TFIIA Regulates TBP and TFIID Dimers

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The general transcription factors of RNA polymerase II.

1996 • 1,010 citations

Transcription from a TATA-less promoter requires a multisubunit TFIID complex.

1991 • 618 citations

Molecular Genetics of the RNA Polymerase II General Transcriptional Machinery

1998 • 557 citations

Crystal structure of TFIID TATA-box binding protein

1992 • 410 citations

A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives

1990 • 386 citations

DNA topoisomerase I is involved in both repression and activation of transcription

1993 • 380 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID

1992 • 195 citations

An ATP-dependent inhibitor of TBP binding to DNA.

1993 • 156 citations

The TATA-binding protein and associated factors are components of pol III transcription factor TFIIIB

1992 • 156 citations

A Class of Activation Domains Interacts Directly with TFIIA and Stimulates TFIIA-TFIID-Promoter Complex Assembly

1995 • 152 citations

TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters.

1992 • 151 citations

Crystal structure of yeast TATA-binding protein and model for interaction with DNA.

1993 • 150 citations

Isolation of Two Genes That Encode Subunits of the Yeast Transcription Factor IIA

1992 • 137 citations

Assembly of the isomerized TFIIA--TFIID--TATA ternary complex is necessary and sufficient for gene activation.

1996 • 136 citations

The TBP-TFIIA Interaction in the Response to Acidic Activators in Vivo

1995 • 132 citations

The Yeast TAF145 Inhibitory Domain and TFIIA Competitively Bind to TATA-Binding Protein

1998 • 119 citations

Reconstitution of human TFIIA activity from recombinant polypeptides: a role in TFIID-mediated transcription.

1994 • 116 citations

Evidence for Functional Binding and Stable Sliding of the TATA Binding Protein on Nonspecific DNA

1995 • 116 citations

Increased Recruitment of TATA-Binding Protein to the Promoter by Transcriptional Activation Domains in Vivo

1994 • 114 citations

The yeast general transcription factor TFIIA is composed of two polypeptide subunits.

1991 • 110 citations

Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex.

1993 • 110 citations

Drosophila TFIIA directs cooperative DNA binding with TBP and mediates transcriptional activation.

1994 • 103 citations

Radical mutations reveal TATA-box binding protein surfaces required for activated transcription in vivo.

1996 • 97 citations

Dimerization of the TATA Binding Protein

1995 • 86 citations

A Role for TBP Dimerization in Preventing Unregulated Gene Expression

1999 • 71 citations

Dimerization of TFIID When Not Bound to DNA

1996 • 68 citations

Cloning and Biochemical Characterization of TAF-172, a Human Homolog of Yeast Mot1

1998 • 67 citations

Transcription Factor IIA Derepresses TATA-binding Protein (TBP)-associated Factor Inhibition of TBP-DNA Binding

1998 • 60 citations

Slow dimer dissociation of the TATA binding protein dictates the kinetics of DNA binding

1997 • 58 citations

Dynamic interplay of TFIIA, TBP and TATA DNA

1997 • 58 citations

Dimer Dissociation and Thermosensitivity Kinetics of the Saccharomyces cerevisiae and Human TATA Binding Proteins

1999 • 17 citations