The great MYC escape in tumorigenesis

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

Transcriptional regulation and transformation by Myc proteins

2005 • 1,102 citations

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1999 • 828 citations

Bim is a suppressor of Myc-induced mouse B cell leukemia

2004 • 485 citations

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

2005 • 452 citations

Ras Enhances Myc Protein Stability

1999 • 452 citations

Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc

1999 • 427 citations

DNA and RNA from Uninfected Vertebrate Cells Contain Nucleotide Sequences Related to the Putative Transforming Gene of Avian Myelocytomatosis Virus

1979 • 273 citations

Phosphorylation sites mapping in the N-terminal domain of c-myc modulate its transforming potential.

1993 • 164 citations

A Link between Increased Transforming Activity of Lymphoma-Derived MYC Mutant Alleles, Their Defective Regulation by p107, and Altered Phosphorylation of the c-Myc Transactivation Domain

1995 • 142 citations