Control of gene expression through regulation of the TATA-binding protein

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

1998 • 1,660 citations

Crystal structure of a yeast TBP/TATA-box complex

1993 • 1,082 citations

Co-crystal structure of TBP recognizing the minor groove of a TATA element

1993 • 1,039 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

Structure and Function of a Human TAF _II 250 Double Bromodomain Module

2000 • 808 citations

BIOCHEMISTRY AND STRUCTURAL BIOLOGY OF TRANSCRIPTION FACTOR IID (TFIID)

1996 • 721 citations

The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity

1996 • 705 citations

TBP, a universal eukaryotic transcription factor?

1993 • 642 citations

Transcription from a TATA-less promoter requires a multisubunit TFIID complex.

1991 • 618 citations

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

1993 • 589 citations

Acetylation of general transcription factors by histone acetyltransferases

1997 • 588 citations

Molecular Genetics of the RNA Polymerase II General Transcriptional Machinery

1998 • 557 citations

Crystal structure of a TFIIB–TBP–TATA-element ternary complex

1995 • 542 citations

Histone-like TAFs within the PCAF Histone Acetylase Complex

1998 • 534 citations

Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

1998 • 490 citations

The downstream core promoter element, DPE, is conserved fromDrosophila to humans and is recognized by TAF_II60 of Drosophila

1997 • 487 citations

Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme

1999 • 457 citations

p53 Transcriptional Activation Mediated by Coactivators TAF _II 40 and TAF _II 60

1995 • 438 citations

A Subset of TAFIIs Are Integral Components of the SAGA Complex Required for Nucleosome Acetylation and Transcriptional Stimulation

1998 • 419 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

Crystal structure of TFIID TATA-box binding protein

1992 • 410 citations

Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

1994 • 402 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

Assembly of recombinant TFIID reveals differential coactivator requirements for distinct transcriptional activators

1994 • 374 citations

RNA Polymerase II Holoenzyme Contains SWI/SNF Regulators Involved in Chromatin Remodeling

1996 • 364 citations

Redundant roles for the TFIID and SAGA complexes in global transcription

2000 • 360 citations

Functional Organization of the Yeast SAGA Complex: Distinct Components Involved in Structural Integrity, Nucleosome Acetylation, and TATA-Binding Protein Interaction

1999 • 358 citations

Crystal structure of a yeast TFIIA/TBP/DNA complex

1996 • 312 citations

Human TAFII31 protein is a transcriptional coactivator of the p53 protein.

1995 • 297 citations

Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism.

1994 • 294 citations

TBP-associated factors are not generally required for transcriptional activation in yeast

1996 • 289 citations

TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA

1994 • 275 citations

Crystal Structure of the Yeast TFIIA/TBP/DNA Complex

1996 • 263 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1995 • 262 citations

Structural similarity between TAFs and the heterotetrameric core of the histone octamer

1996 • 258 citations

Function of TAFII-containing complex without TBP in transcription by RNA polymerase II

1998 • 252 citations

TBP-TAF complexes: selectivity factors for eukaryotic transcription

1994 • 250 citations

The role of the TATA-binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB

1992 • 241 citations

Transcription activation in cells lacking TAFIIs

1996 • 238 citations

Enhancement of TBP binding by activators and general transcription factors

1999 • 237 citations

Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation

1993 • 234 citations

The Something About Silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF_II30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)–FACT complex

2000 • 221 citations

SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae.

1992 • 217 citations

Drosophila TAF _II 150: Similarity to Yeast Gene TSM-1 and Specific Binding to Core Promoter DNA

1994 • 212 citations

The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively

1998 • 207 citations

Solution Structure of a TBP–TAFII230 Complex

1998 • 203 citations

Bromodomain factor 1 corresponds to a missing piece of yeast TFIID

2000 • 200 citations

NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization.

