Safety, immunogenicity, and transmissibility in humans of CVD 1203, a live oral Shigella flexneri 2a vaccine candidate attenuated by deletions in aroA and virG

Biometry: The Principles and Practice of Statistics in Biological Research

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A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

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Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin.

1989 • 724 citations

The principles and practice of statistics in biological research

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Tumor necrosis factor-α

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1990 • 233 citations

Serum immune response to Shigella protein antigens in rhesus monkeys and humans infected with Shigella spp

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Identification and cloning of a novel plasmid-encoded enterotoxin of enteroinvasive Escherichia coli and Shigella strains

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The Response of Man to Virulent Shigella flexneri 2a

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Prevention of Shigellosis by a Salmonella typhi-Shigella sonnei Bivalent Vaccine

1987 • 175 citations

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1995 • 174 citations

Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosis

1991 • 158 citations

Shigella enterotoxin 1: an enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitro.

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New perspectives in vaccine development: mucosal immunity to infections.

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Studies in volunteers to evaluate candidate Shigella vaccines: further experience with a bivalent Salmonella typhi-Shigella sonnei vaccine and protection conferred by previous Shigella sonnei disease

1990 • 145 citations

Cytokines in stools of children with inflammatory bowel disease or infective diarrhoea.

1993 • 127 citations

Cytokine Secretion in Acute Shigellosis Is Correlated to Disease Activity and Directed More to Stool than to Plasma

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Evaluation in humans of attenuated Vibrio cholerae El Tor Ogawa strain Texas Star-SR as a live oral vaccine

1984 • 112 citations

A modified Shigella volunteer challenge model in which the inoculum is administered with bicarbonate buffer: clinical experience and implications for Shigella infectivity

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Auxotrophic Salmonella typhi as live vaccine

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Evaluation in volunteers of a candidate live oral attenuated Salmonella typhi vector vaccine.

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Evaluation of the safety, immunogenicity, and efficacy in healthy adults of four doses of live oral hybrid Escherichia coli-Shigella flexneri 2a vaccine strain EcSf2a-2

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Safety, immunogenicity, and efficacy in monkeys and humans of invasive Escherichia coli K-12 hybrid vaccine candidates expressing Shigella flexneri 2a somatic antigen

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Changing Pattern of Resistant Shiga Bacillus (Shigella dysenteriae Type 1) and Shigella flexneri in Bangladesh

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Specific immunoglobulin A-secreting cells in peripheral blood of humans following oral immunization with a bivalent Salmonella typhi-Shigella sonnei vaccine or infection by pathogenic S. sonnei

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Concentrations of interleukin 6 and tumour necrosis factor in serum and stools of children with Shigella dysenteriae 1 infection.

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Further characterization of delta aroA delta virG Shigella flexneri 2a strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector vaccine for delivering antigens of enterotoxigenic Escherichia coli

1996 • 72 citations

Construction and characterization of attenuated delta aroA delta virG Shigella flexneri 2a strain CVD 1203, a prototype live oral vaccine

1994 • 72 citations

Systemic and mucosal immune responses to rhesus rotavirus vaccine MMU 18006

1988 • 66 citations

Antimicrobial-Resistant Epidemic Shigella Dysenteriae Type 1 in Zambia: Modes of Transmission

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Safety and immunogenicity study of the auxotrophic Shigella flexneri 2a vaccine SFL1070 with a deleted aroD gene in adult Swedish volunteers

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Studies with a New Generation of Oral Attenuated Shigella Vaccine: Escherichia coli Bearing Surface Antigens of Shigella flexneri

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Construction of an auxotrophic Shigella flexneri strain for use as a live vaccine

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Vaccine strain Sh. flexneri T32-Istrati. Studies in animals and in volunteers. Antidysentery immunoprophylaxis and immunotherapy by live vaccine Vadizen (Sh. flexneri T32-Istrati).

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SHIGELLOSIS IN CUSTODIAL INSTITUTIONS1

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Cytokines in the stools of children with complicated shigellosis

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