Analysis of Tumor Necrosis Factor- α , Lymphotoxin- α , Tumor Necrosis Factor Receptor II, and Interleukin-6 Polymorphisms in Patients with Idiopathic Pulmonary Fibrosis

Phototyping: comprehensive DNA typing for HLA‐A, B, C, DRB1, DRB3, DRB4, DRB5 & DQB1 by PCR with 144 primer mixes utilizing sequence‐specific primers (PCR‐SSP)

1995 • 1,018 citations

Genetic influence on cytokine production and fatal meningococcal disease

1997 • 814 citations

Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis.

1989 • 578 citations

Role of interleukin‐4 and interleukin‐10 in murine collagen‐induced arthritis. Protective effect of interleukin‐4 and interleukin‐10 treatment on cartilage destruction

1997 • 404 citations

Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.

1995 • 364 citations

Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure.

1993 • 329 citations

Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica

1993 • 210 citations

Polymorphism of the human TNF-α promoter — random variation or functional diversity?

1999 • 201 citations

Cytokine (TNFα, LTα and IL-10) polymorphisms in inflammatory bowel diseases and normal controls: differential effects on production and allele frequencies

2000 • 200 citations

IL‐6 and IL‐1β in Fever: Studies Using Cytokine‐Deficient (Knockout) Mice^a

1998 • 191 citations

Expression and localization of tumor necrosis factor-alpha and its mRNA in idiopathic pulmonary fibrosis.

1993 • 188 citations

Increased Risk of Fibrosing Alveolitis Associated with Interleukin-1 Receptor Antagonist and Tumor Necrosis Factor- α Gene Polymorphisms

2000 • 186 citations

Familial Idiopathic Pulmonary Fibrosis

1986 • 172 citations

TNF-α Receptor Knockout Mice Are Protected from the Fibroproliferative Effects of Inhaled Asbestos Fibers

1998 • 146 citations

Upregulation of the p75 But Not the p55 TNF- α Receptor mRNA after Silica and Bleomycin Exposure and Protection from Lung Injury in Double Receptor Knockout Mice

1999 • 122 citations

TNF and IL-6 mediate MIP-1alpha expression in bleomycin-induced lung injury.

1998 • 116 citations

TNF and IL-6 mediate MIP-1α expression in bleomycin-induced lung injury

1998 • 107 citations

Increased IL-6 and IL-8 in bronchoalveolar lavage fluids (BALF) from patients with sarcoidosis: correlation with the clinical parameters

1997 • 90 citations

IL-6 and IL-6 receptor modulation by IFN-gamma and tumor necrosis factor-alpha in human monocytic cell line (THP-1). Priming effect of IFN-gamma.

1991 • 85 citations

Expression of tumour necrosis factor‐α in cryptogenic fibrosing alveolitis

1993 • 76 citations

Polymerase chain reaction haplotyping using 3′ mismatches in the forward and reverse primers: application to the biallelic polymorphisms of tumor necrosis factor and lymphotoxin α

1997 • 69 citations

HLA-DRB1 * 03 , but not the TNFA -308 promoter gene polymorphism, confers protection against fistulising Crohn's disease

1998 • 64 citations

PCR analysis of cytokine induction profiles associated with mouse strain variation in susceptibility to pulmonary fibrosis.

1993 • 55 citations

p55 and p75 tumor necrosis factor receptors are expressed and mediate common functions in synovial fibroblasts and other fibroblasts.

1994 • 48 citations

Resistance of TNF/LTα double deficient mice to bleomycin‐induced fibrosis

1997 • 45 citations

Measurement of interleukin-6 in bronchoalveolar lavage fluid by radioimmunoassay: differences between patients with interstitial lung disease and control subjects

1991 • 43 citations

Polymorphic analysis of the high‐affinity tumor necrosis factor receptor 2

1999 • 29 citations

Is interleukin-6 important in inflammatory bowel disease?

2000 • 17 citations

Persistent Interleukin-2 Activity and Molecular Evidence for Expression of Lymphotoxin in the Hapten-Immune Model for Pulmonary Interstitial Fibrosis

1992 • 13 citations