1994 • 199 citations

TAFII250 Is a Bipartite Protein Kinase That Phosphorylates the Basal Transcription Factor RAP74

1996 • 194 citations

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain

1995 • 188 citations

The p250 subunit of native TATA box-binding factor TFIID is the cell-cycle regulatory protein CCG1

1993 • 185 citations

Distinct Classes of Yeast Promoters Revealed by Differential TAF Recruitment

2000 • 183 citations

A histone octamer-like structure within TFIID

1996 • 182 citations

Identification of TATA-binding Protein-free TAFII-containing Complex Subunits Suggests a Role in Nucleosome Acetylation and Signal Transduction

1999 • 181 citations

Regulation of gene expression by TBP-associated proteins

1998 • 181 citations

Yeast TAFII145 Functions as a Core Promoter Selectivity Factor, Not a General Coactivator

1997 • 179 citations

A Human SPT3-TAFII31-GCN5-L Acetylase Complex Distinct from Transcription Factor IID

1998 • 179 citations

TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family

1999 • 179 citations

Largest subunit of Drosophila transcription factor IID directs assembly of a complex containing TBP and a coactivator

1993 • 176 citations

TAF-Containing and TAF-Independent Forms of Transcriptionally Active TBP in Vivo

2000 • 173 citations

Transcription Properties of a Cell Type–Specific TATA-Binding Protein, TRF

1997 • 170 citations

Human TAFII105 Is a Cell Type–Specific TFIID Subunit Related to hTAFII130

1996 • 169 citations

Yeast TAF IIS in a multisubunit complex required for activated transcription

1994 • 163 citations

Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo

1995 • 161 citations

TFG3/TAF30/ANC1, a Component of the Yeast SWI/SNF Complex That Is Similar to the Leukemogenic Proteins ENL and AF-9

1996 • 158 citations

A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains.

1996 • 158 citations

An ATP-dependent inhibitor of TBP binding to DNA.

1993 • 156 citations

A Class of Activation Domains Interacts Directly with TFIIA and Stimulates TFIIA-TFIID-Promoter Complex Assembly

1995 • 152 citations

Human TAFII28 and TAFII18 Interact through a Histone Fold Encoded by Atypical Evolutionary Conserved Motifs Also Found in the SPT3 Family

1998 • 151 citations

Molecular cloning of the small (gamma) subunit of human TFIIA reveals functions critical for activated transcription.

1994 • 151 citations

The CCR4 and CAF1 Proteins of the CCR4-NOT Complex Are Physically and Functionally Separated from NOT2, NOT4, and NOT5

1999 • 150 citations

TFIIF-TAF-RNA polymerase II connection.

1994 • 148 citations

Three-Dimensional Structure of the Human TFIID-IIA-IIB Complex

1999 • 142 citations

Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells.

1997 • 141 citations

Assembly of the isomerized TFIIA--TFIID--TATA ternary complex is necessary and sufficient for gene activation.

1996 • 136 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification and Analysis of Transcription Factor ILA and Identification of Transcription Factor IIJ

1992 • 136 citations

A TBP–TAF complex required for transcription of human snRNA genes by RNA polymerases II and III

1995 • 135 citations

RNA Polymerase II Holoenzyme Recruitment Is Sufficient to Remodel Chromatin at the Yeast PHO5 Promoter

1997 • 133 citations

Inhibition of TATA-Binding Protein Function by SAGA Subunits Spt3 and Spt8 at Gcn4-Activated Promoters

2000 • 130 citations

Molecular cloning and analysis of two subunits of the human TFIID complex: hTAF _II 130 and hTAF _II 100

1996 • 130 citations

A new factor related to TATA-binding protein has highly restricted expression patterns in Drosophila

1993 • 127 citations

Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.

1995 • 126 citations

Gene activation by recruitment of the RNA polymerase II holoenzyme.

1996 • 123 citations

Reconstitution of transcription with five purified initiation factors and RNA polymerase II from Saccharomyces cerevisiae

1992 • 121 citations

Three-Dimensional Structures of the TAF _II -Containing Complexes TFIID and TFTC

1999 • 120 citations

Structure and function of a human transcription factor TFIIIB subunit that is evolutionarily conserved and contains both TFIIB- and high-mobility-group protein 2-related domains.

1995 • 120 citations

The Yeast TAF145 Inhibitory Domain and TFIIA Competitively Bind to TATA-Binding Protein

1998 • 119 citations

Human TATA-binding protein-related factor-2 (hTRF2) stably associates with hTFIIA in HeLa cells

1999 • 119 citations

Activator-Mediated Recruitment of the RNA Polymerase II Machinery Is the Predominant Mechanism for Transcriptional Activation in Yeast

1998 • 118 citations

Photofootprinting in vivo detects transcription-dependent changes in yeast TATA boxes

1987 • 117 citations

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.

