Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor-β1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid

1961 • 3,860 citations

Matrix Metalloproteinases

1999 • 3,774 citations

Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy

2001 • 1,727 citations

Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung.

1997 • 1,010 citations

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

1994 • 743 citations

Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum

1992 • 705 citations

Matrix as a Modulator of Hepatic Fibrogenesis

2001 • 535 citations

Extracellular Matrix Degradation and the Role of Hepatic Stellate Cells

2001 • 486 citations

TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?

2000 • 412 citations

Sputum Metalloproteinase-9/Tissue Inhibitor of Metalloproteinase-1 Ratio Correlates with Airflow Obstruction in Asthma and Chronic Bronchitis

1998 • 396 citations

Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung

2001 • 261 citations

Connective tissue growth factor mRNA expression is upregulated in bleomycin-induced lung fibrosis

1998 • 242 citations

Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-β1 and TGF-β3

1999 • 228 citations

Characteristic Elevation of Matrix Metalloproteinase Activity in Idiopathic Interstitial Pneumonias

2000 • 217 citations

Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-beta precede bleomycin-induced pulmonary fibrosis in mice.

1988 • 199 citations

Differential Effects of Transforming Growth Factor-β on the Expression of Collagenase-1 and Collagenase-3 in Human Fibroblasts

1998 • 192 citations

Increased Risk of Fibrosing Alveolitis Associated with Interleukin-1 Receptor Antagonist and Tumor Necrosis Factor- α Gene Polymorphisms

2000 • 186 citations

Transient Transgene Expression of Decorin in the Lung Reduces the Fibrotic Response to Bleomycin

2001 • 184 citations

Analysis of Tumor Necrosis Factor- α , Lymphotoxin- α , Tumor Necrosis Factor Receptor II, and Interleukin-6 Polymorphisms in Patients with Idiopathic Pulmonary Fibrosis

2001 • 141 citations

Interstitial fibrosis and growth factors.

2000 • 129 citations

Immunohistochemical Localization of Transforming Growth Factor β and Tumor Necrosis Factor α in the Lungs of Fibrosis-Prone and "Non-Fibrosing" Mice during the Latent Period and Early Phase after Irradiation

1997 • 120 citations

The pathogenesis of pulmonary fibrosis: Is there a fibrosis gene?

1997 • 116 citations

Differences in Correlation of mRNA Gene Expression in Mice Sensitive and Resistant to Radiation-Induced Pulmonary Fibrosis

1995 • 103 citations

Matrix Metalloproteinases 2, 9, and 13, and Tissue Inhibitors of Metalloproteinases 1 and 2 in Experimental Lung Silicosis

1999 • 99 citations

Transforming Growth Factor-β Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis

1999 • 98 citations

Inhibition of Matrix Metalloproteinases by Lung TIMP-1 Gene Transfer or Doxycycline Aggravates Pulmonary Hypertension in Rats

2000 • 86 citations

Alterations in the Expression of Chemokine Mrna Levels in Fibrosis-Resistant and -Sensitive Mice After Thoracic Irradiation

1998 • 82 citations

Pathogenesis of lung fibrosis and potential new therapeutic strategies.

1995 • 80 citations

Reduced Tumor Necrosis Factor-α and Transforming Growth Factor-β1 Expression in the Lungs of Inbred Mice that Fail to Develop Fibroproliferative Lesions Consequent to Asbestos Exposure

1999 • 66 citations

PCR analysis of cytokine induction profiles associated with mouse strain variation in susceptibility to pulmonary fibrosis.

1993 • 55 citations

(Continued from previous page)

1946 • 37 citations

Radiation-Induced Pulmonary Endothelial Dysfunction and Hydroxyproline Accumulation in Four Strains of Mice

1989 • 32 citations

Mechanisms of Scarring

1996 • 5 citations