Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain.

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

1964 • 2,410 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

1993 • 1,116 citations

A direct link between core histone acetylation and transcriptionally active chromatin.

1988 • 905 citations

A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

1993 • 858 citations

Chromatin as an essential part of the transcriptional mechanim

1992 • 853 citations

Transcriptional silencing in yeast is associated with reduced nucleosome acetylation.

1993 • 795 citations

The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression

1993 • 692 citations

A position-effect assay for boundaries of higher order chromosomal domains

1991 • 616 citations

Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nuclei

1992 • 552 citations

Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I

1980 • 486 citations

Alternative chromatin structure at CpG islands

1990 • 480 citations

Histone Function in Transcription

1990 • 354 citations

Histone acetylation and control of gene expression

1991 • 331 citations

Yeast histone H4 N-terminal sequence is required for promoter activation in vivo

1991 • 330 citations

The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain.

1988 • 280 citations

Participation of core histone "tails" in the stabilization of the chromatin solenoid.

1982 • 264 citations

Chromatin Structure and Transcription

1992 • 259 citations

On the biological role of histone acetylation

1990 • 246 citations

Two-Dimensional Gel Analysis of Histones in Acid Extracts of Nuclei, Cells, and Tissues

1980 • 242 citations

Histone H3 N-terminal mutations allow hyperactivation of the yeast GAL1 gene in vivo.

1992 • 186 citations

Chromatin structure of transcriptionally competent and repressed genes.

1990 • 178 citations

Definition of 5‘ and 3‘ structural boundaries of the chromatin domain containing the ovalbumin multigene family.

1982 • 172 citations

The limits of the DNase I-sensitive domain of the human apolipoprotein B gene coincide with the locations of chromosomal anchorage loops and define the 5′ and 3′ boundaries of the gene

1989 • 139 citations

Histone acetylation and globin gene switching

1992 • 111 citations

Developmental Regulation of Topoisomerase II Sites and DNase I-Hypersensitive Sites in the Chicken β-Globin Locus

1990 • 108 citations

Chromatin structure of the chicken beta-globin gene region. Sensitivity to DNase I, micrococcal nuclease, and DNase II.

1982 • 92 citations

The DNase I sensitive domain of the chicken Iysozyme gene spans 24 kb

1986 • 88 citations

Chromatin structure of the chicken lysozyme gene domain as determined by chromatin fractionation and micrococcal nuclease digestion

1986 • 74 citations

Histone acetylation and gene induction in human cells

1993 • 54 citations

The chicken beta globin gene region. Delineation of transcription units and developmental regulation of interspersed DNA repeats.

1982 • 51 citations

A “minimal epitope” anti-protein antibody that recognises a single modified amino acid

1989 • 38 citations