ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

1969 • 4,428 citations

The SREBP Pathway: Regulation of Cholesterol Metabolism by Proteolysis of a Membrane-Bound Transcription Factor

1997 • 3,702 citations

An established preadipose cell line and its differentiation in culture II. Factors affecting the adipose conversion

1975 • 1,358 citations

ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism.

1996 • 1,004 citations

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

1994 • 994 citations

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

1993 • 906 citations

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

1997 • 816 citations

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

1998 • 768 citations

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells.

1997 • 744 citations

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

1998 • 686 citations

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

1998 • 658 citations

The adenovirus major late transcription factor USF is a member of the helix-loop-helix group of regulatory proteins and binds to DNA as a dimer.

1990 • 584 citations

ADD1: a Novel Helix-Loop-Helix Transcription Factor Associated with Adipocyte Determination and Differentiation

1993 • 575 citations

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

1997 • 438 citations

Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.

1984 • 436 citations

ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation.

1993 • 351 citations

MECHANISMS BY WHICH CARBOHYDRATES REGULATE EXPRESSION OF GENES FOR GLYCOLYTIC AND LIPOGENIC ENZYMES

1997 • 350 citations

Dual DNA Binding Specificity of ADD1/SREBP1 Controlled by a Single Amino Acid in the Basic Helix-Loop-Helix Domain

1995 • 326 citations

Independent regulation of sterol regulatory element-binding proteins 1 and 2 in hamster liver.

1995 • 305 citations

REGULATION OF THE EXPRESSION OF LIPOGENIC ENZYME GENES BY CARBOHYDRATE

1997 • 294 citations

AMP-activated Protein Kinase Inhibits the Glucose-activated Expression of Fatty Acid Synthase Gene in Rat Hepatocytes

1998 • 257 citations

Glucose stimulation of lipogenic enzyme gene expression in cultured white adipose tissue. A role for glucose 6-phosphate.

1992 • 184 citations

Identification of an insulin response element in the fatty acid synthase promoter.

1994 • 155 citations

Upstream Stimulatory Factor Proteins Are Major Components of the Glucose Response Complex of the L-type Pyruvate Kinase Gene Promoter

1995 • 109 citations

Rapid synergistic interaction between thyroid hormone and carbohydrate on mRNAS14 induction.

1986 • 103 citations

Carbohydrate Regulation of Hepatic Gene Expression

1997 • 93 citations

Respective roles of glucose, fructose, and insulin in the regulation of the liver-specific pyruvate kinase gene promoter.

1994 • 92 citations

Induction of Fatty‐Acid‐Synthase Gene Expression by Glucose in Primary Culture of Rat Hepatocytes

1995 • 92 citations

Induction of fatty acid synthase and S14 gene expression by glucose, xylitol and dihydroxyacetone in cultured rat hepatocytes is closely correlated with glucose 6-phosphate concentrations

1997 • 86 citations

Glucose‐dependent regulation of the <scp>l</scp> ‐pyruvate kinase gene in a hepatoma cell line is independent of insulin and cyclic AMP

1994 • 70 citations

A Double Recombinant Adenovirus Expressing the Costimulatory Molecule B7-1 (Murine) and Human IL-2 Induces Complete Tumor Regression in a Murine Breast Adenocarcinoma Model

1998 • 67 citations

Lipogenic enzyme activities and mRNA in rat adipose tissue at weaning

1990 • 47 citations

Vasomotor Dysfunction Early after Exposure of Normal Rabbit Arteries to an Adenoviral Vector

1997 • 38 citations

Gene expression of lipid storage-related enzymes in adipose tissue of the genetically obese Zucker rat. Co-ordinated increase in transcriptional activity and potentiation by hyperinsulinaemia

1992 • 30 citations

Lack of evidence of phenotypic complementation of E1A/E1B-deleted adenovirus type 5 upon superinfection by wild-type virus in the cotton rat

1995 • 20 citations