The comeback of mitochondria to calcium signalling

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism

1961 • 4,416 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca ²⁺ Responses

1998 • 2,130 citations

Microdomains with High Ca ²⁺ Close to IP ₃ -Sensitive Channels that Are Sensed by Neighboring Mitochondria

1993 • 1,167 citations

Molecular and cellular physiology of intracellular calcium stores

1994 • 1,132 citations

Decoding of cytosolic calcium oscillations in the mitochondria

1995 • 1,090 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

A further Contribution regarding the influence of the different Constituents of the Blood on the Contraction of the Heart

1883 • 941 citations

Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

1992 • 920 citations

Regulation of mitochondrial ATP synthesis by calcium: Evidence for a long-term metabolic priming

1999 • 776 citations

On cytochrome, a respiratory pigment, common to animals, yeast, and higher plants

1925 • 533 citations

Mitochondrial Regulation of Store-operated Calcium Signaling in T Lymphocytes

1997 • 513 citations

Mitochondria buffer physiological calcium loads in cultured rat dorsal root ganglion neurons

1994 • 494 citations

Synchronization of calcium waves by mitochondrial substrates in Xenopus laevis oocytes

1995 • 425 citations

Molecular model for receptor-stimulated calcium spiking.

1988 • 416 citations

Regulation of the intracellular free calcium concentration in single rat dorsal root ganglion neurones in vitro.

1990 • 410 citations

Cytochrome and cytochrome oxidase

1939 • 399 citations

Integrating cytosolic calcium signals into mitochondrial metabolic responses

1998 • 373 citations

Active mitochondria surrounding the pancreatic acinar granule region prevent spreading of inositol trisphosphate-evoked local cytosolic Ca2+ signals

1999 • 362 citations

Calcium content of mitochondria and endoplasmic reticulum in liver frozen rapidly in vivo

1985 • 356 citations

Cloning and sequence analysis of cDNA for the luminescent protein aequorin.

1985 • 324 citations

Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells.

1995 • 308 citations

Highly Cooperative Opening of Calcium Channels by Inositol 1,4,5-Trisphosphate

1988 • 307 citations

The Role of Citric Acid in Intermediate Metabolism in Animal Tissues

1968 • 292 citations

Electron probe analysis of vascular smooth muscle. Composition of mitochondria, nuclei, and cytoplasm.

1979 • 263 citations

Mitochondria Suppress Local Feedback Activation of Inositol 1,4,5-Trisphosphate Receptors by Ca2+

1999 • 261 citations

Mechanisms for Intracellular Calcium Regulation in Heart

1973 • 253 citations

Die vitale Färbung, eine Darstellungsmethode der Zellgranula

1899 • 145 citations

VI. Researches on myohamatin and the histohæmatins

1886 • 111 citations

Inositol 1,4,5-trisphosphate and intracellular Ca2+ homeostasis in clonal pituitary cells (GH3). Translocation of Ca2+ into mitochondria from a functionally discrete portion of the nonmitochondrial store.

1986 • 80 citations

Quantitative Analysis of Mitochondrial Ca2+ Uptake and Release Pathways in Sympathetic Neurons

2000 • 67 citations

Control of InsP₃‐induced Ca²⁺ oscillations in permeabilized blowfly salivary gland cells: contribution of mitochondria

2000 • 53 citations

Determination of mitochondrial calcium content in hepatocytes by a rapid cellular fractionation technique. Vasopressin stimulates mitochondrial Ca2+ uptake

1984 • 37 citations