Kaposi's Sarcoma-Associated Herpesvirus Mitochondrial K7 Protein Targets a Cellular Calcium-Modulating Cyclophilin Ligand To Modulate Intracellular Calcium Concentration and Inhibit Apoptosis

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1997 • 7,177 citations

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Identification of Herpesvirus-Like DNA Sequences in AIDS-Sssociated Kaposi's Sarcoma

1994 • 5,605 citations

The versatility and universality of calcium signalling

2000 • 5,407 citations

Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+

1995 • 5,025 citations

Molecular characterization of mitochondrial apoptosis-inducing factor

1999 • 4,031 citations

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

2000 • 3,415 citations

Two CD95 (APO-1/Fas) signaling pathways

1998 • 3,045 citations

Kaposi's Sarcoma–Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity–Based Lymphomas

1995 • 2,833 citations

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease [see comments]

1995 • 2,169 citations

High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier

1989 • 2,140 citations

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca ²⁺ Responses

1998 • 2,130 citations

Calcium - a life and death signal

1998 • 2,040 citations

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

1996 • 1,464 citations

Organelle-specific initiation of cell death pathways

2001 • 1,454 citations

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

2001 • 1,327 citations

NFAT Signaling

2002 • 1,316 citations

TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS

1999 • 1,309 citations

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c

2000 • 994 citations

Apoptotic Pathways

2000 • 993 citations

Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHV

1996 • 926 citations

Mitochondria as regulators of apoptosis: doubt no more

1998 • 838 citations

Viral Subversion of the Immune System

2000 • 833 citations

Calcium and oxidative stress: from cell signaling to cell death

2002 • 803 citations

Two Distinct Pathways Leading to Nuclear Apoptosis

2000 • 737 citations

Complete sequence and genomic analysis of murine gammaherpesvirus 68

1997 • 736 citations

Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells

1995 • 692 citations

Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen

1996 • 639 citations

Glutamate-induced neuron death requires mitochondrial calcium uptake

1998 • 623 citations

The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action

2001 • 578 citations

Mitochondria as all‐round players of the calcium game

2000 • 556 citations

Mechanisms of capacitative calcium entry

2001 • 536 citations

Control of Programmed Cell Death by the Baculovirus Genes p35 and iap

1994 • 517 citations

Angiogenic and HIV-Inhibitory Functions of KSHV-Encoded Chemokines

1997 • 479 citations

A Bcl-2 homolog encoded by Kaposi sarcoma-associated virus, human herpesvirus 8, inhibits apoptosis but does not heterodimerize with Bax or Bak

1997 • 437 citations

Bcl-2 decreases the free Ca ²⁺ concentration within the endoplasmic reticulum

2000 • 417 citations

Kinetics of Kaposi’s Sarcoma-Associated Herpesvirus Gene Expression

1999 • 396 citations

Calcium Signaling by HBx Protein in Hepatitis B Virus DNA Replication

2001 • 382 citations

NF-AT Activation Induced by a CAML-Interacting Member of the Tumor Necrosis Factor Receptor Superfamily

1997 • 377 citations

Kaposi's sarcoma-associated herpesvirus encodes a functional Bcl-2 homologue

1997 • 352 citations

Maintenance of Calcium Homeostasis in the Endoplasmic Reticulum by Bcl-2

1997 • 296 citations

Deregulation of cell growth by the K1 gene of Karposi's sarcoma-associated herpesvirus

1998 • 290 citations

Mitochondria Recycle Ca2+ to the Endoplasmic Reticulum and Prevent the Depletion of Neighboring Endoplasmic Reticulum Regions

2001 • 262 citations

Cell Death Inhibition

2001 • 253 citations

Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells.

1996 • 240 citations

KSHV and Kaposi's Sarcoma: The End of the Beginning?

