Epstein-Barr Virus-Induced Resistance to Drugs That Activate the Mitotic Spindle Assembly Checkpoint in Burkitt's Lymphoma Cells

Persistence of the Epstein–Barr Virus and the Origins of Associated Lymphomas

2004 • 1,009 citations

Stuck in Division or Passing through

2004 • 630 citations

The role of BH3-only proteins in the immune system

2005 • 608 citations

Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death

2005 • 507 citations

FoxO3a Transcriptional Regulation of Bim Controls Apoptosis in Paclitaxel-treated Breast Cancer Cell Lines

2003 • 495 citations

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

2005 • 452 citations

Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines.

1993 • 309 citations

Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy

2004 • 289 citations

Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia

1991 • 234 citations

Epstein–Barr virus–associated Burkitt lymphomagenesis selects for downregulation of the nuclear antigen EBNA2

2002 • 223 citations

Silencing of the Novel p53 Target Gene Snk/Plk2 Leads to Mitotic Catastrophe in Paclitaxel (Taxol)-Exposed Cells

2003 • 216 citations

Epstein–Barr virus (EBV) LMP2A mediates B-lymphocyte survival through constitutive activation of the Ras/PI3K/Akt pathway

2004 • 200 citations

Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents

2004 • 166 citations

Molecular virology of Epstein–Barr virus

2001 • 148 citations

Activation of lytic Epstein-Barr virus (EBV) infection by radiation and sodium butyrate in vitro and in vivo: a potential method for treating EBV-positive malignancies.

2000 • 140 citations

Latent membrane protein 1 of Epstein–Barr virus coordinately regulates proliferation with control of apoptosis

2005 • 136 citations

Mitotic Catastrophe Results in Cell Death by Caspase-Dependentand Caspase-Independent Mechanisms

2005 • 133 citations

Transcriptional silencing of Polo-like kinase 2(SNK/PLK2)is a frequent event in B-cell malignancies

2005 • 121 citations

Epstein-Barr Virus Nuclear Antigen 2 (EBNA2) Gene Deletion Is Consistently Linked with EBNA3A, -3B, and -3C Expression in Burkitt's Lymphoma Cells and with Increased Resistance to Apoptosis

2005 • 109 citations

The great MYC escape in tumorigenesis

2005 • 109 citations

DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective.

1995 • 109 citations

Epstein-Barr virus efficiently immortalizes human B cells without neutralizing the function of p53.

1995 • 106 citations

Epstein-Barr virus EBNA3C can disrupt multiple cell cycle checkpoints and induce nuclear division divorced from cytokinesis

2000 • 104 citations

Activators of the Epstein-Barr Virus Lytic Program Concomitantly Induce Apoptosis, but Lytic Gene Expression Protects from Cell Death

2001 • 65 citations

The EBNA- 3 gene family proteins disrupt the G2/M checkpoint

2003 • 58 citations

EBV Infection of Human B Lymphocytes Leads to Down-Regulation of Bim Expression: Relationship to Resistance to Apoptosis

2005 • 53 citations

Epstein-Barr Virus Suppresses a G₂/M Checkpoint Activated by Genotoxins

2000 • 51 citations

EBNA2 Is Required for Protection of Latently Epstein-Barr Virus-Infected B Cells against Specific Apoptotic Stimuli

2004 • 42 citations

The Mitotic Checkpoint in Cancer Therapy

2005 • 36 citations

Epstein–Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2

2003 • 29 citations

Enhancement of genetic instability in human B cells by Epstein-Barr virus latent infection

2001 • 29 citations

Deregulation of the Cell Cycle by the Epstein–Barr Virus

2004 • 28 citations

Cell cycle arrest following exposure of EBV‐immortalised B‐cells to gamma irradiation correlates with inhibition of cdk2 activity

1998 • 14 citations

A HISTONE DEACETYLASE INHIBITOR, AZELAIC BISHYDROXAMIC ACID, SHOWS CYTOTOXICITY ON EPSTEIN-BARR VIRUS-TRANSFORMED B-CELL LINES

2002 • 12 citations