Attenuated Shigella flexneri 2a Vaccine Strain CVD 1204 Expressing Colonization Factor Antigen I and Mutant Heat-Labile Enterotoxin of Enterotoxigenic Escherichia coli
Data up to Jan 2025
Total Citations Per Year
Abstract
References (62)
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
1979 • 15,511 citations
Bacterial lipopolysaccharides : extraction with phenol-water and further applications of the procedure
1965 • 2,566 citations
A RAPID ALKALINE EXTRACTION PROCEDURE FOR SCREENING RECOMBINANT DNA
1979 • 1,402 citations
Escherichia coli that Cause Diarrhea: Enterotoxigenic, Enteropathogenic, Enteroinvasive, Enterohemorrhagic, and Enteroadherent
1987 • 1,279 citations
New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development
1983 • 573 citations
Cross-Protection by B Subunit-Whole Cell Cholera Vaccine Against Diarrhea Associated with Heat-Labile Toxin-Producing Enterotoxigenic Escherichia coli: Results of a Large-Scale Field Trial
1988 • 342 citations
Occurrence, distribution, and associations of O and H serogroups, colonization factor antigens, and toxins of enterotoxigenic Escherichia coli
1997 • 306 citations
Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants.
1995 • 288 citations
Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins
1999 • 283 citations
Prevention of travellers' diarrhoea by oral B-subunit/whole-cell cholera vaccine
1991 • 278 citations
Mucosal Adjuvanticity and Immunogenicity of LTR72, a Novel Mutant of Escherichia coli Heat-labile Enterotoxin with Partial Knockout of ADP-ribosyltransferase Activity
1998 • 264 citations
Experimental keratoconjunctivitis shigellosa.
1957 • 263 citations
Diarrheal Disease during Operation Desert Shield
1991 • 259 citations
Vaccination against Shigellosis with Attenuated Shigella flexneri 2a Strain SC602
1999 • 228 citations
INCIDENCE AND SEVERITY OF ROTAVIRUS AND ESCHERICHIA COLI DIARRHOEA IN RURAL BANGLADESH Implications for Vaccine Development
1981 • 226 citations
Epidemiologic Patterns of Acute Diarrhea and Endemic Shigella Infections in Children in a Poor Periurban Setting in Santiago, Chile
1991 • 213 citations
Prevalence of Toxin Types and Colonization Factors in Enterotoxigenic Escherichia coli Isolated during a 2-Year Period from Diarrheal Patients in Bangladesh
2000 • 200 citations
Enzyme-linked immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin
1977 • 199 citations
Epidemiologic Studies of Escherichia coli Diarrheal Infections in a Low Socioeconomic Level Peri-Urban Community In Santiago, Chile
1993 • 199 citations
Immunity to Enterotoxigenic Escherichia coli
1979 • 180 citations
Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant
1998 • 172 citations
Prospective study of diarrhoeal disease in a cohort of rural Mexican children: incidence and isolated pathogens during the first two years of life
1988 • 160 citations
Strategy for Cross-Protection amongShigella flexneriSerotypes
1999 • 136 citations
Comparative Susceptibility of Latin American and United States Students to Enteric Pathogens
1976 • 124 citations
Polymyxin B-Induced Release of Low-Molecular-Weight, Heat-Labile Enterotoxin from Escherichia coli
1974 • 123 citations
Optimization of Plasmid Maintenance in the Attenuated Live Vector Vaccine Strain Salmonella typhi CVD 908- htrA
1999 • 121 citations
Enteral immunization and challenge of volunteers given enterotoxigenic E. coli CFA/II encapsulated in biodegradable microspheres
1994 • 117 citations
Differences in serological responses and excretion patterns of volunteers challenged with enterotoxigenic Escherichia coli with and without the colonization factor antigen
1978 • 116 citations
Safety, immunogenicity, and transmissibility in humans of CVD 1203, a live oral Shigella flexneri 2a vaccine candidate attenuated by deletions in aroA and virG
1996 • 113 citations
Role of receptor binding in toxicity, immunogenicity, and adjuvanticity of Escherichia coli heat-labile enterotoxin
1997 • 112 citations
Probing the structure‐activity relationship of Escherichia coli LT‐A by site‐directed mutagenesis
1994 • 110 citations
Evolutionary origin of pathogenic determinants in enterotoxigenic Escherichia coli and Vibrio cholerae O1
1987 • 109 citations
Intestinal Immune Responses to an Inactivated Oral Enterotoxigenic Escherichia coli Vaccine and Associated Immunoglobulin A Responses in Blood
1998 • 105 citations
Engineered deltaguaB-A deltavirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine
1996 • 102 citations
Studies on vaccination against bacillary dysentery. 6. Protection of children by oral immunization with streptomycin-dependent Shigella strains.
