Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytes

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Identification and expression cloning of a leptin receptor, OB-R

1995 • 3,498 citations

Abnormal splicing of the leptin receptor in diabetic mice

1996 • 2,361 citations

TRANSCRIPTIONAL REGULATION OF GENE EXPRESSION DURING ADIPOCYTE DIFFERENTIATION

1995 • 1,033 citations

Endotoxin and cytokines induce expression of leptin, the ob gene product, in hamsters.

1996 • 864 citations

Defective STAT signaling by the leptin receptor in diabetic mice.

1996 • 803 citations

Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.

1980 • 593 citations

Regulated expression of the obese gene product (leptin) in white adipose tissue and 3T3-L1 adipocytes.

1995 • 522 citations

Regulation of Expression of ob mRNA and Protein by Glucocorticoids and cAMP

1996 • 497 citations

Induction of ob Gene Expression by Corticosteroids Is Accompanied by Body Weight Loss and Reduced Food Intake

1995 • 485 citations

Activation of β3 Adrenergic Receptors Suppresses Leptin Expression and Mediates a Leptin-Independent Inhibition of Food Intake in Mice

1996 • 315 citations

Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line

1979 • 282 citations

Regulation of ob gene mRNA levels in cultured adipocytes

1996 • 268 citations

Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats.

1995 • 213 citations

Dexamethasone Regulates Obese Expression in Isolated Rat Adipocytes

1995 • 200 citations

Transcriptional activation of the mouse obese (ob) gene by CCAAT/enhancer binding protein alpha.

1996 • 186 citations

The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.

1996 • 160 citations

The Mouse obese Gene

1995 • 153 citations

Glucocorticoids reciprocally regulate expression of the CCAAT/enhancer-binding protein alpha and delta genes in 3T3-L1 adipocytes and white adipose tissue.

1994 • 129 citations

Tackling a weighty problem

1992 • 123 citations

Differential Expression of ob mRNA in Rat Adipose Tissues in Response to Insulin

1996 • 79 citations

Identification of the promoter of the mouse obese gene.

1996 • 66 citations

Expression of the phosphoenolpyruvate carboxykinase gene in 3T3-F442A adipose cells: opposite effects of dexamethasone and isoprenaline on transcription

1995 • 42 citations

Hepatoma cell-specific expression of a retrovirally transferred gene is achieved by α-fetoprotein but not insulinlike growth factor II regulatory sequences

1995 • 25 citations