An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

High efficiency transformation of E.coli by high voltage electroporation

1988 • 2,789 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

A simple technique for the rescue of early region I mutations into infectious human adenovirus type 5

1988 • 606 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

Packaging capacity and stability of human adenovirus type 5 vectors

1993 • 457 citations

Expression of Heterologous Sequences in Adenoviral Vectors

1992 • 171 citations

Viability of λ phages carrying a perfect palindrome in the absence of recombination nucleases

1983 • 166 citations

Genome structure of incomplete particles of adenovirus

1976 • 145 citations

Vaccines. New approaches to immunological problems.

1992 • 144 citations

Generation of adenovirus by transfection of plasmids

1983 • 144 citations

Monitoring foreign gene expression by a human adenovirus-based vector using the firefly luciferase gene as a reporter

1993 • 141 citations

Protein IX, a minor component of the human adenovirus capsid, is essential for the packaging of full length genomes.

1987 • 134 citations

Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome

1987 • 134 citations

Encapsidation of adenovirus 16 DNA is directed by a small DNA sequence at the left end of the genome

1980 • 120 citations

The adenovirus type 5 E1A enhancer contains two functionally distinct domains: One is specific for E1A and the other modulates all early units in cis

1986 • 118 citations

DNA sequence of the early E3 transcription unit of adenovirus 5

1985 • 116 citations

Development of a helper-independent human adenovirus vector and its use in the transfer of the herpes simplex virus thymidine kinase gene

1986 • 113 citations

In vivo consequences of plasmid topology

1981 • 109 citations

cis and trans requirements for the selective packaging of adenovirus type 5 DNA

1992 • 108 citations

Covalently closed circles of human adenovirus DNA are infectious.

1984 • 98 citations

Adenovirus type 5 packaging domain is composed of a repeated element that is functionally redundant

1990 • 89 citations

Efficient adenoviral-mediated ornithine transcarbamylase expression in deficient mouse and human hepatocytes.

1993 • 85 citations

Human adenovirus cloning vectors based on infectious bacterial plasmids

1986 • 75 citations

Viral DNA sequences from incomplete particles of human adenovirus type 7

1977 • 75 citations

Abundant expression of herpes simplex virus glycoprotein gB using an adenovirus vector

1988 • 74 citations

Tn5 mutagenesis of the transforming genes of human adenovirus type 5

1982 • 68 citations

Covalently closed circles of adenovirus 5 DNA

1983 • 51 citations

Isolation and characterization of insertion mutants in E1A of adenovirus type 5

1991 • 30 citations

Promoter of the adenovirus polypeptide IX gene: similarity to E1B and inactivation by substitution of the simian virus 40 TATA element

1991 • 19 citations

Polarity in adenovirus recombination

1984 • 14 citations

Insertional mutagenesis using a synthetic lac operator

1989 • 10 citations