1971 • 98 citations
Enterotoxigenic Escherichia coli diarrhoea: acquired immunity and transmission in an endemic area.
1981 • 98 citations
Studies on vaccination against bacillary dysentery. 4. Oral immunization with live monotypic and combined vaccines.
1968 • 94 citations
Safety and immunogenicity of an oral inactivated enterotoxigenic Escherichia coli vaccine
1998 • 93 citations
Shigella flexneri 2a Strain CVD 1207, with Specific Deletions in virG , sen , set , and guaBA , Is Highly Attenuated in Humans
2000 • 91 citations
Oral, Inactivated, Whole Cell EnterotoxigenicEscherichia coliplus Cholera Toxin B Subunit Vaccine: Results of the Initial Evaluation in Children
1999 • 88 citations
Immunization of rabbits with enterotoxigenic E. coli colonization factor antigen (CFA/I) encapsulated in biodegradable microspheres of poly (lactide-co-glycolide)
1993 • 82 citations
Safety and Immunogenicity of an Oral, Killed EnterotoxigenicEscherichia coli‐Cholera Toxin B Subunit Vaccine in Egyptian Adults
1998 • 81 citations
Genetically Detoxified Mutants of Heat-Labile Toxin from Escherichia coli Are Able To Act as Oral Adjuvants
1999 • 78 citations
Improved GM1-enzyme-linked immunosorbent assay for detection of Escherichia coli heat-labile enterotoxin
1983 • 76 citations
Construction and characterization of attenuated delta aroA delta virG Shigella flexneri 2a strain CVD 1203, a prototype live oral vaccine
1994 • 72 citations
Further characterization of delta aroA delta virG Shigella flexneri 2a strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector vaccine for delivering antigens of enterotoxigenic Escherichia coli
1996 • 72 citations
Hemagglutination and Colonization Factors in Enterotoxigenic and Enteropathogenic Escherichia coli that Cause Diarrhea
1980 • 63 citations
Safety and immunogenicity study of the auxotrophic Shigella flexneri 2a vaccine SFL1070 with a deleted aroD gene in adult Swedish volunteers
1995 • 57 citations
Enzyme-linked immunosorbent assay to measure antibodies to purified heat-labile enterotoxins from human and porcine strains of Escherichia coli and to cholera toxin: application in serodiagnosis and seroepidemiology
1985 • 56 citations
Levels of Expression and Immunogenicity of Attenuated Salmonella enterica Serovar Typhimurium Strains Expressing Escherichia coli Mutant Heat-Labile Enterotoxin
1998 • 55 citations
ΔguaBA attenuated Shigella flexneri 2a strain CVD 1204 as a Shigella vaccine and as a live mucosal delivery system for fragment C of tetanus toxin
2000 • 50 citations
Analysis of antigenic determinants in cholera enterotoxin and heat-labile enterotoxins from human and porcine enterotoxigenic Escherichia coli
1983 • 50 citations
Simultaneous expression of CFA/I and CS3 colonization factor antigens of enterotoxigenic Escherichia coli by ΔaroC, ΔaroD Salmonella typhi vaccine strain CVD 908
1995 • 49 citations
In Vivo Expression and Immunoadjuvancy of a Mutant of Heat-Labile Enterotoxin of Escherichia coli in Vaccine and Vector Strains of Vibrio cholerae
1999 • 41 citations
Live oral Shigella vaccine: vaccination schedule and the effect of booster dose.
1974 • 38 citations
Native and Mutant Forms of Cholera Toxin and Heat-Labile Enterotoxin Effectively Enhance Protective Efficacy of Live Attenuated and Heat-KilledShigellaVaccines
1999 • 36 citations
Attenuated Salmonella typhi and Shigella as live oral vaccines and as live vectors.
1997 • 33 citations
Population-based study of the incidence of Shigella diarrhea and causative serotypes in Santiago, Chile
1999 • 32 citations
Purification and analysis of colonization factor antigen I, coli surface antigen 1, and coli surface antigen 3 fimbriae from enterotoxigenic Escherichia coli
1989 • 32 citations
Monoclonal antibodies with an expanded repertoire of specificities and potent neutralizing activity for Escherichia coli heat-labile enterotoxin
1984 • 31 citations
Fimbrial Vaccines
2020 • 8 citations
Novel self-sampling culture method to monitor excretion of live, oral Shigella flexneri 2a vaccine SC602 during a community-based phase 1 trial
1999 • 6 citations