicit genomic instability and tumorigenesis

1999 • 409 citations

Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation

1999 • 404 citations

Structure and function of the b/HLH/Z domain of USF.

1994 • 390 citations

An amino-terminal domain of Mxi1 mediates anti-myc oncogenic activity and interacts with a homolog of the Yeast Transcriptional Repressor SIN3

1995 • 372 citations

The role of c-myc in cell growth

1993 • 365 citations

Myc—Max—Mad: a transcription factor network controlling cell cycle progression, differentiation and death

1994 • 365 citations

Coordinated Regulation of Iron-Controlling Genes, H-Ferritin and IRP2 , by c-MYC

1999 • 319 citations

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II.

1994 • 313 citations

Myc target genes

1997 • 289 citations

Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites.

1997 • 248 citations

Myc-Max heterodimers activate a DEAD box gene and interact with multiple E box-related sites in vivo.

1996 • 210 citations

Single amino acid substitutions alter helix-loop-helix protein specificity for bases flanking the core CANNTG motif.

1992 • 199 citations

Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition

1997 • 196 citations

Determination of the c-MYC DNA-binding site.

1991 • 181 citations

Myc represses the growth arrest gene gadd45

1997 • 149 citations

Myc and Max function as a nucleoprotein complex

1992 • 143 citations

Myc family oncoproteins function through a common pathway to transform normal cells in culture: cross-interference by Max and trans-acting dominant mutants.

1992 • 129 citations

Distinct DNA binding preferences for the c-Myc/Max and Max/Max dimers

1993 • 112 citations

Repression by the Mad(Mxi1)-Sin3 complex

1998 • 110 citations

Myc represses transcription of the growth arrest gene gas1

1997 • 88 citations

C-Myc Transrepression and Cell Transformation

1997 • 11 citations

Genomic Cloning and Characterization of the Human Eukaryotic Initiation Factor-2β Promoter

1999 • 8 citations