1997 • 223 citations

Calcium signaling in the cell nucleus

1997 • 208 citations

Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells

1998 • 203 citations

Transient Receptor Potential 1 Regulates Capacitative Ca2+ Entry and Ca2+ Release from Endoplasmic Reticulum in B Lymphocytes

2002 • 203 citations

The Primary Sequence of Rhesus Monkey Rhadinovirus Isolate 26-95: Sequence Similarities to Kaposi's Sarcoma-Associated Herpesvirus and Rhesus Monkey Rhadinovirus Isolate 17577

2000 • 183 citations

Calcium Regulates the Association between Mitochondria and a Smooth Subdomain of the Endoplasmic Reticulum

2000 • 173 citations

Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin

2002 • 163 citations

Calcium signalling in T cells stimulated by a cyclophilin B-binding protein

1994 • 162 citations

The apoptotic v-cyclin–CDK6 complex phosphorylates and inactivates Bcl-2

2000 • 160 citations

Capacitative Calcium Entry Contributes to Nuclear Factor of Activated T-cells Nuclear Translocation and Hypertrophy in Cardiomyocytes

2002 • 157 citations

Deregulated signal transduction by the K1 gene product of Kaposi’s sarcoma-associated herpesvirus

1999 • 157 citations

Antiapoptotic Herpesvirus Bcl-2 Homologs Escape Caspase-Mediated Conversion to Proapoptotic Proteins

2000 • 137 citations

M11l

2000 • 131 citations

A Splice-Isoform of Vesicle-associated Membrane Protein-1 (VAMP-1) Contains a Mitochondrial Targeting Signal

1998 • 131 citations

The comeback of mitochondria to calcium signalling

2000 • 106 citations

Viral interference with apoptosis

1998 • 105 citations

Inhibition of Intracellular Transport of B Cell Antigen Receptor Complexes by Kaposi's Sarcoma–Associated Herpesvirus K1

2000 • 103 citations

Sorting of calcium signals at the junctions of endoplasmic reticulum and mitochondria

2001 • 96 citations

Epstein-Barr Virus BALF1 Is a BCL-2-Like Antagonist of the Herpesvirus Antiapoptotic BCL-2 Proteins

2002 • 94 citations

Mitochondrial Control of Cell Death Induced by HIV‐1‐Encoded Proteins

2000 • 83 citations

Hydrophobic residues within the predicted N‐terminal amphiphilic α‐helix of a plant mitochondrial targeting presequence play a major role in in vivo import

2001 • 69 citations

Role of Calcium in Glucocorticosteroid-Induced Apoptosis of Thymocytes and Lymphoma Cells: Resurrection of Old Theories by New Findings

1998 • 66 citations

BHRF1, a viral homologue of the Bcl-2 oncogene, is conserved at both the sequence and functional level in different Epstein-Barr virus isolates.

1997 • 63 citations

Analysis of Plasminogen-Binding M Proteins of Streptococcus pyogenes

2000 • 58 citations

Signaling Activities of Gammaherpesvirus Membrane Proteins

2000 • 58 citations

Role of Calcium in Glucocorticosteroid-Induced Apoptosis of Thymocytes and Lymphoma Cells: Resurrection of Old Theories by New Findings

1998 • 58 citations

Interaction of an adenovirus 14.7-kilodalton protein inhibitor of tumor necrosis factor alpha cytolysis with a new member of the GTPase superfamily of signal transducers

1997 • 57 citations

Herpesvirus Saimiri vFLIP Provides an Antiapoptotic Function but Is Not Essential for Viral Replication, Transformation, or Pathogenicity

2000 • 49 citations

Identification and Characterization of a Mitochondrial Targeting Signal in Rat Cytochrome P450 2E1 (CYP2E1)

2001 • 46 citations

Murine gammaherpesvirus M11 gene product inhibits apoptosis and is expressed during virus persistence

2000 • 42 citations

Viral Caspase Inhibitors CrmA and p35

2000 • 38 citations

A Hydrophobic Domain of Ca -modulating Cyclophilin Ligand Modulates Calcium Influx Signaling in T Lymphocytes

1996 • 32 citations

Hot at the Center

1995 • 4 citations