1994 • 116 citations

Molecular cloning and expression of the 32-kDa subunit of human TFIID reveals interactions with VP16 and TFIIB that mediate transcriptional activation.

1995 • 116 citations

Molecular cloning of Drosophila TFIID subunits

1994 • 114 citations

The dTAFII80 subunit of Drosophila TFIID contains β-transducin repeats

1993 • 114 citations

Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.

1995 • 114 citations

Functional Interaction between p53, the TATA-Binding Protein (TBP), and TBP-Associated Factors In Vivo

1996 • 112 citations

Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex.

1993 • 110 citations

Promoter-Selective Properties of the TBP-Related Factor TRF1

2000 • 109 citations

TAFs and TFIIA mediate differential utilization of the tandem Adh promoters

1995 • 108 citations

Recruiting TATA-Binding Protein to a Promoter: Transcriptional Activation without an Upstream Activator

1995 • 108 citations

The NOT, SPT3, and MOT1 Genes Functionally Interact To Regulate Transcription at Core Promoters

1996 • 108 citations

Mechanism of Initiator-Mediated Transcription: Evidence for a Functional Interaction between the TATA-Binding Protein and DNA in the Absence of a Specific Recognition Sequence

1993 • 104 citations

A TRF1:BRF Complex Directs Drosophila RNA Polymerase III Transcription

2000 • 102 citations

Interplay of Positive and Negative Regulators in Transcription Initiation by RNA Polymerase II Holoenzyme

1998 • 102 citations

2.1 Å resolution refined structure of a TATA box-binding protein (TBP)

1994 • 102 citations

A Human TATA Binding Protein-Related Protein with Altered DNA Binding Specificity Inhibits Transcription from Multiple Promoters and Activators

1999 • 100 citations

Drosophila 230-kD TFIID subunit, a functional homolog of the human cell cycle gene product, negatively regulates DNA binding of the TATA box-binding subunit of TFIID.

1993 • 97 citations

Broad, but Not Universal, Transcriptional Requirement for yTAFII17, a Histone H3–like TAFII Present in TFIID and SAGA

1998 • 94 citations

Yeast homologues of higher eukaryotic TFIID subunits

1996 • 93 citations

The Human TFIID Components TAF_II135 and TAF_II20 and the Yeast SAGA Components ADA1 and TAF_II68 Heterodimerize to Form Histone-Like Pairs

2000 • 93 citations

Distinct domains of hTAFII100 are required for functional interaction with transcription factor TFIIF beta (RAP30) and incorporation into the TFIID complex.

1996 • 87 citations

TBP mutants defective in activated transcription in vivo.

1995 • 87 citations

Molecular cloning of the cDNA of human X chromosomal gene (CCG1) which complements the temperature-sensitive G1 mutants, tsBN462 and ts13, of the BHK cell line.

1988 • 86 citations

Saccharomyces cerevisiae BUR6Encodes a DRAP1/NC2α Homolog That Has both Positive and Negative Roles in Transcription In Vivo

1997 • 86 citations

Dimerization of the TATA Binding Protein

1995 • 86 citations

Identification of a mouse TBP-like protein (TLP) distantly related to the Drosophila TBP-related factor

1999 • 85 citations

Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.

1996 • 83 citations

Identification of a General Transcription Factor TFIIAα/β Homolog Selectively Expressed in Testis

1999 • 78 citations

Identification of Two Novel TAF Subunits of the YeastSaccharomyces cerevisiae TFIID Complex

2000 • 76 citations

Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors.

1995 • 75 citations

Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription.

1995 • 73 citations

Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID.

1993 • 71 citations

A Role for TBP Dimerization in Preventing Unregulated Gene Expression

1999 • 71 citations

The viral oncoproteins Ad5 E1A, HPV16 E7 and SV40 TAg bind a common region of the TBP-associated factor-110.

