The Excitatory Amino Acid Transporter-2 Induces Apoptosis and Decreases Glioma Growth In vitro and In vivo

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Biochemical Pathways of Caspase Activation During Apoptosis

1999 • 2,567 citations

Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

1996 • 2,470 citations

Blockade of NMDA Receptors and Apoptotic Neurodegeneration in the Developing Brain

1999 • 2,023 citations

Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1

1997 • 1,715 citations

The RB and p53 pathways in cancer

2002 • 1,612 citations

Pathways of apoptotic and non-apoptotic death in tumour cells

2004 • 1,026 citations

Apoptotic Pathways

2000 • 993 citations

Cloning and Expression of a Plasma Membrane Cystine/Glutamate Exchange Transporter Composed of Two Distinct Proteins

1999 • 982 citations

Manipulation of Adenovirus Vectors

2003 • 780 citations

Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers.

1990 • 654 citations

Glutamate release promotes growth of malignant gliomas

2001 • 556 citations

The Annexins and Exocytosis

1992 • 549 citations

Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification.

1996 • 488 citations

Methods for construction of adenovirus vectors

1995 • 483 citations

The glutamate/neutral amino acid transporter family SLC1: molecular, physiological and pharmacological aspects

2004 • 430 citations

Glioma cells release excitotoxic concentrations of glutamate.

1999 • 420 citations

Neurotransmitters as early signals for central nervous system development

2001 • 364 citations

Compromised Glutamate Transport in Human Glioma Cells: Reduction–Mislocalization of Sodium-Dependent Glutamate Transporters and Enhanced Activity of Cystine–Glutamate Exchange

1999 • 339 citations

Roles of NMDA receptor activity and nitric oxide production in brain development

2000 • 337 citations

Blockage of Ca2+-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells

2002 • 307 citations

Glutamate antagonists limit tumor growth

2001 • 270 citations

Glutamate receptors in glia: new cells, new inputs and new functions

2000 • 239 citations

The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases

2004 • 231 citations

Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis

2004 • 172 citations

Ionotropic and metabotropic glutamate receptor protein expression in glioneuronal tumours from patients with intractable epilepsy

2001 • 144 citations

Baseline levels of glucose metabolites, glutamate and glycerol in malignant glioma assessed by stereotactic microdialysis.

2003 • 141 citations

Malignant gliomas: perverting glutamate and ion homeostasis for selective advantage

2003 • 124 citations

Tissue Microarrays: Applications in Neuropathology Research, Diagnosis, and Education

2002 • 121 citations

Cellular and Molecular Mechanisms of Cerebellar Granule Cell Migration

2002 • 96 citations

Extracellular glutamate and other metabolites in and around RG2 rat glioma: an intracerebral microdialysis study.

2000 • 92 citations

Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls

2000 • 91 citations

Neuron-like physiological properties of cells from human oligodendroglial tumors

1996 • 87 citations

Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells

2003 • 83 citations

The Role of Calcium in Pre- and Postmitochondrial Events in Tributyltin-Induced T-Cell Apoptosis

1999 • 63 citations

Cycloprodigiosin hydrochloride, H+/CL- symporter, induces apoptosis and differentiation in HL-60 cells

2000 • 52 citations

Apoptosis induction by E2F-1 via adenoviral-mediated gene transfer results in growth suppression of head and neck squamous cell carcinoma cell lines

1999 • 49 citations

Human Glioma Cells and Undifferentiated Primary Astrocytes That Express Aberrant EAAT2 mRNA Inhibit Normal EAAT2 Protein Expression and Prevent Cell Death

2002 • 40 citations

Expression of insulin‐like growth factor‐binding protein 2 in melanocytic lesions

2003 • 27 citations

Impaired RNA splicing of 5'-regulatory sequences of the astroglial glutamate transporter EAAT2 in human astrocytoma

2001 • 24 citations