Cholesterol, a Cell Size-dependent Signal That Regulates Glucose Metabolism and Gene Expression in Adipocytes

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

1993 • 7,219 citations

Lipid rafts and signal transduction

2000 • 6,079 citations

Metabolism of Isolated Fat Cells

1964 • 4,431 citations

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

Obesity and insulin resistance

2000 • 3,076 citations

Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?

2000 • 1,753 citations

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1983 • 1,639 citations

Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid¹

1998 • 1,562 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

2001 • 1,202 citations

Sterol-dependent Transactivation of theABC1 Promoter by the Liver X Receptor/Retinoid X Receptor

2000 • 962 citations

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

1998 • 768 citations

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance

2000 • 733 citations

Obesity in the new millennium

2000 • 707 citations

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

1998 • 686 citations

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean

2000 • 615 citations

ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose

1999 • 540 citations

Cell cholesterol efflux: integration of old and new observations provides new insights

1999 • 502 citations

Physiology and Pathophysiology of the Adipose Tissue Renin-Angiotensin System

2000 • 467 citations

Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation.

1994 • 425 citations

Localization of the insulin receptor in caveolae of adipocyte plasma membrane

1999 • 364 citations

The LXRs: a new class of oxysterol receptors

1998 • 358 citations

Cholesterol Depletion Disrupts Caveolae and Insulin Receptor Signaling for Metabolic Control via Insulin Receptor Substrate-1, but Not for Mitogen-activated Protein Kinase Control

2001 • 339 citations

Sterol Regulation of Fatty Acid Synthase Promoter

1995 • 323 citations

Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver.

1995 • 305 citations

Caveolin Is an Activator of Insulin Receptor Signaling

1998 • 297 citations

Tissue-specific nutritional regulation of angiotensinogen in adipose tissue.

1992 • 243 citations

Adipose tissue and cholesterol metabolism.

1984 • 205 citations

Caveolin-1 Interacts with the Insulin Receptor and Can Differentially Modulate Insulin Signaling in Transfected Cos-7 Cells and Rat Adipose Cells

1999 • 188 citations

Increased Adipose Angiotensinogen Gene Expression in Human Obesity

2000 • 170 citations

Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes

1997 • 141 citations

Obesity-related Overexpression of Fatty-acid Synthase Gene in Adipose Tissue Involves Sterol Regulatory Element-binding Protein Transcription Factors

1998 • 132 citations

Human adipocyte cholesterol. Concentration, localization, synthesis, and turnover.

1975 • 123 citations

Sterol Regulatory Element-Binding Protein-1a Binds to cis Elements in the Promoter of the Rat High Density Lipoprotein Receptor SR-BI Gene1

1999 • 113 citations

Regulation of cholesterol synthesis and storage in fat cells

1975 • 106 citations

Human Uncoupling Proteins and Obesity

1999 • 92 citations

Mechanisms of Decreased Insulin Responsiveness of Large Adipocytes

1977 • 90 citations

Genetic regulation of fatty acid synthetase expression in adipose tissue: overtranscription of the gene in genetically obese rats.

1992 • 63 citations

Differential regulation of adipose tissue glucose transporters in genetic obesity (fatty rat). Selective increase in the adipose cell/muscle glucose transporter (GLUT 4) expression.

1991 • 58 citations

Increased insulin sensitivity and responsiveness of glucose metabolism in adipocytes from female versus male rats.

1985 • 40 citations

Plasma Membrane Lipid Order and Composition during Adipocyte Differentiation of 3T3F442A Cells

1989 • 38 citations

Decreased Activation Rate of Insulin-Stimulated Glucose Transport in Adipocytes From Obese Subjects

1989 • 33 citations

Alteration in membrane lipid order and composition in metabolically hyperactive fatty rat adipocytes

1994 • 33 citations