1995 • 68 citations

Novel Cofactors and TFIIA Mediate Functional Core Promoter Selectivity by the Human TAF_II150-Containing TFIID Complex

1998 • 68 citations

Dimerization of TFIID When Not Bound to DNA

1996 • 68 citations

Cloning and Biochemical Characterization of TAF-172, a Human Homolog of Yeast Mot1

1998 • 67 citations

Two Novel Drosophila TAF_IIs Have Homology with Human TAF_II30 and Are Differentially Regulated during Development

2000 • 67 citations

Structure-Function Analysis of TAF130: Identification and Characterization of a High-Affinity TATA-Binding Protein Interaction Domain in the N Terminus of Yeast TAF_II130

1997 • 66 citations

Requirement for TAF_II250 Acetyltransferase Activity in Cell Cycle Progression

2000 • 64 citations

Isolation and Characterization of TAF25, an Essential Yeast Gene That Encodes an RNA Polymerase II-specific TATA-binding Protein-associated Factor

1996 • 64 citations

Cyclin D1 Associates with the TBP-associated factor TAFII250 to regulate Sp1-mediated transcription

1999 • 64 citations

CIF150, a Human Cofactor for Transcription Factor IID-Dependent Initiator Function

1998 • 63 citations

A new regulatory domain on the TATA-binding protein

1999 • 61 citations

MOT1 Can Activate Basal Transcription In Vitro by Regulating the Distribution of TATA Binding Protein between Promoter and Nonpromoter Sites

1999 • 60 citations

Factors involved in specific transcription by mammalian RNA polymerase II: purification and analysis of transcription factor IIA and identification of transcription factor IIJ.

1992 • 60 citations

Transcription Factor IIA Derepresses TATA-binding Protein (TBP)-associated Factor Inhibition of TBP-DNA Binding

1998 • 60 citations

Human TAFII250 interacts with RAP74: implications for RNA polymerase II initiation.

1995 • 59 citations

A Testis-specific Transcription Factor IIA (TFIIAτ) Stimulates TATA-binding Protein-DNA Binding and Transcription Activation

2000 • 59 citations

Slow dimer dissociation of the TATA binding protein dictates the kinetics of DNA binding

1997 • 58 citations

Cloning and Characterization of Human TAF20/15

1996 • 57 citations

Involvement of Negative Cofactor NC2 in Active Repression by Zinc Finger-Homeodomain Transcription Factor AREB6

1998 • 55 citations

Molecular cloning and characterization of dTAFII30 alpha and dTAFII30 beta: two small subunits of Drosophila TFIID.

1993 • 54 citations

The CREB Constitutive Activation Domain Interacts with TATA-binding Protein-associated Factor 110 (TAF110) through Specific Hydrophobic Residues in One of the Three Subdomains Required for Both Activation and TAF110 Binding

1999 • 53 citations

A single point mutation in TFIIA suppresses NC2 requirement in vivo

2000 • 52 citations

Human TAF_II55 Interacts with the Vitamin D₃ and Thyroid Hormone Receptors and with Derivatives of the Retinoid X Receptor That Have Altered Transactivation Properties

1999 • 50 citations

Multiple Interactions between hTAFII55 and Other TFIID Subunits

1996 • 48 citations

Specific Interactions and Potential Functions of Human TAFII100

1997 • 47 citations

Mechanism of initiator-mediated transcription: evidence for a functional interaction between the TATA-binding protein and DNA in the absence of a specific recognition sequence.

1993 • 45 citations

TFIIA Regulates TBP and TFIID Dimers

1999 • 44 citations

Identification of a Yeast Transcription Factor IID Subunit, TSG2/TAF48

2000 • 39 citations

Transcriptional Functions of a New Mammalian TATA-binding Protein-related Factor

1999 • 39 citations

Molecular Cloning, Expression, and Characterization of the Drosophila 85-Kilodalton TFIID Subunit

1993 • 39 citations

Functional Dissection of a Human Dr1-DRAP1 Repressor Complex

1997 • 35 citations

The Human Transcription Factor IID Subunit Human TATA-binding Protein-associated Factor 28 Interacts in a Ligand-reversible Manner with the Vitamin D3 and Thyroid Hormone Receptors

2000 • 22 citations

The TSM1 gene of Saccharomyces cerevisiae overlaps the MAT locus

1991 • 20 citations

Molecular cloning, expression, and characterization of the Drosophila 85-kilodalton TFIID subunit.

1993 • 16 citations

TATA-Binding Protein Mutants That Increase Transcription from Enhancerless and Repressed Promoters In Vivo

2000 • 16 citations

In Vitro Transcription of a TATA-Less Promoter: Negative Regulation by the Not1 Protein

1999 • 10 citations