Transcriptional repression by the insulator protein CTCF involves histone deacetylases

Nuclear Receptor Repression Mediated by a Complex Containing SMRT, mSin3A, and Histone Deacetylase

1997 • 1,251 citations

Retinoblastoma protein recruits histone deacetylase to repress transcription

1998 • 1,231 citations

A complex containing N-CoR, mSln3 and histone deacetylase mediates transcriptional repression

1997 • 1,218 citations

The Neuron-Restrictive Silencer Factor (NRSF): A Coordinate Repressor of Multiple Neuron-Specific Genes

1995 • 1,078 citations

The Protein CTCF Is Required for the Enhancer Blocking Activity of Vertebrate Insulators

1999 • 1,076 citations

Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression

1997 • 945 citations

Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

1997 • 856 citations

Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A

1997 • 739 citations

KAP-1, a novel corepressor for the highly conserved KRAB repression domain.

1996 • 637 citations

Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist

1989 • 599 citations

Mad-max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

1995 • 587 citations

Histone Deacetylases and SAP18, a Novel Polypeptide, Are Components of a Human Sin3 Complex

1997 • 565 citations

Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain.

1994 • 539 citations

An Exceptionally Conserved Transcriptional Repressor, CTCF, Employs Different Combinations of Zinc Fingers To Bind Diverged Promoter Sequences of Avian and Mammalian c-myc Oncogenes

1996 • 536 citations

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

1996 • 532 citations

ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

1998 • 525 citations

Aberrant Recruitment of the Nuclear Receptor Corepressor-Histone Deacetylase Complex by the Acute Myeloid Leukemia Fusion Partner ETO

1998 • 500 citations

Modular structure of a chicken lysozyme silencer: Involvement of an unusual thyroid hormone receptor binding site

1990 • 487 citations

CoREST: A functional corepressor required for regulation of neural-specific gene expression

1999 • 467 citations

Zinc fingers are sticking together

1998 • 464 citations

Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression

2000 • 409 citations

Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators

1998 • 403 citations

A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene.

1990 • 376 citations

Sin Meets NuRD and Other Tails of Repression

1999 • 353 citations

Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein

1997 • 343 citations

Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone.

1993 • 328 citations

Cloning and characterization of mCtBP2, a co-repressor that associates with basic Kruppel-like factor and other mammalian transcriptional regulators

1998 • 320 citations

The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT

1998 • 314 citations

The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth

1999 • 313 citations

A novel member of the RING finger family, KRIP-1, associates with the KRAB-A transcriptional repressor domain of zinc finger proteins

1996 • 278 citations

Transcriptional Repression by RING Finger Protein TIF1 That Interacts with the KRAB Repressor Domain of KOX1

1996 • 277 citations

CTCF, a Conserved Nuclear Factor Required for Optimal Transcriptional Activity of the Chicken c-myc Gene, Is an 11-Zn-Finger Protein Differentially Expressed in Multiple Forms

1993 • 271 citations

Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

1999 • 266 citations

The t4 Activation Domain of the Thyroid Hormone Receptor Is Required for Release of a Putative Corepressor(s) Necessary for Transcriptional Silencing

1995 • 250 citations

The LAZ3(BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression

1998 • 229 citations

A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1.

1993 • 223 citations

Stopped at the border: boundaries and insulators

1999 • 222 citations

The Zinc Finger Protein CTCF Binds to the APBβ Domain of the Amyloid β-Protein Precursor Promoter

1997 • 187 citations

Mad Proteins Contain a Dominant Transcription Repression Domain

1996 • 163 citations

A widely expressed transcription factor with multiple DNA sequence specificity,CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers

1998 • 142 citations

転写因子TF II Bとヒト甲状腺ホルモン受容体βとの結合は標的遺伝子の発現と甲状腺ホルモンによる活性化を仲介する

1993 • 135 citations

Negative Protein 1, Which Is Required for Function of the Chicken Lysozyme Gene Silencer in Conjunction with Hormone Receptors, Is Identical to the Multivalent Zinc Finger Repressor CTCF

1997 • 133 citations

The corepressor N-CoR and its variants RIP13a and RIP13 1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70

1998 • 128 citations

Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein.

1993 • 111 citations

Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses.

1992 • 110 citations

The carboxy‐terminal region of adenovirus E1A activates transcription through targeting of a C‐terminal binding protein‐histone deacetylase complex

1998 • 103 citations

hFOG-2, a Novel Zinc Finger Protein, Binds the Co-repressor mCtBP2 and Modulates GATA-mediated Activation

1999 • 102 citations

Transcriptional activity of the zinc finger protein NGFI-A is influenced by its interaction with a cellular factor.

1993 • 94 citations

An Element in the Region Responsible for Premature Termination of Transcription Mediates Repression of c-myc Gene Expression by Thyroid Hormone in Neuroblastoma Cells

2000 • 79 citations

Transcriptional Silencing Is Defined by Isoform- and Heterodimer-Specific Interactions between Nuclear Hormone Receptors and Corepressors

1998 • 74 citations

Negative Transcriptional Regulation Mediated by Thyroid Hormone Response Element 144 Requires Binding of the Multivalent Factor CTCF to a Novel Target DNA Sequence

1999 • 72 citations

A Novel Repression Module, an Extensive Activation Domain, and a Bipartite Nuclear Localization Signal Defined in the Immediate-Early Transcription Factor Egr-1

1993 • 66 citations

DNA Bending by the Silencer Protein NeP1 Is Modulated by TR and RXR

1996 • 51 citations

Novel location and function of a thyroid hormone response element.

1995 • 47 citations

Transcriptional Repression in Saccharomyces cerevisiae by a SIN3-LexA Fusion Protein

1993 • 41 citations

NeP1

1993 • 36 citations

Transcriptional Activity of the Zinc Finger Protein NGFI-A Is Influenced by Its Interaction with a Cellular Factor

1993 • 21 citations