Notch signaling is an important regulator of type 2 immunity

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

2001 • 3,036 citations

The lineage decisions of helper T cells

2002 • 1,678 citations

Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1

1999 • 1,392 citations

Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination

1999 • 956 citations

Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells

2004 • 890 citations

MAML1, a human homologue of Drosophila Mastermind, is a transcriptional co-activator for NOTCH receptors

2000 • 576 citations

The nervous system and innate immunity: the neuropeptide connection

2005 • 436 citations

REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY

2005 • 434 citations

Notch Activity Influences the αβ versus γδ T Cell Lineage Decision

1997 • 399 citations

Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling

2003 • 380 citations

Inactivation of Notch1 Impairs VDJβ Rearrangement and Allows pre-TCR-Independent Survival of Early αβ Lineage Thymocytes

2002 • 342 citations

Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling

2004 • 306 citations

Mastermind critically regulates Notch-mediated lymphoid cell fate decisions

2004 • 289 citations

Delta1-Notch3 Interactions Bias the Functional Differentiation of Activated CD4+ T Cells

2003 • 289 citations

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21.

2005 • 275 citations

p300 and PCAF Act Cooperatively To Mediate Transcriptional Activation from Chromatin Templates by Notch Intracellular Domains In Vitro

2002 • 267 citations

Signaling pathways in Th2 development

2004 • 258 citations

Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation

2004 • 254 citations

The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity

2004 • 249 citations

TCR-Mediated Notch Signaling Regulates Proliferation and IFN-γ Production in Peripheral T Cells

2003 • 228 citations

Notch Signaling Augments T Cell Responsiveness by Enhancing CD25 Expression

2003 • 218 citations

CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

2002 • 216 citations

Structural Requirements for Assembly of the CSL·Intracellular Notch1·Mastermind-like 1 Transcriptional Activation Complex

2003 • 204 citations

Notch 1 Signaling Regulates Peripheral T Cell Activation

2004 • 159 citations

Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

2005 • 134 citations

Vaccination against cutaneous leishmaniasis in a murine model. II. Immunologic properties of protective and nonprotective subfractions of soluble promastigote extract.

1987 • 97 citations

Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell–dependent mechanism

2003 • 73 citations

Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell–dependent mechanism

2003 • 68 citations

Notch1 expression on T cells is not required for CD4⁺ T helper differentiation

2004 • 45 citations

Hepatogenic Potential of Stem Cells and Lymphoid Precursors.

2005 • 1 citations